2DYP
 
 | | Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G | | 分子名称: | 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K. | | 登録日 | 2006-09-15 | | 公開日 | 2006-11-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1C08
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN LYSOZYME COMPLEX | | 分子名称: | ANTI-HEN EGG WHITE LYSOZYME ANTIBODY (HYHEL-10), LYSOZYME | | 著者 | Shiroishi, M, Kondo, H, Matsushima, M, Tsumoto, K, Kumagai, I. | | 登録日 | 1999-07-15 | | 公開日 | 2000-07-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces.
J.Biol.Chem., 274, 1999
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1UGN
 | | Crystal structure of LIR1.02, one of the alleles of LIR1 | | 分子名称: | Leukocyte immunoglobulin-like receptor 1 | | 著者 | Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K. | | 登録日 | 2003-06-17 | | 公開日 | 2004-08-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis.
Hum.Mol.Genet., 14, 2005
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1VDG
 | | Crystal structure of LIR1.01, one of the alleles of LIR1 | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily B member 1 | | 著者 | Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K. | | 登録日 | 2004-03-22 | | 公開日 | 2005-08-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of LIR1.03, one of the alleles of LIR1
To be Published
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5Y25
 | | EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062 | | 分子名称: | (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor | | 著者 | Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A. | | 登録日 | 2017-07-24 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | | 主引用文献 | Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.
Nat.Chem.Biol., 15, 2019
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1UFU
 | | Crystal structure of ligand binding domain of immunoglobulin-like transcript 2 (ILT2; LIR-1) | | 分子名称: | Immunoglobulin-like transcript 2 | | 著者 | Shiroishi, M, Amano, K, Rasubala, L, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K. | | 登録日 | 2003-06-10 | | 公開日 | 2004-08-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Kinetic and thermodynamic properties of the interaction between Immunoglobulin like transcript (ILT) and MHC class I
To be Published
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5XMH
 | | Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, ... | | 著者 | Shiroishi, M, Shimokawa, K, Lee, J.M, Kusakabe, M, Ueda, T. | | 登録日 | 2017-05-15 | | 公開日 | 2018-03-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity.
J. Biol. Chem., 293, 2018
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1IC4
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX | | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | 登録日 | 2001-03-30 | | 公開日 | 2001-07-18 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
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1IC7
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX | | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | 登録日 | 2001-03-30 | | 公開日 | 2001-07-18 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
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1IC5
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX | | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | 登録日 | 2001-03-30 | | 公開日 | 2001-07-18 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
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2D3V
 | | Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11) | | 分子名称: | leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1 | | 著者 | Shiroishi, M, Kajikawa, M, Kuroki, K, Ose, T, Kohda, D, Maenaka, K. | | 登録日 | 2005-10-03 | | 公開日 | 2006-06-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of the human monocyte-activating receptor,
J.Biol.Chem., 281, 2006
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2D31
 | | Crystal structure of disulfide-linked HLA-G dimer | | 分子名称: | 9-mer peptide from Histone H2A, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Shiroishi, M, Kuroki, K, Ose, T, Rasubala, L, Shiratori, I, Arase, H, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K. | | 登録日 | 2005-09-23 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer
J.Biol.Chem., 281, 2006
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2DQI
 | | Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-26 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQF
 | | Crystal structure of hyhel-10 FV mutant (y33ay53a) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-25 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQG
 | | Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-25 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQC
 | | Crystal structure of hyhel-10 FV mutant(Hy33f) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-25 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQD
 | | Crystal structure of hyhel-10 FV mutant (Hy50f) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-25 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQH
 | | Crystal structure of hyhel-10 FV mutant (Hy58a) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-26 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQE
 | | Crystal structure of hyhel-10 FV mutant (Hy53a) complexed with hen egg lysozyme | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-25 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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2DQJ
 | | Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | | 登録日 | 2006-05-26 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
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6K60
 | | Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain G, ... | | 著者 | Kuroki, K, Matsubara, H, Kanda, R, Miyashita, N, Shiroishi, M, Fukunaga, Y, Kamishikiryo, J, Fukunaga, A, Hirose, K, Sugita, Y, Kita, S, Ose, T, Maenaka, K. | | 登録日 | 2019-05-31 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.149 Å) | | 主引用文献 | Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms.
J Immunol., 203, 2019
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3UON
 | | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist | | 分子名称: | (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, CHLORIDE ION, Human M2 muscarinic acetylcholine, ... | | 著者 | Haga, K, Kruse, A.C, Asada, H, Yurugi-Kobayashi, T, Shiroishi, M, Zhang, C, Weis, W.I, Okada, T, Kobilka, B.K, Haga, T, Kobayashi, T. | | 登録日 | 2011-11-16 | | 公開日 | 2012-02-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Nature, 482, 2012
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3RZE
 | | Structure of the human histamine H1 receptor in complex with doxepin | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, (3Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ... | | 著者 | Shimamura, T, Han, G.W, Shiroishi, M, Weyand, S, Tsujimoto, H, Winter, G, Katritch, V, Abagyan, R, Cherezov, V, Liu, W, Kobayashi, T, Stevens, R, Iwata, S, GPCR Network (GPCR) | | 登録日 | 2011-05-11 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
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3A67
 | | Crystal Structure of HyHEL-10 Fv mutant LN31D complexed with hen egg white lysozyme | | 分子名称: | IG VH, anti-lysozyme, Lysozyme C, ... | | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I. | | 登録日 | 2009-08-24 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010
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3A6C
 | | Crystal Structure of HyHEL-10 Fv mutant LN92D complexed with hen egg white lysozyme | | 分子名称: | IG VH, anti-lysozyme, Lysozyme C, ... | | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I. | | 登録日 | 2009-08-28 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010
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