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PDB: 139 results

2HEL
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BU of 2hel by Molmil
Crystal structure of a mutant EphA4 kinase domain (Y742A)
Descriptor: Eph receptor A4
Authors:Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
Deposit date:2006-06-21
Release date:2007-02-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.
EMBO J., 25, 2006
3TWS
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BU of 3tws by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human TERF1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWV
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BU of 3twv by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWR
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BU of 3twr by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human 3BP2
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SH3 domain-binding protein 2, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWT
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BU of 3twt by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, NONAETHYLENE GLYCOL, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
4KSJ
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BU of 4ksj by Molmil
Crystal structure of the OTU domain of Gumby/Fam105B at 1.6 angstrom
Descriptor: BETA-MERCAPTOETHANOL, GLYCEROL, Protein FAM105B
Authors:Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4K25
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BU of 4k25 by Molmil
Crystal Structure of yeast Qri7 homodimer
Descriptor: CALCIUM ION, Probable tRNA threonylcarbamoyladenosine biosynthesis protein QRI7, mitochondrial, ...
Authors:Neculai, D, Wan, L, Mao, D.Y, Sicheri, F.
Deposit date:2013-04-08
Release date:2013-05-08
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.
Nucleic Acids Res., 41, 2013
3TWQ
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BU of 3twq by Molmil
Crystal structure of ARC4 from human Tankyrase 2 (apo form)
Descriptor: GLYCEROL, SULFATE ION, Tankyrase-2
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWW
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BU of 3tww by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human LNPEP (chimeric peptide)
Descriptor: SULFATE ION, Tankyrase-2, human LNPEP
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWX
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BU of 3twx by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWU
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BU of 3twu by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Tankyrase-2
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TZM
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BU of 3tzm by Molmil
TGF-beta Receptor type 1 in complex with SB431542
Descriptor: 4-[5-(1,3-benzodioxol-5-yl)-4-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide, TGF-beta receptor type-1
Authors:Ogunjimi, A.A, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
Deposit date:2011-09-27
Release date:2012-05-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Specificity of TGFbeta Family Receptor Small Molecule Inhibitors
Cell Signal, 24, 2012
2QGX
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BU of 2qgx by Molmil
Ubiquitin-conjugating enzyme E2Q
Descriptor: Ubiquitin-conjugating enzyme E2 Q1
Authors:Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-06-29
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2OB4
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BU of 2ob4 by Molmil
Human Ubiquitin-Conjugating Enzyme CDC34
Descriptor: Ubiquitin-conjugating enzyme E2-32 kDa complementing
Authors:Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-12-18
Release date:2006-12-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012

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