5L3S
 
 | | Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY | | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2016-05-24 | | Release date: | 2016-06-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
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5LNV
 | | Crystal structure of Arabidopsis thaliana Pdx1-I320 complex from multiple crystals | | Descriptor: | (4~{S})-4-azanyl-5-oxidanyl-pent-1-en-3-one, PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... | | Authors: | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | | Deposit date: | 2016-08-06 | | Release date: | 2017-01-18 | | Last modified: | 2018-09-19 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.
Nat. Chem. Biol., 13, 2017
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5LNT
 | | Crystal structure of Arabidopsis thaliana Pdx1K166R-preI320 complex | | Descriptor: | PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.1, [(~{E},4~{S})-4-azanyl-3-oxidanylidene-pent-1-enyl] dihydrogen phosphate | | Authors: | Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. | | Deposit date: | 2016-08-06 | | Release date: | 2017-01-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.
Nat. Chem. Biol., 13, 2017
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5NZU
 | | The structure of the COPI coat linkage II | | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2017-05-15 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (15 Å) | | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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5NZS
 | | The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor | | Descriptor: | ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ... | | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2017-05-15 | | Release date: | 2017-06-28 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (10.1 Å) | | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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5NZR
 | | The structure of the COPI coat leaf | | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2017-05-15 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (9.2 Å) | | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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5NZV
 | | The structure of the COPI coat linkage IV | | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2017-05-15 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (17.299999 Å) | | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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5NZT
 | | The structure of the COPI coat linkage I | | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | | Deposit date: | 2017-05-15 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (17 Å) | | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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5MU7
 | | Crystal Structure of the beta/delta-COPI Core Complex | | Descriptor: | Coatomer subunit beta, Coatomer subunit delta-like protein | | Authors: | Kopp, J, Aderhold, P, Wieland, F, Sinning, I. | | Deposit date: | 2017-01-12 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
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6QTB
 | | Crystal structure of Rea1-MIDAS/Ytm1-UBL complex from Chaetomium thermophilum | | Descriptor: | GLYCEROL, MAGNESIUM ION, Midasin,Midasin, ... | | Authors: | Ahmed, Y.L, Thoms, M, Hurt, E, Sinning, I. | | Deposit date: | 2019-02-22 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin-ligand-type complexes.
Nat Commun, 10, 2019
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6RYI
 | | WUS-HD bound to G-Box DNA | | Descriptor: | DNA (5'-D(P*CP*CP*CP*AP*TP*CP*AP*CP*GP*TP*GP*AP*CP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*TP*CP*AP*CP*GP*TP*GP*AP*TP*GP*GP*G)-3'), Protein WUSCHEL | | Authors: | Sloan, J.J, Wild, K, Sinning, I. | | Deposit date: | 2019-06-10 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.691 Å) | | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
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6RY3
 | | Structure of the WUS homeodomain | | Descriptor: | ACETYL GROUP, Protein WUSCHEL, SULFATE ION | | Authors: | Sloan, J.J, Wild, K, Sinning, I. | | Deposit date: | 2019-06-10 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.374 Å) | | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
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6SO5
 | | Homo sapiens WRB/CAML heterotetramer in complex with a TRC40 dimer | | Descriptor: | ATPase ASNA1, Calcium signal-modulating cyclophilin ligand, Tail-anchored protein insertion receptor WRB, ... | | Authors: | McDowell, M.A, Heimes, M, Wild, K, Flemming, D, Sinning, I. | | Deposit date: | 2019-08-29 | | Release date: | 2020-09-09 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex.
Mol.Cell, 80, 2020
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6SR6
 | | Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | | Authors: | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | | Deposit date: | 2019-09-05 | | Release date: | 2020-03-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Nat Commun, 11, 2020
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6SXO
 | | Cryo-EM structure of the human Ebp1-ribosome complex | | Descriptor: | 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ... | | Authors: | Wild, K, Aleksic, M, Pfeffer, M, Sinning, I. | | Deposit date: | 2019-09-26 | | Release date: | 2020-02-19 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.
Nat Commun, 11, 2020
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6QT8
 | | Crystal structure of Rea1-MIDAS domain from Chaetomium thermophilum | | Descriptor: | GLYCEROL, IODIDE ION, Midasin, ... | | Authors: | Ahmed, Y.L, Thoms, M, Hurt, E, Sinning, I. | | Deposit date: | 2019-02-22 | | Release date: | 2019-08-07 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin-ligand-type complexes.
Nat Commun, 10, 2019
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6RYD
 | | WUS-HD bound to TGAA DNA | | Descriptor: | DNA (5'-D(*AP*GP*TP*GP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*CP*AP*CP*T)-3'), MAGNESIUM ION, ... | | Authors: | Sloan, J.J, Wild, K, Sinning, I. | | Deposit date: | 2019-06-10 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.575 Å) | | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
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6RYL
 | | WUS-HD bound to TAAT DNA | | Descriptor: | DNA (5'-D(P*CP*AP*CP*AP*AP*CP*CP*CP*AP*TP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*TP*AP*AP*TP*GP*GP*GP*TP*TP*GP*TP*G)-3'), Protein WUSCHEL | | Authors: | Sloan, J.J, Wild, K, Sinning, I. | | Deposit date: | 2019-06-10 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Nat Commun, 11, 2020
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5MB9
 | | Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Gumiero, A, Weyer, F.A, Valentin Gese, G, Lapouge, K, Sinning, I. | | Deposit date: | 2016-11-07 | | Release date: | 2016-12-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.
Nat. Struct. Mol. Biol., 24, 2017
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5M73
 | | Structure of the human SRP S domain with SRP72 RNA-binding domain | | Descriptor: | GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... | | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | | Deposit date: | 2016-10-26 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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5NIY
 | | Signal recognition particle-docking protein FtsY | | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY | | Authors: | Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I. | | Deposit date: | 2017-03-27 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane.
Structure, 26, 2018
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5NNR
 | | Structure of Naa15/Naa10 bound to HypK-THB | | Descriptor: | HypK, N-terminal acetyltransferase-like protein, Naa10 | | Authors: | Weyer, F.A, Gumiero, A, Kopp, J, Sinning, I. | | Deposit date: | 2017-04-10 | | Release date: | 2017-06-14 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of HypK regulating N-terminal acetylation by the NatA complex.
Nat Commun, 8, 2017
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5NNP
 | | Structure of Naa15/Naa10 bound to HypK-THB | | Descriptor: | CARBOXYMETHYL COENZYME *A, GLYCEROL, N-terminal acetyltransferase-like protein, ... | | Authors: | Weyer, F.A, Gumiero, A, Kopp, J, Sinning, I. | | Deposit date: | 2017-04-10 | | Release date: | 2017-06-14 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Structural basis of HypK regulating N-terminal acetylation by the NatA complex.
Nat Commun, 8, 2017
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5NQH
 | | Structure of the human Fe65-PTB2 homodimer | | Descriptor: | Amyloid beta A4 precursor protein-binding family B member 1, GLYCEROL, SULFATE ION | | Authors: | Feilen, L.P, Haubrich, K, Sinning, I, Konietzko, U, Kins, S, Simon, B, Wild, K. | | Deposit date: | 2017-04-20 | | Release date: | 2017-05-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction.
Front Mol Neurosci, 10, 2017
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5N1A
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