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PDB: 16 件

2OM2
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Crystal Structure Of Human G[alpha]i1 Bound To The Goloco Motif Of Rgs14
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Siderovski, D.P, Kimple, R.J.
登録日2007-01-20
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-based Protocol for Identifying Mutations that Enhance Protein-Protein Binding Affinities.
J.Mol.Biol., 371, 2007
4MIT
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BU of 4mit by Molmil
Crystal structure of E. histolytica RacC bound to the EhPAK4 PBD
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho family GTPase, ...
著者Bosch, D.E, Siderovski, D.P.
登録日2013-09-02
公開日2014-09-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Entamoeba histolytica RacC Selectively Engages p21-Activated Kinase Effectors.
Biochemistry, 54, 2015
4DVG
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Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Diaphanous protein, MAGNESIUM ION, ...
著者Bosch, D.E, Siderovski, D.P.
登録日2012-02-23
公開日2012-11-14
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin.
Biochemistry, 51, 2012
1Y3A
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Structure of G-Alpha-I1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Johnston, C.A, Willard, F.S, Jezyk, M.R, Fredericks, Z, Bodor, E.T, Jones, M.B, Blaesius, R, Harden, T.K, Sondek, J, Watts, V.J, Ramer, J.K, Siderovski, D.P.
登録日2004-11-24
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of G-Alpha-I1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange
Structure, 7, 2005
2G83
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Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Johnston, C.A, Ramer, J.K, Blaesius, R, Kuhlman, B, Arshavsky, V.Y, Siderovski, D.P.
登録日2006-03-01
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Minimal Determinants for Binding Activated Galpha from the Structure of a Galpha(i1)-Peptide Dimer.
Biochemistry, 45, 2006
2PBI
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BU of 2pbi by Molmil
The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure
分子名称: GLYCEROL, Guanine nucleotide-binding protein subunit beta 5, Regulator of G-protein signaling 9
著者Cheever, M.L, Snyder, J.T, Gershburg, S, Siderovski, D.P, Harden, T.K, Sondek, J.
登録日2007-03-28
公開日2008-01-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the multifunctional Gbeta5-RGS9 complex.
Nat.Struct.Mol.Biol., 15, 2008
4FID
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Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1
分子名称: G protein alpha subunit, GUANOSINE-5'-DIPHOSPHATE
著者Bosch, D.E, Kimple, A.J, Muller, R.E, Gigure, P.M, Willard, F.S, Machius, M, Temple, B.R, Siderovski, D.P.
登録日2012-06-08
公開日2012-11-28
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica.
Plos Pathog., 8, 2012
4GPR
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BU of 4gpr by Molmil
Crystal structure of EhUbc5, a ubiquitin conjugating enzyme from Entamoeba histolytica
分子名称: COBALT (II) ION, Ubiquitin-conjugating enzyme family protein
著者Bosch, D.E, Siderovski, D.P.
登録日2012-08-21
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica.
J.Biol.Chem., 288, 2013
4GU2
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Crystal structure of ubiquitin from Entamoeba histolytica to 1.35 Angstrom
分子名称: Ubiquitin
著者Bosch, D.E, Siderovski, D.P.
登録日2012-08-29
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica.
J.Biol.Chem., 288, 2013
4GOU
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Crystal structure of an RGS-RhoGEF from Entamoeba histolytica
分子名称: EhRGS-RhoGEF
著者Bosch, D.E, Kimple, A.J, Muller, R.E, Willard, F.S, Machius, M, Siderovski, D.P.
登録日2012-08-20
公開日2013-01-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis.
Structure, 21, 2013
4GSW
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Crystal structure of ubiquitin from Entamoeba histolytica to 2.15 Angstrom
分子名称: SULFATE ION, Ubiquitin
著者Bosch, D.E, Siderovski, D.P.
登録日2012-08-28
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica.
J.Biol.Chem., 288, 2013
1IHJ
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BU of 1ihj by Molmil
Crystal Structure of the N-terminal PDZ domain of InaD in complex with a NorpA C-terminal peptide
分子名称: InaD, phospholipase C
著者Kimple, M.E, Siderovski, D.P, Sondek, J.
登録日2001-04-19
公開日2001-08-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA.
EMBO J., 20, 2001
1KJY
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BU of 1kjy by Molmil
Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14
分子名称: CESIUM ION, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT, ...
著者Kimple, R.J, Kimple, M.E, Betts, L, Sondek, J, Siderovski, D.P.
登録日2001-12-05
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.
Nature, 416, 2002
1KZ7
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BU of 1kz7 by Molmil
Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42
分子名称: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
著者Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
登録日2002-02-06
公開日2002-03-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1LB1
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BU of 1lb1 by Molmil
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
分子名称: Guanine nucleotide exchange factor DBS, Transforming protein RhoA
著者Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J.
登録日2002-04-01
公開日2002-05-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
1KZG
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BU of 1kzg by Molmil
DbsCdc42(Y889F)
分子名称: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
著者Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
登録日2002-02-06
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002

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