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2OM2

Crystal Structure Of Human G[alpha]i1 Bound To The Goloco Motif Of Rgs14

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Guanine nucleotide-binding protein G(i), alpha-1 subunitpolymer32537159.32UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B, D
(B, D)
Regulator of G-protein signalling 14 GoLoco motif peptidepolymer364093.62UniProt (Q506M1)
Pfam (PF02188)
UniProt (by SIFTS) (O43566)
3E, G
(A, C)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
PubChem (888)
4F, H
(A, C)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
5I, J, K, L
(A, B, C, D)
waterwater18.0286Chemie (HOH)
Sequence modifications
A, C: 31 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Gly 30-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight82505.9
Non-Polymers*Number of molecules4
Total formula weight935.0
All*Total formula weight83440.9
*Water molecules are not included.

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PDB entries from 2026-05-13

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