4UBD
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![BU of 4ubd by Molmil](/molmil-images/mine/4ubd) | Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | Authors: | Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J. | Deposit date: | 2014-08-12 | Release date: | 2015-06-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus. Nat Commun, 6, 2015
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6B3M
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![BU of 6b3m by Molmil](/molmil-images/mine/6b3m) | The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 70-1F02 Fab Heavy Chain, ... | Authors: | Shore, D.A, Yang, H, Stevens, J. | Deposit date: | 2017-09-22 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.92 Å) | Cite: | Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. J. Virol., 92, 2018
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3B9K
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![BU of 3b9k by Molmil](/molmil-images/mine/3b9k) | Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab Light Chain, ... | Authors: | Shore, D, Wilson, I.A. | Deposit date: | 2007-11-05 | Release date: | 2008-11-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I J.Mol.Biol., 384, 2008
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2ARJ
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![BU of 2arj by Molmil](/molmil-images/mine/2arj) | CD8alpha-alpha in complex with YTS 105.18 Fab | Descriptor: | T-cell surface glycoprotein CD8 alpha chain, YTS 105.18 antigen binding region Heavy chain, YTS 105.18 antigen binding region Light chain | Authors: | Shore, D.A, Teyton, L, Dwek, R.A, Rudd, P.M, Wilson, I.A. | Deposit date: | 2005-08-19 | Release date: | 2006-05-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution. J.Mol.Biol., 358, 2006
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3R06
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![BU of 3r06 by Molmil](/molmil-images/mine/3r06) | |
3R08
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![BU of 3r08 by Molmil](/molmil-images/mine/3r08) | Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab | Descriptor: | Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, Mouse anti-mouse CD3epsilon antibody 2C11 light chain, T-cell surface glycoprotein CD3 epsilon chain | Authors: | Shore, D.A, Zhu, X, Wilson, I.A. | Deposit date: | 2011-03-07 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements. J.Biol.Chem., 287, 2012
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4KW1
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![BU of 4kw1 by Molmil](/molmil-images/mine/4kw1) | Structure of a/egypt/n03072/2010 h5 ha | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Shore, D.A, Yang, H, Carney, P.J, Chang, J.C, Stevens, J. | Deposit date: | 2013-05-23 | Release date: | 2014-06-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and antigenic variation among diverse clade 2 H5N1 viruses. Plos One, 8, 2013
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4KTH
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![BU of 4kth by Molmil](/molmil-images/mine/4kth) | Structure of A/Hubei/1/2010 H5 HA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Shore, D.A, Yang, H, Carney, P.J, Chang, J.C, Stevens, J. | Deposit date: | 2013-05-20 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Antigenic Variation among Diverse Clade 2 H5N1 Viruses. Plos One, 8, 2013
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4QNP
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![BU of 4qnp by Molmil](/molmil-images/mine/4qnp) | Crystal structure of the 2009 pandemic H1N1 influenza virus neuraminidase with a neutralizing antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wan, H.Q, Yang, H, Shore, D.A, Garten, R.J, Couzens, L, Gao, J, Jiang, L.L, Carney, P.J, Villanueva, J, Stevens, J, Eichelberger, M.C. | Deposit date: | 2014-06-18 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers. Nat Commun, 6, 2015
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4LXV
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![BU of 4lxv by Molmil](/molmil-images/mine/4lxv) | Crystal Structure of the Hemagglutinin from a H1N1pdm A/WASHINGTON/5/2011 virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Yang, H, Chang, J.C, Guo, Z, Carney, P.J, Shore, D.A, Donis, R.O, Cox, N.J, Villanueva, J.M, Klimov, A.I, Stevens, J. | Deposit date: | 2013-07-30 | Release date: | 2014-02-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins. J.Virol., 88, 2014
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4KWM
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![BU of 4kwm by Molmil](/molmil-images/mine/4kwm) | Structure of a/anhui/5/2005 h5 ha | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Yang, H, Shore, D.A, Carney, P.J, Chang, J.C, Stevens, J. | Deposit date: | 2013-05-24 | Release date: | 2014-06-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and antigenic variation among diverse clade 2 H5N1 viruses. Plos One, 8, 2013
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7LTG
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![BU of 7ltg by Molmil](/molmil-images/mine/7ltg) | STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH APICIDIN | Descriptor: | (3S,6S,9S,15aR)-9-[(2S)-butan-2-yl]-3-(6,6-dihydroxyoctyl)-6-[(1-methoxy-1H-indol-3-yl)methyl]octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Klein, D.J, Beshore, D.C. | Deposit date: | 2021-02-19 | Release date: | 2021-05-05 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. Acs Med.Chem.Lett., 12, 2021
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7LTK
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![BU of 7ltk by Molmil](/molmil-images/mine/7ltk) | |
7LTL
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![BU of 7ltl by Molmil](/molmil-images/mine/7ltl) | |