5KL7
 
 | | Wilms Tumor Protein (WT1) ZnF2-4Q369R in complex with carboxylated DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | | 著者 | Hashimoto, H, Cheng, X. | | 登録日 | 2016-06-23 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.579 Å) | | 主引用文献 | Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
|
|
8HN3
 | | Soluble domain of cytochrome c-556 from Chlorobaculum tepidum | | 分子名称: | ACETATE ION, Cytochrome c-556, GLYCEROL, ... | | 著者 | Kishimoto, H, Azai, C, Yamamoto, T, Mutoh, R, Nakaniwa, T, Tanaka, H, Kurisu, G, Oh-oka, H. | | 登録日 | 2022-12-07 | | 公開日 | 2023-07-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Soluble domains of cytochrome c-556 and Rieske iron-sulfur protein from Chlorobaculum tepidum: Crystal structures and interaction analysis.
Curr Res Struct Biol, 5, 2023
|
|
6DNZ
 | | Trypanosoma brucei PRMT1 enzyme-prozyme heterotetrameric complex with AdoHcy | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arginine N-methyltransferase, putative, ... | | 著者 | Hashimoto, H, Kafkova, L, Jordan, K, Read, L.K, Debler, E.W. | | 登録日 | 2018-06-08 | | 公開日 | 2019-06-12 | | 最終更新日 | 2020-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.384 Å) | | 主引用文献 | Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme).
J.Mol.Biol., 432, 2020
|
|
8HN2
 | | Selenomethionine-labelled soluble domain of Rieske iron-sulfur protein from chlorobaculum tepidum | | 分子名称: | Cytochrome b6-f complex iron-sulfur subunit, FE2/S2 (INORGANIC) CLUSTER | | 著者 | Kishimoto, H, Mutoh, R, Tanaka, H, Kurisu, G, Oh-oka, H. | | 登録日 | 2022-12-07 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Soluble domains of cytochrome c-556 and Rieske iron-sulfur protein from Chlorobaculum tepidum: Crystal structures and interaction analysis.
Curr Res Struct Biol, 5, 2023
|
|
5ZHX
 | |
8XGR
 | | ETB-eGt complex bound to endothelin-1 | | 分子名称: | Camelid antibody VHH fragment, Endothelin receptor type B, Endothelin-1, ... | | 著者 | Oshima, H.S, Sano, F.K, Akasaka, H, Iwama, A, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-15 | | 公開日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Optimizing cryo-EM structural analysis of G i -coupling receptors via engineered G t and Nb35 application.
Biochem.Biophys.Res.Commun., 693, 2024
|
|
5T00
 | | Human CTCF ZnF3-7 and methylated DNA complex | | 分子名称: | DNA (5'-GCCAGCAGGGGG(5CM)GCTA-3'), DNA (5'-TAG(5CM)GCCCCCTGCTGGC-3'), Transcriptional repressor CTCF, ... | | 著者 | Hashimoto, H, Wang, D, Cheng, X. | | 登録日 | 2016-08-15 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
|
|
5T0U
 | | CTCF ZnF2-7 and DNA complex structure | | 分子名称: | DNA (5'-D(*CP*CP*TP*CP*AP*CP*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*AP*GP*TP*GP*AP*GP*G)-3'), Transcriptional repressor CTCF, ... | | 著者 | Hashimoto, H, Wang, D, Cheng, X. | | 登録日 | 2016-08-16 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.199 Å) | | 主引用文献 | Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
|
|
2RSO
 | |
3ALR
 | | Crystal structure of Nanos | | 分子名称: | Nanos protein, ZINC ION | | 著者 | Hashimoto, H, Hara, K, Hishiki, A, Kawaguchi, S, Shichijo, N, Nakamura, K, Unzai, S, Tamaru, Y, Shimizu, T, Sato, M. | | 登録日 | 2010-08-06 | | 公開日 | 2011-02-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of zinc-finger domain of Nanos and its functional implications
Embo Rep., 11, 2010
|
|
3G5S
 | | Crystal structure of Thermus thermophilus TrmFO in complex with glutathione | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, ... | | 著者 | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | | 登録日 | 2009-02-05 | | 公開日 | 2009-05-19 | | 最終更新日 | 2011-12-14 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5XGC
 | | Crystal structure of SmgGDS-558 | | 分子名称: | Rap1 GTPase-GDP dissociation stimulator 1 | | 著者 | Shimizu, H, Toma-Fukai, S, Shimizu, T. | | 登録日 | 2017-04-13 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding
J. Biol. Chem., 292, 2017
|
|
3G5R
 | | Crystal structure of Thermus thermophilus TrmFO in complex with tetrahydrofolate | | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, CALCIUM ION, ... | | 著者 | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | | 登録日 | 2009-02-05 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
4LT5
 | | Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA, MANGANESE (II) ION, ... | | 著者 | Hashimoto, H, Pais, J.E, Zhang, X, Saleh, L, Fu, Z.Q, Dai, N, Correa, I.R, Roberts, R.J, Zheng, Y, Cheng, X. | | 登録日 | 2013-07-23 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.893 Å) | | 主引用文献 | Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.
Nature, 506, 2014
|
|
5KE7
 | |
5K5I
 | |
5KE6
 | |
5KEB
 | |
3W69
 | | Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor | | 分子名称: | (5R,6S)-2-[((2S,5R)-2-{[(3R)-4-acetyl-3-methylpiperazin-1-yl]carbonyl}-5-ethylpyrrolidin-1-yl)carbonyl]-5,6-bis(4-chlorophenyl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | | 著者 | Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. | | 登録日 | 2013-02-12 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Synthesis and evaluation of novel orally active p53-MDM2 interaction inhibitors
Bioorg.Med.Chem., 21, 2013
|
|
4GEM
 | | Crystal structure of Zucchini (K171A) | | 分子名称: | 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, ZINC ION | | 著者 | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | | 登録日 | 2012-08-02 | | 公開日 | 2012-10-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
|
|
6AI6
 | | Crystal structure of SpCas9-NG | | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), ... | | 著者 | Nishimasu, H, Hirano, S, Ishitani, R, Nureki, O. | | 登録日 | 2018-08-21 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Engineered CRISPR-Cas9 nuclease with expanded targeting space
Science, 361, 2018
|
|
2RO0
 | | Solution structure of the knotted tudor domain of the yeast histone acetyltransferase, Esa1 | | 分子名称: | Histone acetyltransferase ESA1 | | 著者 | Shimojo, H, Sano, N, Moriwaki, Y, Okuda, M, Horikoshi, M, Nishimura, Y. | | 登録日 | 2008-03-01 | | 公開日 | 2008-04-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Novel structural and functional mode of a knot essential for RNA binding activity of the Esa1 presumed chromodomain
J.Mol.Biol., 378, 2008
|
|
2RNZ
 | | Solution structure of the presumed chromodomain of the yeast histone acetyltransferase, Esa1 | | 分子名称: | Histone acetyltransferase ESA1 | | 著者 | Shimojo, H, Sano, N, Moriwaki, Y, Okuda, M, Horikoshi, M, Nishimura, Y. | | 登録日 | 2008-03-01 | | 公開日 | 2008-04-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Novel structural and functional mode of a knot essential for RNA binding activity of the Esa1 presumed chromodomain
J.Mol.Biol., 378, 2008
|
|
2RSN
 | |
1EHG
 | |
