4W8I
 
 | | Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase | | Descriptor: | Probable sphingosine-1-phosphate lyase | | Authors: | Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-08-24 | | Release date: | 2014-11-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3D3R
 | | Crystal structure of the hydrogenase assembly chaperone HypC/HupF family protein from Shewanella oneidensis MR-1 | | Descriptor: | Hydrogenase assembly chaperone hypC/hupF | | Authors: | Kim, Y, Skarina, T, Onopriyenko, O, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-05-12 | | Release date: | 2008-05-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structure of the Hydrogenase Assembly Chaperone HypC/HupF Family Protein from Shewanella oneidensis MR-1.
To be Published
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1ML8
 | | structural genomics | | Descriptor: | hypothetical protein (crp region) | | Authors: | Korolev, S, Skarina, T, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2002-08-30 | | Release date: | 2003-04-22 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural genomics
To be Published
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3MGA
 | | 2.4 Angstrom Crystal Structure of Ferric Enterobactin Esterase (fes) from Salmonella typhimurium | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Enterochelin esterase, ... | | Authors: | Minasov, G, Wawrzak, Z, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2010-04-05 | | Release date: | 2010-04-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | 2.4 Angstrom Crystal Structure of Ferric Enterobactin Esterase (fes) from Salmonella typhimurium.
TO BE PUBLISHED
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2R8T
 | | Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate | | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class II glpX, UNKNOWN ATOM OR ION | | Authors: | Lunin, V.V, Skarina, T, Brown, G, Yakunin, A, Edwards, A.M, Savchenko, A. | | Deposit date: | 2007-09-11 | | Release date: | 2008-08-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the fructose 1,6-bisphosphatase GlpX
from E.coli in the complex with fructose 1,6-bisphosphate
To be Published
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2RAE
 | | Crystal structure of a TetR/AcrR family transcriptional regulator from Rhodococcus sp. RHA1 | | Descriptor: | Transcriptional regulator, AcrR family protein | | Authors: | Zhang, R, Skarina, T, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-09-14 | | Release date: | 2007-09-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The crystal structure of a TetR/AcrR family transcriptional regulator from Rhodococcus sp. RHA1
To be Published
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8CRV
 | | Crystal Structure of the Carbamate Kinase from Pseudomonas aeruginosa | | Descriptor: | 1,2-ETHANEDIOL, Carbamate kinase, FORMIC ACID, ... | | Authors: | Kim, Y, Skarina, T, Mesa, N, Stogios, P, Savchenko, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2022-05-11 | | Release date: | 2022-08-10 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the Carbamate Kinase from Pseudomonas aeruginosa
To Be Published
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2FXA
 | | Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis. | | Descriptor: | 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, PENTAETHYLENE GLYCOL, ... | | Authors: | Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-02-03 | | Release date: | 2006-03-14 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis.
TO BE PUBLISHED
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2G8Y
 | | The structure of a putative malate/lactate dehydrogenase from E. coli. | | Descriptor: | 1,2-ETHANEDIOL, Malate/L-lactate dehydrogenases, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-03-03 | | Release date: | 2006-04-25 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The structure of a putative malate/lactate dehydrogenase from E. coli.
To be Published
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2GFQ
 | | Structure of Protein of Unknown Function PH0006 from Pyrococcus horikoshii | | Descriptor: | MAGNESIUM ION, SULFATE ION, UPF0204 protein PH0006 | | Authors: | Cuff, M.E, Skarina, T, Gorodichtchenskaia, E, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-03-22 | | Release date: | 2006-04-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure of hypothetical protein ph0006 from Pyrococcus horikoshii
To be Published
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8SDC
 | | Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme | | Descriptor: | Alpha/beta hydrolase fold protein, CHLORIDE ION | | Authors: | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | | Deposit date: | 2023-04-06 | | Release date: | 2023-09-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases.
Febs J., 290, 2023
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8SDD
 | | Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate | | Descriptor: | Alpha/beta hydrolase fold protein | | Authors: | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | | Deposit date: | 2023-04-06 | | Release date: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases.
Febs J., 290, 2023
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2GEN
 | | Structural Genomics, the crystal structure of a probable transcriptional regulator from Pseudomonas aeruginosa PAO1 | | Descriptor: | probable transcriptional regulator | | Authors: | Tan, K, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-03-20 | | Release date: | 2006-04-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The crystal structure of a probable transcriptional regulator from Pseudomonas aeruginosa PAO1
To be Published
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2G84
 | | Cytidine and deoxycytidylate deaminase zinc-binding region from Nitrosomonas europaea. | | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Cytidine and deoxycytidylate deaminase zinc-binding region, ... | | Authors: | Osipiuk, J, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-03-01 | | Release date: | 2006-04-04 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | X-ray crystal structure of Cytidine and deoxycytidylate deaminase zinc-binding region from Nitrosomonas europaea.
To be Published
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2G7L
 | | Crystal structure of putative transcription regulator SCO7704 from Streptomyces coelicor | | Descriptor: | TetR-family transcriptional regulator | | Authors: | Ezersky, A, Lunin, V.V, Skarina, T, Wierzbicka, M, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-02-28 | | Release date: | 2006-03-14 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of putative transcription regulator SCO7704 from Streptomyces coelicor
To be Published
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2G7U
 | | 2.3 A structure of putative catechol degradative operon regulator from Rhodococcus sp. RHA1 | | Descriptor: | transcriptional regulator | | Authors: | Zheng, H, Skarina, T, Chruszcz, M, Cymborowski, M, Grabowski, M, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-03-01 | | Release date: | 2006-04-04 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | 2.3 A structure of putative catechol degradative operon regulator from
Rhodococcus sp. RHA1
To be Published
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6U83
 | | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-ALANINE, Outer membrane associated protein, ... | | Authors: | Michalska, K, Skarina, T, Stogios, P.J, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-09-04 | | Release date: | 2019-09-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.3566 Å) | | Cite: | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4
To Be Published
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4IC1
 | | Crystal structure of SSO0001 | | Descriptor: | IRON/SULFUR CLUSTER, MANGANESE (II) ION, Uncharacterized protein | | Authors: | Nocek, B, Skarina, T, Lemak, S, Beloglazova, N, Flick, R, Brown, G, Savchenko, A, Joachimiak, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2012-12-09 | | Release date: | 2013-01-16 | | Last modified: | 2014-07-02 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Toroidal structure and DNA cleavage by the CRISPR-associated [4Fe-4S] cluster containing Cas4 nuclease SSO0001 from Sulfolobus solfataricus.
J.Am.Chem.Soc., 135, 2013
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4XI1
 | | Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase LubX, GLYCEROL, ... | | Authors: | Stogios, P.J, Quaile, T, Skarina, T, Cuff, M, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2015-01-06 | | Release date: | 2015-01-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.983 Å) | | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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4WZ2
 | | Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, Ile175Met mutant | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase LubX, HEXANE-1,6-DIOL | | Authors: | Stogios, P.J, Qualie, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-11-18 | | Release date: | 2015-01-28 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (3.408 Å) | | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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4WZ3
 | | Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2 | | Descriptor: | E3 ubiquitin-protein ligase LubX, Ubiquitin-conjugating enzyme E2 D2 | | Authors: | Stogios, P.J, Quaile, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-11-18 | | Release date: | 2015-01-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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4WZ0
 | | Crystal structure of U-box 1 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris | | Descriptor: | E3 ubiquitin-protein ligase LubX | | Authors: | Stogios, P.J, Quaile, A.T, Skarina, T, Stein, A, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-11-18 | | Release date: | 2015-01-14 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (1.954 Å) | | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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5VYV
 | | Crystal structure of a protein of unknown function YceH/ECK1052 involved in membrane biogenesis from Escherichia coli | | Descriptor: | DI(HYDROXYETHYL)ETHER, UPF0502 protein YceH | | Authors: | Stogios, P.J, Skarina, T, McChesney, C, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-05-26 | | Release date: | 2017-06-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Crystal structure of a protein of unknown function YceH/ECK1052 involved in membrane biogenesis from Escherichia coli
To Be Published
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4R5Q
 | | Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster | | Descriptor: | CRISPR-associated exonuclease, Cas4 family, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Nocek, B, Skarina, T, Lemak, S, Brown, G, Savchenko, A, Joachimiak, A, Yakunin, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-08-21 | | Release date: | 2014-09-17 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster
To be Published
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4RO3
 | | 1.8 Angstrom Crystal Structure of the N-terminal Domain of Protein with Unknown Function from Vibrio cholerae. | | Descriptor: | Hypothetical Protein, SULFATE ION | | Authors: | Minasov, G, Wawrzak, Z, Stogios, P.J, Skarina, T, Seed, K.D, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2014-10-27 | | Release date: | 2014-12-03 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | 1.8 Angstrom Crystal Structure of the N-terminal Domain of Protein with Unknown Function from Vibrio cholerae.
To be Published
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