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2OM2

Crystal Structure Of Human G[alpha]i1 Bound To The Goloco Motif Of Rgs14

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Guanine nucleotide-binding protein G(i), alpha-1 subunitpolymer32537159.32UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B, D
(B, D)
Regulator of G-protein signalling 14 GoLoco motif peptidepolymer364093.62UniProt (Q506M1)
Pfam (PF02188)
UniProt (by SIFTS) (O43566)
3E, G
(A, C)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4F, H
(A, C)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
5I, J, K, L
(A, B, C, D)
waterwater18.0286Chemie (HOH)
Sequence modifications
A, C: 31 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Gly 30-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight82505.9
Non-Polymers*Number of molecules4
Total formula weight935.0
All*Total formula weight83440.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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