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PDB: 829 件

5ZAB
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Crystal structure of cf3-aequorin
分子名称: (2S)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-{[4-(trifluoromethyl)phenyl]methyl}imidazo[1,2-a]pyrazin-3(2H)-one, Aequorin-2
著者Inouye, S, Tomabechi, Y, Sekine, S.I, Shirouzu, M, Hosoya, T.
登録日2018-02-07
公開日2018-06-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin.
J. Biochem., 164, 2018
6KS0
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Crystal structure of the human adiponectin receptor 1
分子名称: Adiponectin receptor protein 1, PHOSPHATE ION, The heavy chain variable domain (Antibody), ...
著者Tanabe, H, Fujii, Y, Nakamura, Y, Hosaka, T, Okada-Iwabu, M, Iwabu, M, Kimura-Someya, T, Shirouzu, M, Yamauchi, T, Kadowaki, T, Yokoyama, S.
登録日2019-08-22
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Human adiponectin receptor AdipoR1 assumes closed and open structures.
Commun Biol, 3, 2020
6KS1
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Crystal structure of the human adiponectin receptor 2
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, ...
著者Tanabe, H, Fujii, Y, Nakamura, Y, Hosaka, T, Okada-Iwabu, M, Iwabu, M, Kimura-Someya, T, Shirouzu, M, Yamauchi, T, Kadowaki, T, Yokoyama, S.
登録日2019-08-22
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Human adiponectin receptor AdipoR1 assumes closed and open structures.
Commun Biol, 3, 2020
7X8Z
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab188
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab188 heavy chain, Ab188 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X91
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The SARS-CoV-2 receptor binding domain bound with an Fv-clasp form of a human neutralizing antibody Ab496
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, An Fv-clasp version of the Ab496 heavy chain, An Fv-clasp version of the Ab496 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
6JPP
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Solution structure of ELMO1 RBD
分子名称: Engulfment and cell motility protein 1
著者Tsuda, K, Kukimoto-Niino, M, Shirouzu, M.
登録日2019-03-27
公開日2020-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Commun Biol, 6, 2023
7X94
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab712
分子名称: Ab712 heavy chain, Ab712 light chain, Spike glycoprotein, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
5YZA
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Crystal Structure of Human CRMP-2 with S522D mutation
分子名称: Dihydropyrimidinase-related protein 2
著者Sumi, T, Imasaki, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R.
登録日2017-12-13
公開日2018-03-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Altering Function of CRMP2 by Phosphorylation.
Cell Struct. Funct., 43, 2018
5YZ5
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Crystal Structure of Human CRMP-2 with T509D-T514D-S518D-S522D mutations
分子名称: Dihydropyrimidinase-related protein 2, SULFATE ION
著者Imasaki, T, Sumi, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R.
登録日2017-12-13
公開日2018-03-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Insights into the Altering Function of CRMP2 by Phosphorylation.
Cell Struct. Funct., 43, 2018
5YZB
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Crystal Structure of Human CRMP-2 with S522D-T509D-T514D-S518D mutations crystallized with GSK3b
分子名称: Dihydropyrimidinase-related protein 2
著者Imasaki, T, Sumi, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R.
登録日2017-12-13
公開日2018-03-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Insights into the Altering Function of CRMP2 by Phosphorylation.
Cell Struct. Funct., 43, 2018
7X95
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab709
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab709 heavy chain, Ab709 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7X93
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab765
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab765 heavy chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7X96
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BU of 7x96 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab847
分子名称: Ab847 heavy chain, Ab847 light chain, Spike glycoprotein, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
6IP8
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Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
登録日2018-11-02
公開日2019-05-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
7Y6L
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab816
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab816 heavy chain, Ab816 light chain, ...
著者Uchikubo, T, Shirouzu, M.
登録日2022-06-21
公開日2023-06-21
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
7Y6N
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BU of 7y6n by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab803
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab803 heavy chain, Ab803 light chain, ...
著者Uchikubo, T, Shirouzu, M.
登録日2022-06-21
公開日2023-06-21
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Iscience, 26, 2023
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
登録日2018-11-02
公開日2019-05-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
7VA9
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BU of 7va9 by Molmil
Rba sphaeroides PufY-KO RC-LH1 dimer type-1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN B, ...
著者Bracun, L, Yamagata, A, Liu, L.N, Shirouzu, M.
登録日2021-08-27
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural basis for the assembly and quinone transport mechanisms of the dimeric photosynthetic RC-LH1 supercomplex.
Nat Commun, 13, 2022
7VB9
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Rba sphaeroides PufY-KO RC-LH1 dimer type-2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ...
著者Bracun, L, Yamagata, A, Liu, L.N, Shirouzu, M.
登録日2021-08-30
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis for the assembly and quinone transport mechanisms of the dimeric photosynthetic RC-LH1 supercomplex.
Nat Commun, 13, 2022
6IP5
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BU of 6ip5 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
登録日2018-11-02
公開日2019-05-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
7X8Y
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BU of 7x8y by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab159
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab159 heavy chain, Ab159 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X92
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab445
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab445 heavy chain, Ab445 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X90
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab326
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab326 heavy chain, Ab326 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8W
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The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab354
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab354 heavy chain, Ab354 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
6KRO
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Tankyrase-2 in complex with RK-582
分子名称: 6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-fluoranyl-1-methyl-1'-(8-methyl-4-oxidanylidene-3,5,6,7-tetrahydropyrido[2,3-d]pyrimidin-2-yl)spiro[indole-3,4'-piperidine]-2-one, GLYCEROL, PHOSPHATE ION, ...
著者Niwa, H, Shirai, F, Sato, S, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
登録日2019-08-22
公開日2020-04-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.
J.Med.Chem., 63, 2020

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件を2024-06-12に公開中

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