2PLR
| Crystal structure of dTMP kinase (st1543) from Sulfolobus Tokodaii Strain7 | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Kanaujia, S.P, Jeyakanthan, J, Rafi, Z.A, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-20 | Release date: | 2008-04-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of dTMP kinase (st1543) from Sulfolobus Tokodaii Strain7 To be Published
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2PPY
| Crystal structure of Enoyl-CoA hydrates (gk_1992) from Geobacillus Kaustophilus HTA426 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Enoyl-CoA hydratase | Authors: | Kanaujia, S.P, Jeyakanthan, J, Kavyashree, M, Sekar, K, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-01 | Release date: | 2008-05-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of Enoyl-CoA hydrates (gk_1992) from Geobacillus Kaustophilus HTA426 To be Published
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2PCJ
| Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 | Descriptor: | Lipoprotein-releasing system ATP-binding protein lolD, SULFITE ION | Authors: | Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 To be Published
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2PBR
| Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5 | Descriptor: | SULFATE ION, Thymidylate kinase | Authors: | Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-29 | Release date: | 2007-10-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5 To be Published
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7FFH
| Diarylpentanoid-producing polyketide synthase (N199L mutant) | Descriptor: | Type III polyketide synthase | Authors: | Morita, H, Wong, C.P, Liu, Q, Takeshi, K, Lee, Y, Nakashima, Y. | Deposit date: | 2021-07-23 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood. Nat Commun, 13, 2022
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2ANL
| X-ray crystal structure of the aspartic protease plasmepsin 4 from the malarial parasite plasmodium malariae bound to an allophenylnorstatine based inhibitor | Descriptor: | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide, plasmepsin IV | Authors: | Clemente, J.C, Govindasamy, L, Madabushi, A, Fisher, S.Z, Moose, R.E, Yowell, C.A, Hidaka, K, Kimura, T, Hayashi, Y, Kiso, Y, Agbandje-McKenna, M, Dame, J.B, Dunn, B.M, McKenna, R. | Deposit date: | 2005-08-11 | Release date: | 2006-04-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor. Acta Crystallogr.,Sect.D, 62, 2006
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3VP5
| X-ray Crystal Structure of Wild Type HrtR in the Holo Form | Descriptor: | CACODYLATE ION, PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator | Authors: | Sawai, H, Sugimoto, H, Shiro, Y, Aono, S. | Deposit date: | 2012-02-23 | Release date: | 2012-07-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis. J.Biol.Chem., 287, 2012
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3VXE
| Human alpha-thrombin-Bivalirudin complex at PD5.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BIVALIRUDIN, Thrombin heavy chain, ... | Authors: | Yamada, T, Kurihara, K, Masumi, K, Tamada, T, Tomoyori, K, Ohnishi, Y, Tanaka, I, Kuroki, R, Niimura, N. | Deposit date: | 2012-09-12 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Neutron and X-ray crystallographic analysis of the human alpha-thrombin-bivalirudin complex at pD 5.0: protonation states and hydration structure of the enzyme-product complex Biochim.Biophys.Acta, 1834, 2013
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3VGL
| Crystal structure of a ROK family glucokinase from Streptomyces griseus in complex with glucose and AMPPNP | Descriptor: | Glucokinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ... | Authors: | Miyazono, K, Tabei, N, Morita, S, Ohnishi, Y, Horinouchi, S, Tanokura, M. | Deposit date: | 2011-08-15 | Release date: | 2011-12-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Substrate recognition mechanism and substrate-dependent conformational changes of an ROK family glucokinase from Streptomyces griseus J.Bacteriol., 194, 2012
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3WV5
| Complex structure of VinN with 3-methylaspartate | Descriptor: | (2S,3S)-3-methyl-aspartic acid, Non-ribosomal peptide synthetase | Authors: | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | Deposit date: | 2014-05-15 | Release date: | 2014-10-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
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3WV4
| Crystal structure of VinN | Descriptor: | Non-ribosomal peptide synthetase | Authors: | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | Deposit date: | 2014-05-15 | Release date: | 2014-10-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
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3WVN
| Complex structure of VinN with L-aspartate | Descriptor: | ASPARTIC ACID, Non-ribosomal peptide synthetase | Authors: | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | Deposit date: | 2014-05-30 | Release date: | 2014-10-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
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3WD7
| Type III polyketide synthase | Descriptor: | COENZYME A, NICKEL (II) ION, SULFATE ION, ... | Authors: | Mori, T, Shimokawa, Y, Matsui, T, Kato, R, Sugio, S, Morita, H, Abe, I. | Deposit date: | 2013-06-10 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa To be Published
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3WD8
| TypeIII polyketide synthases | Descriptor: | GLYCEROL, Type III polyketide synthase quinolone synthase | Authors: | Mori, T, Shimokawa, Y, Matsui, T, Morita, H, Abe, I. | Deposit date: | 2013-06-10 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.463 Å) | Cite: | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa To be Published
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3WI3
| Crystal Structure of the Sld3/Treslin domain from yeast Sld3 | Descriptor: | 1,2-ETHANEDIOL, DNA replication regulator SLD3, SULFATE ION | Authors: | Itou, H, Araki, H, Shirakihara, Y. | Deposit date: | 2013-09-05 | Release date: | 2014-08-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the homology domain of the eukaryotic DNA replication proteins sld3/treslin. Structure, 22, 2014
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3WN6
| Crystal structure of alpha-amylase AmyI-1 from Oryza sativa | Descriptor: | Alpha-amylase, CALCIUM ION, D(-)-TARTARIC ACID, ... | Authors: | Ochiai, A, Sugai, H, Harada, K, Tanaka, S, Ishiyama, Y, Ito, K, Tanaka, T, Uchiumi, T, Taniguchi, M, Mitsui, T. | Deposit date: | 2013-12-05 | Release date: | 2014-09-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of alpha-amylase from Oryza sativa: molecular insights into enzyme activity and thermostability Biosci.Biotechnol.Biochem., 78, 2014
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7KZE
| Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity | Descriptor: | 1-benzyl-4-methoxybenzene, Leukotriene A-4 hydrolase, TRIETHYLENE GLYCOL, ... | Authors: | Lee, K.H, Shim, Y, Paige, M, Noble, S.M. | Deposit date: | 2020-12-10 | Release date: | 2022-06-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. Sci Rep, 12, 2022
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3X37
| Crystal structure of the N-terminal domain of Sld7 in complex with Sld3 | Descriptor: | GLYCEROL, Mitochondrial morphogenesis protein SLD7, ZYRO0C14696p | Authors: | Itou, H, Araki, H, Shirakihara, Y. | Deposit date: | 2015-01-16 | Release date: | 2015-08-19 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3. Acta Crystallogr.,Sect.D, 71, 2015
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3X38
| Crystal structure of the C-terminal domain of Sld7 | Descriptor: | GLYCEROL, Mitochondrial morphogenesis protein SLD7, SULFATE ION | Authors: | Itou, H, Araki, H, Shirakihara, Y. | Deposit date: | 2015-01-16 | Release date: | 2015-08-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3. Acta Crystallogr.,Sect.D, 71, 2015
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4AQ5
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4AQ9
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4CDO
| Crystal structure of PQBP1 bound to spliceosomal U5-15kD | Descriptor: | THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN | Authors: | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Nabeshima, Y, Okazawa, H. | Deposit date: | 2013-11-05 | Release date: | 2014-04-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
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7E18
| Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor YH-53 | Descriptor: | 1,2-ETHANEDIOL, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, Replicase polyprotein 1ab | Authors: | Senda, M, Konno, S, Hayashi, Y, Senda, T. | Deposit date: | 2021-02-01 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022
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7E19
| Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor SH-5 | Descriptor: | (phenylmethyl) N-[(2S)-1-[[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]carbamate, 3C-like proteinase | Authors: | Senda, M, Konno, S, Hayashi, Y, Senda, T. | Deposit date: | 2021-02-01 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022
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7YH6
| Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-8 Fab heavy chain, NIV-8 Fab light chain, ... | Authors: | Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. | Deposit date: | 2022-07-12 | Release date: | 2023-07-19 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants. Nat Commun, 14, 2023
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