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PDB: 31 件
1C08
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CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN LYSOZYME COMPLEX
分子名称: ANTI-HEN EGG WHITE LYSOZYME ANTIBODY (HYHEL-10), LYSOZYME
著者Shiroishi, M, Kondo, H, Matsushima, M, Tsumoto, K, Kumagai, I.
登録日1999-07-15
公開日2000-07-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces.
J.Biol.Chem., 274, 1999
1VDG
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Crystal structure of LIR1.01, one of the alleles of LIR1
分子名称: Leukocyte immunoglobulin-like receptor subfamily B member 1
著者Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K.
登録日2004-03-22
公開日2005-08-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of LIR1.03, one of the alleles of LIR1
To be Published
1UGN
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Crystal structure of LIR1.02, one of the alleles of LIR1
分子名称: Leukocyte immunoglobulin-like receptor 1
著者Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K.
登録日2003-06-17
公開日2004-08-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis.
Hum.Mol.Genet., 14, 2005
1UFU
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Crystal structure of ligand binding domain of immunoglobulin-like transcript 2 (ILT2; LIR-1)
分子名称: Immunoglobulin-like transcript 2
著者Shiroishi, M, Amano, K, Rasubala, L, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K.
登録日2003-06-10
公開日2004-08-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Kinetic and thermodynamic properties of the interaction between Immunoglobulin like transcript (ILT) and MHC class I
To be Published
5Y25
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EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062
分子名称: (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor
著者Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A.
登録日2017-07-24
公開日2018-07-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.
Nat.Chem.Biol., 15, 2019
5XMH
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Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, ...
著者Shiroishi, M, Shimokawa, K, Lee, J.M, Kusakabe, M, Ueda, T.
登録日2017-05-15
公開日2018-03-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity.
J. Biol. Chem., 293, 2018
1IC4
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CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX
分子名称: IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C
著者Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I.
登録日2001-03-30
公開日2001-07-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
1IC7
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CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX
分子名称: IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C
著者Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I.
登録日2001-03-30
公開日2001-07-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
1IC5
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CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX
分子名称: IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C
著者Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I.
登録日2001-03-30
公開日2001-07-18
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
2DYP
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Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G
分子名称: 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K.
登録日2006-09-15
公開日2006-11-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Proc.Natl.Acad.Sci.Usa, 103, 2006
2D3V
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Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)
分子名称: leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1
著者Shiroishi, M, Kajikawa, M, Kuroki, K, Ose, T, Kohda, D, Maenaka, K.
登録日2005-10-03
公開日2006-06-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the human monocyte-activating receptor,
J.Biol.Chem., 281, 2006
2D31
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Crystal structure of disulfide-linked HLA-G dimer
分子名称: 9-mer peptide from Histone H2A, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Shiroishi, M, Kuroki, K, Ose, T, Rasubala, L, Shiratori, I, Arase, H, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K.
登録日2005-09-23
公開日2006-03-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer
J.Biol.Chem., 281, 2006
2DQI
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Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-26
公開日2007-01-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQF
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Crystal structure of hyhel-10 FV mutant (y33ay53a) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-25
公開日2007-01-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQG
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Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-25
公開日2007-01-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQD
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Crystal structure of hyhel-10 FV mutant (Hy50f) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-25
公開日2007-01-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQC
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Crystal structure of hyhel-10 FV mutant(Hy33f) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-25
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQH
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Crystal structure of hyhel-10 FV mutant (Hy58a) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-26
公開日2007-01-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQE
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Crystal structure of hyhel-10 FV mutant (Hy53a) complexed with hen egg lysozyme
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-25
公開日2007-01-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
2DQJ
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Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution
分子名称: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
著者Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
登録日2006-05-26
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
6K60
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Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain G, ...
著者Kuroki, K, Matsubara, H, Kanda, R, Miyashita, N, Shiroishi, M, Fukunaga, Y, Kamishikiryo, J, Fukunaga, A, Hirose, K, Sugita, Y, Kita, S, Ose, T, Maenaka, K.
登録日2019-05-31
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.149 Å)
主引用文献Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms.
J Immunol., 203, 2019
5WQV
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Crystal structure of PriB mutant - S55A
分子名称: Primosomal replication protein N
著者Fujiyama, S, Shiroishi, M, Katayama, T, Abe, Y, Ueda, T.
登録日2016-11-28
公開日2017-11-29
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Insight into the interaction between PriB and DnaT on bacterial DNA replication restart: Significance of the residues on PriB dimer interface and highly acidic region on DnaT.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
3UON
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Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
分子名称: (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, CHLORIDE ION, Human M2 muscarinic acetylcholine, ...
著者Haga, K, Kruse, A.C, Asada, H, Yurugi-Kobayashi, T, Shiroishi, M, Zhang, C, Weis, W.I, Okada, T, Kobilka, B.K, Haga, T, Kobayashi, T.
登録日2011-11-16
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Nature, 482, 2012
3RZE
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Structure of the human histamine H1 receptor in complex with doxepin
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, (3Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ...
著者Shimamura, T, Han, G.W, Shiroishi, M, Weyand, S, Tsujimoto, H, Winter, G, Katritch, V, Abagyan, R, Cherezov, V, Liu, W, Kobayashi, T, Stevens, R, Iwata, S, GPCR Network (GPCR)
登録日2011-05-11
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
3A67
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Crystal Structure of HyHEL-10 Fv mutant LN31D complexed with hen egg white lysozyme
分子名称: IG VH, anti-lysozyme, Lysozyme C, ...
著者Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I.
登録日2009-08-24
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010

 

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