PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN INHIBITOR THAT LACKS A ZINC BINDING GROUP (COMPOUND 12)
Descriptor:	ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:	Klein, D.J, Beshore, D.C.
Deposit date:	2021-02-19
Release date:	2021-05-05
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.59 Å)
Cite:	Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. Acs Med.Chem.Lett., 12, 2021

STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN INHIBITOR LACKING A ZINC BINDING GROUP (COMPOUND 19)
Descriptor:	(2R)-2-(5-hydroxy-2-methyl-1H-indol-3-yl)-N-{(1S)-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]pentyl}propanamide, ACETATE ION, CALCIUM ION, ...
Authors:	Klein, D.J, Beshore, D.C.
Deposit date:	2021-02-19
Release date:	2021-05-05
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.49 Å)
Cite:	Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. Acs Med.Chem.Lett., 12, 2021

STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH APICIDIN
Descriptor:	(3S,6S,9S,15aR)-9-[(2S)-butan-2-yl]-3-(6,6-dihydroxyoctyl)-6-[(1-methoxy-1H-indol-3-yl)methyl]octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:	Klein, D.J, Beshore, D.C.
Deposit date:	2021-02-19
Release date:	2021-05-05
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. Acs Med.Chem.Lett., 12, 2021