4FID

Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1

Summary for 4FID

DescriptorG protein alpha subunit, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywordsras-like domain, all-helical domain, gtp binding, nucleotide binding, signaling protein, transducer, lipoprotein, reductive methylation
Biological sourceEntamoeba histolytica
Total number of polymer chains2
Total molecular weight78178.31
Authors
Bosch, D.E.,Kimple, A.J.,Muller, R.E.,Gigure, P.M.,Willard, F.S.,Machius, M.,Temple, B.R.,Siderovski, D.P. (deposition date: 2012-06-08, release date: 2012-11-28, Last modification date: 2013-06-26)
Primary citation
Bosch, D.E.,Kimple, A.J.,Muller, R.E.,Giguere, P.M.,Machius, M.,Willard, F.S.,Temple, B.R.,Siderovski, D.P.
Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica.
Plos Pathog., 8:e1003040-e1003040, 2012
PubMed: 23166501 (PDB entries with the same primary citation)
DOI: 10.1371/journal.ppat.1003040
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.62 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.259150.5%4.8%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4fid
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Molmil generated image of 4fid
rotated about x axis by 90°
Molmil generated image of 4fid
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 4fid
no rotation
Molmil generated image of 4fid
rotated about x axis by 90°
Molmil generated image of 4fid
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4fid.pdb2.gz [102.45 KB])
Coordinate files for Biological unit (4fid.pdb1.gz [107.17 KB])