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4FID

Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001664molecular_functionG protein-coupled receptor binding
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005834cellular_componentheterotrimeric G-protein complex
A0007165biological_processsignal transduction
A0007186biological_processG protein-coupled receptor signaling pathway
A0007188biological_processadenylate cyclase-modulating G protein-coupled receptor signaling pathway
A0007264biological_processsmall GTPase-mediated signal transduction
A0019001molecular_functionguanyl nucleotide binding
A0030154biological_processcell differentiation
A0031683molecular_functionG-protein beta/gamma-subunit complex binding
A0043327biological_processchemotaxis to cAMP
B0000166molecular_functionnucleotide binding
B0001664molecular_functionG protein-coupled receptor binding
B0003924molecular_functionGTPase activity
B0003925molecular_functionG protein activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005834cellular_componentheterotrimeric G-protein complex
B0007165biological_processsignal transduction
B0007186biological_processG protein-coupled receptor signaling pathway
B0007188biological_processadenylate cyclase-modulating G protein-coupled receptor signaling pathway
B0007264biological_processsmall GTPase-mediated signal transduction
B0019001molecular_functionguanyl nucleotide binding
B0030154biological_processcell differentiation
B0031683molecular_functionG-protein beta/gamma-subunit complex binding
B0043327biological_processchemotaxis to cAMP
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE GDP A 401
ChainResidue
AGLY32
AARG163
ATHR164
AASN254
ALYS255
AASP257
ALEU258
AASN326
AALA327
ATHR328
AGLU33
AGLY35
ALYS36
ASER37
ATHR38
AILE160
AHIS161
AASN162

site_idAC2
Number of Residues20
DetailsBINDING SITE FOR RESIDUE GDP B 401
ChainResidue
BGLY32
BGLU33
BSER34
BGLY35
BLYS36
BSER37
BTHR38
BCYS136
BILE160
BHIS161
BARG163
BTHR166
BASN254
BLYS255
BASP257
BLEU258
BASN326
BALA327
BTHR328
BHOH506

218500

PDB entries from 2024-04-17

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