6SO5

Homo sapiens WRB/CAML heterotetramer in complex with a TRC40 dimer

Summary for 6SO5

• Entry DOI: 10.2210/pdb6so5/pdb
• Related: 6SO6
• EMDB information: 10266 10267
• Descriptor: ATPase ASNA1, Tail-anchored protein insertion receptor WRB, Calcium signal-modulating cyclophilin ligand, ... (4 entities in total)
• Functional Keywords: er, insertase, complex, tail-anchor, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 150560.23

Authors

McDowell, M.A.,Heimes, M.,Wild, K.,Flemming, D.,Sinning, I. (deposition date: 2019-08-29, release date: 2020-09-09, Last modification date: 2021-02-17)

• Primary citation: McDowell, M.A.,Heimes, M.,Fiorentino, F.,Mehmood, S.,Farkas, A.,Coy-Vergara, J.,Wu, D.,Bolla, J.R.,Schmid, V.,Heinze, R.,Wild, K.,Flemming, D.,Pfeffer, S.,Schwappach, B.,Robinson, C.V.,Sinning, I.; Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex.; Mol.Cell, 80:72-, 2020; PubMed: 32910895; DOI: 10.1016/j.molcel.2020.08.012

Experimental method

ELECTRON MICROSCOPY (4.2 Å)