2PLR
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![BU of 2plr by Molmil](/molmil-images/mine/2plr) | Crystal structure of dTMP kinase (st1543) from Sulfolobus Tokodaii Strain7 | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Kanaujia, S.P, Jeyakanthan, J, Rafi, Z.A, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-20 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of dTMP kinase (st1543) from Sulfolobus Tokodaii Strain7 To be Published
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2PPY
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![BU of 2ppy by Molmil](/molmil-images/mine/2ppy) | Crystal structure of Enoyl-CoA hydrates (gk_1992) from Geobacillus Kaustophilus HTA426 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Enoyl-CoA hydratase | 著者 | Kanaujia, S.P, Jeyakanthan, J, Kavyashree, M, Sekar, K, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-01 | 公開日 | 2008-05-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of Enoyl-CoA hydrates (gk_1992) from Geobacillus Kaustophilus HTA426 To be Published
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2PCJ
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![BU of 2pcj by Molmil](/molmil-images/mine/2pcj) | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 | 分子名称: | Lipoprotein-releasing system ATP-binding protein lolD, SULFITE ION | 著者 | Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 To be Published
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2PBR
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![BU of 2pbr by Molmil](/molmil-images/mine/2pbr) | Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5 | 分子名称: | SULFATE ION, Thymidylate kinase | 著者 | Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-29 | 公開日 | 2007-10-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5 To be Published
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7FFH
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![BU of 7ffh by Molmil](/molmil-images/mine/7ffh) | Diarylpentanoid-producing polyketide synthase (N199L mutant) | 分子名称: | Type III polyketide synthase | 著者 | Morita, H, Wong, C.P, Liu, Q, Takeshi, K, Lee, Y, Nakashima, Y. | 登録日 | 2021-07-23 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood. Nat Commun, 13, 2022
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2ANL
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![BU of 2anl by Molmil](/molmil-images/mine/2anl) | X-ray crystal structure of the aspartic protease plasmepsin 4 from the malarial parasite plasmodium malariae bound to an allophenylnorstatine based inhibitor | 分子名称: | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide, plasmepsin IV | 著者 | Clemente, J.C, Govindasamy, L, Madabushi, A, Fisher, S.Z, Moose, R.E, Yowell, C.A, Hidaka, K, Kimura, T, Hayashi, Y, Kiso, Y, Agbandje-McKenna, M, Dame, J.B, Dunn, B.M, McKenna, R. | 登録日 | 2005-08-11 | 公開日 | 2006-04-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor. Acta Crystallogr.,Sect.D, 62, 2006
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3VP5
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![BU of 3vp5 by Molmil](/molmil-images/mine/3vp5) | X-ray Crystal Structure of Wild Type HrtR in the Holo Form | 分子名称: | CACODYLATE ION, PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator | 著者 | Sawai, H, Sugimoto, H, Shiro, Y, Aono, S. | 登録日 | 2012-02-23 | 公開日 | 2012-07-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for the Transcriptional Regulation of Heme Homeostasis in Lactococcus lactis. J.Biol.Chem., 287, 2012
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3VXE
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![BU of 3vxe by Molmil](/molmil-images/mine/3vxe) | Human alpha-thrombin-Bivalirudin complex at PD5.0 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BIVALIRUDIN, Thrombin heavy chain, ... | 著者 | Yamada, T, Kurihara, K, Masumi, K, Tamada, T, Tomoyori, K, Ohnishi, Y, Tanaka, I, Kuroki, R, Niimura, N. | 登録日 | 2012-09-12 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Neutron and X-ray crystallographic analysis of the human alpha-thrombin-bivalirudin complex at pD 5.0: protonation states and hydration structure of the enzyme-product complex Biochim.Biophys.Acta, 1834, 2013
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3VGL
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![BU of 3vgl by Molmil](/molmil-images/mine/3vgl) | Crystal structure of a ROK family glucokinase from Streptomyces griseus in complex with glucose and AMPPNP | 分子名称: | Glucokinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ... | 著者 | Miyazono, K, Tabei, N, Morita, S, Ohnishi, Y, Horinouchi, S, Tanokura, M. | 登録日 | 2011-08-15 | 公開日 | 2011-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Substrate recognition mechanism and substrate-dependent conformational changes of an ROK family glucokinase from Streptomyces griseus J.Bacteriol., 194, 2012
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3WV5
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![BU of 3wv5 by Molmil](/molmil-images/mine/3wv5) | Complex structure of VinN with 3-methylaspartate | 分子名称: | (2S,3S)-3-methyl-aspartic acid, Non-ribosomal peptide synthetase | 著者 | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | 登録日 | 2014-05-15 | 公開日 | 2014-10-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
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3WV4
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![BU of 3wv4 by Molmil](/molmil-images/mine/3wv4) | Crystal structure of VinN | 分子名称: | Non-ribosomal peptide synthetase | 著者 | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | 登録日 | 2014-05-15 | 公開日 | 2014-10-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
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3WVN
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![BU of 3wvn by Molmil](/molmil-images/mine/3wvn) | Complex structure of VinN with L-aspartate | 分子名称: | ASPARTIC ACID, Non-ribosomal peptide synthetase | 著者 | Miyanaga, A, Cieslak, J, Shinohara, Y, Kudo, F, Eguchi, T. | 登録日 | 2014-05-30 | 公開日 | 2014-10-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of the adenylation enzyme VinN reveals a unique beta-amino acid recognition mechanism J.Biol.Chem., 289, 2014
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3WD7
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![BU of 3wd7 by Molmil](/molmil-images/mine/3wd7) | Type III polyketide synthase | 分子名称: | COENZYME A, NICKEL (II) ION, SULFATE ION, ... | 著者 | Mori, T, Shimokawa, Y, Matsui, T, Kato, R, Sugio, S, Morita, H, Abe, I. | 登録日 | 2013-06-10 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa To be Published
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3WD8
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![BU of 3wd8 by Molmil](/molmil-images/mine/3wd8) | TypeIII polyketide synthases | 分子名称: | GLYCEROL, Type III polyketide synthase quinolone synthase | 著者 | Mori, T, Shimokawa, Y, Matsui, T, Morita, H, Abe, I. | 登録日 | 2013-06-10 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.463 Å) | 主引用文献 | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa To be Published
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3WI3
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![BU of 3wi3 by Molmil](/molmil-images/mine/3wi3) | Crystal Structure of the Sld3/Treslin domain from yeast Sld3 | 分子名称: | 1,2-ETHANEDIOL, DNA replication regulator SLD3, SULFATE ION | 著者 | Itou, H, Araki, H, Shirakihara, Y. | 登録日 | 2013-09-05 | 公開日 | 2014-08-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the homology domain of the eukaryotic DNA replication proteins sld3/treslin. Structure, 22, 2014
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3WN6
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![BU of 3wn6 by Molmil](/molmil-images/mine/3wn6) | Crystal structure of alpha-amylase AmyI-1 from Oryza sativa | 分子名称: | Alpha-amylase, CALCIUM ION, D(-)-TARTARIC ACID, ... | 著者 | Ochiai, A, Sugai, H, Harada, K, Tanaka, S, Ishiyama, Y, Ito, K, Tanaka, T, Uchiumi, T, Taniguchi, M, Mitsui, T. | 登録日 | 2013-12-05 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of alpha-amylase from Oryza sativa: molecular insights into enzyme activity and thermostability Biosci.Biotechnol.Biochem., 78, 2014
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7KZE
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![BU of 7kze by Molmil](/molmil-images/mine/7kze) | Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity | 分子名称: | 1-benzyl-4-methoxybenzene, Leukotriene A-4 hydrolase, TRIETHYLENE GLYCOL, ... | 著者 | Lee, K.H, Shim, Y, Paige, M, Noble, S.M. | 登録日 | 2020-12-10 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. Sci Rep, 12, 2022
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3X37
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![BU of 3x37 by Molmil](/molmil-images/mine/3x37) | Crystal structure of the N-terminal domain of Sld7 in complex with Sld3 | 分子名称: | GLYCEROL, Mitochondrial morphogenesis protein SLD7, ZYRO0C14696p | 著者 | Itou, H, Araki, H, Shirakihara, Y. | 登録日 | 2015-01-16 | 公開日 | 2015-08-19 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3. Acta Crystallogr.,Sect.D, 71, 2015
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3X38
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![BU of 3x38 by Molmil](/molmil-images/mine/3x38) | Crystal structure of the C-terminal domain of Sld7 | 分子名称: | GLYCEROL, Mitochondrial morphogenesis protein SLD7, SULFATE ION | 著者 | Itou, H, Araki, H, Shirakihara, Y. | 登録日 | 2015-01-16 | 公開日 | 2015-08-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3. Acta Crystallogr.,Sect.D, 71, 2015
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4AQ5
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![BU of 4aq5 by Molmil](/molmil-images/mine/4aq5) | |
4AQ9
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4CDO
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![BU of 4cdo by Molmil](/molmil-images/mine/4cdo) | Crystal structure of PQBP1 bound to spliceosomal U5-15kD | 分子名称: | THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN | 著者 | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Nabeshima, Y, Okazawa, H. | 登録日 | 2013-11-05 | 公開日 | 2014-04-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
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7E18
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![BU of 7e18 by Molmil](/molmil-images/mine/7e18) | Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor YH-53 | 分子名称: | 1,2-ETHANEDIOL, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, Replicase polyprotein 1ab | 著者 | Senda, M, Konno, S, Hayashi, Y, Senda, T. | 登録日 | 2021-02-01 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022
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7E19
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![BU of 7e19 by Molmil](/molmil-images/mine/7e19) | Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor SH-5 | 分子名称: | (phenylmethyl) N-[(2S)-1-[[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]carbamate, 3C-like proteinase | 著者 | Senda, M, Konno, S, Hayashi, Y, Senda, T. | 登録日 | 2021-02-01 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022
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7YH6
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![BU of 7yh6 by Molmil](/molmil-images/mine/7yh6) | Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-8 Fab heavy chain, NIV-8 Fab light chain, ... | 著者 | Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. | 登録日 | 2022-07-12 | 公開日 | 2023-07-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants. Nat Commun, 14, 2023
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