Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 16 件
7D24
DownloadVisualize
BU of 7d24 by Molmil
Hsp90 alpha N-terminal domain in complex with a 4B compund
分子名称: 9-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-6-chloranyl-purin-2-amine, Heat shock protein HSP 90-alpha
著者Shin, S.C, Kim, E.E.
登録日2020-09-15
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Int J Mol Sci, 21, 2020
7D26
DownloadVisualize
BU of 7d26 by Molmil
Hsp90 alpha N-terminal domain in complex with a 8 compund
分子名称: 6-chloranyl-9-[(2-phenyl-1,3-oxazol-5-yl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha
著者Shin, S.C, Kim, E.E.
登録日2020-09-15
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Int J Mol Sci, 21, 2020
7D22
DownloadVisualize
BU of 7d22 by Molmil
Hsp90 alpha N-terminal domain in complex with a 6B compund
分子名称: 9-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-6-chloranyl-purin-2-amine, Heat shock protein HSP 90-alpha
著者Shin, S.C, Kim, E.E.
登録日2020-09-15
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Int J Mol Sci, 21, 2020
7D1V
DownloadVisualize
BU of 7d1v by Molmil
Hsp90 alpha N-terminal domain in complex with a 6C compund
分子名称: 6-chloranyl-9-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha
著者Shin, S.C, Kim, E.E.
登録日2020-09-15
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.332 Å)
主引用文献Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Int J Mol Sci, 21, 2020
7D25
DownloadVisualize
BU of 7d25 by Molmil
Hsp90 alpha N-terminal domain in complex with a 14 compund
分子名称: 6-chloranyl-9-[(4-methylphenyl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha
著者Shin, S.C, Kim, E.E.
登録日2020-09-15
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Int J Mol Sci, 21, 2020
7TBA
DownloadVisualize
BU of 7tba by Molmil
Pentraxin - ligand complex
分子名称: C-reactive protein, CALCIUM ION, [3-(dibutylamino)propyl]phosphonic acid
著者Shing, K.S.C.T, Morton, C.J, Parker, M.W.
登録日2021-12-21
公開日2022-10-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
Embo Mol Med, 15, 2023
8ITN
DownloadVisualize
BU of 8itn by Molmil
Crystal structure of USP47apo catalytic domain
分子名称: Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION
著者Kim, E.E, Shin, S.C.
登録日2023-03-22
公開日2024-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional characterization of USP47 reveals a hot spot for inhibitor design.
Commun Biol, 6, 2023
8ITP
DownloadVisualize
BU of 8itp by Molmil
Crystal structure of USP47 catalytic domain complex with ubiquitin
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION
著者Kim, E.E, Shin, S.C.
登録日2023-03-22
公開日2024-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional characterization of USP47 reveals a hot spot for inhibitor design.
Commun Biol, 6, 2023
7FGN
DownloadVisualize
BU of 7fgn by Molmil
The crystal structure of the FAF1 UBL1
分子名称: FAS-associated factor 1
著者Kim, E.E, ParK, J.K, Shin, S.C.
登録日2021-07-27
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
J Mol Cell Biol, 14, 2022
7FGM
DownloadVisualize
BU of 7fgm by Molmil
The complex crystals structure of the FAF1 UBL1_L-Hsp70 NBD with ADP and phosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, FAS-associated factor 1, Heat shock 70 kDa protein 1A, ...
著者Kim, E.E, ParK, J.K, Shin, S.C.
登録日2021-07-27
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
J Mol Cell Biol, 14, 2022
5GVJ
DownloadVisualize
BU of 5gvj by Molmil
Structure of FabK (M276A) mutant from Thermotoga maritima
分子名称: Enoyl-[acyl-carrier-protein] reductase [FMN], SODIUM ION
著者Kim, E.E, Shin, S.C, Ha, B.H, Moon, J.H.
登録日2016-09-06
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and biochemical characterization of FabK from Thermotoga maritima.
Biochem. Biophys. Res. Commun., 482, 2017
5GVH
DownloadVisualize
BU of 5gvh by Molmil
Structure of FabK from Thermotoga maritima
分子名称: Enoyl-[acyl-carrier-protein] reductase [FMN], FLAVIN MONONUCLEOTIDE, SODIUM ION
著者Kim, E.E, Shin, S.C, Ha, B.H, Moon, J.H.
登録日2016-09-05
公開日2017-06-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Structural and biochemical characterization of FabK from Thermotoga maritima.
Biochem. Biophys. Res. Commun., 482, 2017
5H22
DownloadVisualize
BU of 5h22 by Molmil
Hsp90 alpha N-terminal domain in complex with an inhibitor
分子名称: 4-chloranyl-7-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl]-5-(phenylmethyl)pyrrolo[2,3-d]pyrimidin-2-amine, Hsp90aa1 protein
著者Kim, E.E, Shin, S.C, Keum, G.C.
登録日2016-10-13
公開日2017-10-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5X3S
DownloadVisualize
BU of 5x3s by Molmil
Crystal structure of mouse Plk1-PBD in complex with phosphopeptide from HEF1 (799-809)
分子名称: Peptide from Enhancer of filamentation 1, Serine/threonine-protein kinase PLK1
著者Kim, J.H, Shin, S.C, Kim, E.E.
登録日2017-02-07
公開日2017-12-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.
J. Biol. Chem., 293, 2018
5ZQM
DownloadVisualize
BU of 5zqm by Molmil
Crystal structure of human katanin AAA ATPase domain complex with ATPgammaS
分子名称: Katanin p60 ATPase-containing subunit A1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Kim, E.E, Shin, S.C.
登録日2018-04-19
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Molecular Basis for Katanin-Mediated Severing of Glutamylated Microtubules.
Cell Rep, 26, 2019
5ZQL
DownloadVisualize
BU of 5zql by Molmil
crystal structure of human katanin AAA ATPase domain
分子名称: Katanin p60 ATPase-containing subunit A1
著者Kim, E.E, Shin, S.C.
登録日2018-04-19
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.007 Å)
主引用文献Structural and Molecular Basis for Katanin-Mediated Severing of Glutamylated Microtubules.
Cell Rep, 26, 2019

223166

件を2024-07-31に公開中

PDB statisticsPDBj update infoContact PDBjnumon