2OM2

Crystal Structure Of Human G[alpha]i1 Bound To The Goloco Motif Of Rgs14

Summary for 2OM2

Related1KJY
DescriptorGuanine nucleotide-binding protein G(i), alpha-1 subunit, Regulator of G-protein signalling 14 GoLoco motif peptide, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsarginine finger, rgs14 goloco, signaling protein
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (By similarity) P63096
Total number of polymer chains4
Total molecular weight83440.95
Authors
Siderovski, D.P.,Kimple, R.J. (deposition date: 2007-01-20, release date: 2007-07-10, Last modification date: 2011-07-13)
Primary citation
Sammond, D.W.,Eletr, Z.M.,Purbeck, C.,Kimple, R.J.,Siderovski, D.P.,Kuhlman, B.
Structure-based Protocol for Identifying Mutations that Enhance Protein-Protein Binding Affinities.
J.Mol.Biol., 371:1392-1404, 2007
PubMed: 17603074 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2007.05.096
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258110.7%2.1%7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution