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PDB: 7 件
6GWQ
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BU of 6gwq by Molmil
Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42)
分子名称: Plasminogen Activator Inhibitor-1, VHH-2g-42
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2018-06-25
公開日2020-01-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
7AQL
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BU of 7aql by Molmil
Crystal Structure of an Anti-Plasminogen Activator Inhibitor-1 (PAI-1) scFv antibody fragment (scFv-33H1F7)
分子名称: SULFATE ION, scFv-33H1F7
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2020-10-22
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of an Anti-Plasminogen Activator Inhibitor-1 (PAI-1) scFv antibody fragment (scFv-33H1F7)
To Be Published
6ZRV
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BU of 6zrv by Molmil
Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with an Inhibitory Nanobody (VHH-s-a93, Nb93)
分子名称: Plasminogen activator inhibitor 1, VHH-s-a93 (Nb93)
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2020-07-15
公開日2020-08-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity.
Int J Mol Sci, 21, 2020
6GWP
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BU of 6gwp by Molmil
Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64)
分子名称: Plasminogen Activator Inhibitor-1, VHH-2g-42, VHH-2w-64
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2018-06-25
公開日2020-01-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
6GWN
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BU of 6gwn by Molmil
Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64)
分子名称: Plasminogen activator inhibitor 1, VHH-2g-42, VHH-2w-64
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2018-06-25
公開日2020-01-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
7AQF
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BU of 7aqf by Molmil
Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab)
分子名称: 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1
著者Sillen, M, Strelkov, S.V, Declerck, P.J.
登録日2020-10-21
公開日2021-02-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484.
Int J Mol Sci, 22, 2021
7AQG
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BU of 7aqg by Molmil
Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F)
分子名称: 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1, VHH-2g-42 (Nb42), ...
著者Sillen, M, Strelkov, S.V, Declerck, P.J.
登録日2020-10-21
公開日2021-02-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484.
Int J Mol Sci, 22, 2021

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件を2024-05-15に公開中

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