4FID

Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001664	molecular_function	G protein-coupled receptor binding
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0007165	biological_process	signal transduction
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0007188	biological_process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
A	0019001	molecular_function	guanyl nucleotide binding
A	0031683	molecular_function	G-protein beta/gamma-subunit complex binding
B	0001664	molecular_function	G protein-coupled receptor binding
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0007165	biological_process	signal transduction
B	0007186	biological_process	G protein-coupled receptor signaling pathway
B	0007188	biological_process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
B	0019001	molecular_function	guanyl nucleotide binding
B	0031683	molecular_function	G-protein beta/gamma-subunit complex binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GDP A 401

Chain	Residue
A	GLY32
A	ARG163
A	THR164
A	ASN254
A	LYS255
A	ASP257
A	LEU258
A	ASN326
A	ALA327
A	THR328
A	GLU33
A	GLY35
A	LYS36
A	SER37
A	THR38
A	ILE160
A	HIS161
A	ASN162

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site_id	AC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GDP B 401

Chain	Residue
B	GLY32
B	GLU33
B	SER34
B	GLY35
B	LYS36
B	SER37
B	THR38
B	CYS136
B	ILE160
B	HIS161
B	ARG163
B	THR166
B	ASN254
B	LYS255
B	ASP257
B	LEU258
B	ASN326
B	ALA327
B	THR328
B	HOH506

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