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PDB: 1957 件

5ZV2
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FGFR-1 in complex with ligand lenvatinib
分子名称: 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide, Fibroblast growth factor receptor 1
著者Matsuki, M, Hoshi, T, Yamamoto, Y, Ikemori-Kawada, M, Minoshima, Y, Funahashi, Y, Matsui, J.
登録日2018-05-09
公開日2018-07-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models.
Cancer Med, 7, 2018
5Y5H
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SF-ROX structure of cytochrome P450nor (NO-bound state) determined at SACLA
分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ...
著者Tosha, T, Nomura, T, Nishida, T, Yamagiwa, R, Yamashita, K, Hirata, K, Ueno, G, Kimura, T, Hisano, T, Muramoto, K, Sawai, H, Takeda, H, Yamashita, A, Murakami, H, Owada, S, Tono, K, Yabashi, M, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M.
登録日2017-08-09
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
6A8U
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PhoQ sensor domain (wild type): analysis of internal cavity
分子名称: Sensor protein PhoQ
著者Yoshitani, K, Ishii, E, Taniguchi, K, Sugimoto, H, Shiro, Y, Mori, H, Akiyama, Y, Kato, A, Utsumi, R, Eguchi, Y.
登録日2018-07-10
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control.
Biosci. Biotechnol. Biochem., 83, 2019
1UG0
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Solution structure of SURP domain in BAB30904
分子名称: splicing factor 4
著者He, F, Muto, Y, Ushikoshi, R, Koshiba, S, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-06-11
公開日2004-08-03
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of SURP domain in BAB30904
To be Published
1UIL
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Double-stranded RNA-binding motif of Hypothetical protein BAB28848
分子名称: Double-stranded RNA-binding motif
著者Nagata, T, Muto, Y, Hayashi, F, Hamana, H, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-17
公開日2004-11-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of Double-stranded RNA-binding motif of Hypothetical protein BAB28848
To be Published
1IY6
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Solution structure of OMSVP3 variant, P14C/N39C
分子名称: OMSVP3
著者Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y.
登録日2002-07-23
公開日2003-03-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond
BIOCHEMISTRY, 42, 2003
1BZA
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BETA-LACTAMASE TOHO-1 FROM ESCHERICHIA COLI TUH12191
分子名称: BETA-LACTAMASE, SULFATE ION
著者Ibuka, A, Taguchi, A, Ishiguro, M, Fushinobu, S, Ishii, Y, Kamitori, S, Okuyama, K, Yamaguchi, K, Konno, M, Matsuzawa, H.
登録日1998-10-28
公開日1999-04-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution.
J.Mol.Biol., 285, 1999
1IY5
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Solution structure of wild type OMSVP3
分子名称: OMSVP3
著者Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y.
登録日2002-07-23
公開日2003-03-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond
BIOCHEMISTRY, 42, 2003
1CP8
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NMR STRUCTURE OF DNA (5'-D(TTGGCCAA)2-3') COMPLEXED WITH NOVEL ANTITUMOR DRUG UCH9
分子名称: 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE, DNA (5'-D(P*TP*TP*GP*GP*CP*CP*AP*A)-3'), MAGNESIUM ION, ...
著者Katahira, R, Katahira, M, Yamashita, Y, Ogawa, H, Kyogoku, Y, Yoshida, M.
登録日1999-06-11
公開日1999-07-01
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the novel antitumor drug UCH9 complexed with d(TTGGCCAA)2 as determined by NMR.
Nucleic Acids Res., 26, 1998
1IU1
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Crystal structure of human gamma1-adaptin ear domain
分子名称: gamma1-adaptin
著者Nogi, T, Shiba, Y, Kawasaki, M, Shiba, T, Matsugaki, N, Igarashi, N, Suzuki, M, Kato, R, Takatsu, H, Nakayama, K, Wakatsuki, S.
登録日2002-02-19
公開日2002-07-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.
Nat.Struct.Biol., 9, 2002
1SQJ
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Crystal Structure Analysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH)
分子名称: oligoxyloglucan reducing-end-specific cellobiohydrolase
著者Yaoi, K, Kondo, H, Noro, N, Suzuki, M, Tsuda, S, Mitsuishi, Y.
登録日2004-03-19
公開日2004-07-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tandem Repeat of a Seven-Bladed beta-Propeller Domain in Oligoxyloglucan Reducing-End-Specific Cellobiohydrolase
Structure, 12, 2004
3AUP
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Crystal structure of Basic 7S globulin from soybean
分子名称: Basic 7S globulin
著者Yoshizawa, T, Shimizu, T, Taichi, M, Nishiuchi, Y, Yamabe, M, Shichijo, N, Unzai, S, Hirano, H, Sato, M, Hashimoto, H.
登録日2011-02-14
公開日2011-04-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of basic 7S globulin, a xyloglucan-specific endo-beta-1,4-glucanase inhibitor protein-like protein from soybean lacking inhibitory activity against endo-beta-glucanase
Febs J., 278, 2011
7AKT
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CrPetF variant - A39G_A41V
分子名称: BENZAMIDINE, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Kurisu, G, Ohnishi, Y, Engelbrecht, V, Happe, T.
登録日2020-10-02
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Ferredoxin 2.0: an electron transfer protein designed into a photosystem I-driven hydrogenase
To Be Published
1GE9
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SOLUTION STRUCTURE OF THE RIBOSOME RECYCLING FACTOR
分子名称: RIBOSOME RECYCLING FACTOR
著者Yoshida, T, Uchiyama, S, Nakano, H, Kashimori, H, Kijima, H, Ohshima, T, Saihara, Y, Ishino, T, Shimahara, T, Yoshida, T, Yokose, K, Ohkubo, T, Kaji, A, Kobayashi, Y.
登録日2000-10-19
公開日2001-05-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the ribosome recycling factor from Aquifex aeolicus.
Biochemistry, 40, 2001
1UFN
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Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
分子名称: putative nuclear protein homolog 5830484A20Rik
著者Tochio, N, Kobayashi, N, Koshiba, S, Kigawa, T, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-06-02
公開日2004-06-22
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
To be Published
5Y5G
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Structure of cytochrome P450nor in NO-bound state: damaged by high-dose (5.7 MGy) X-ray
分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ...
著者Tosha, T, Nomura, T, Nishida, T, Ueno, G, Murakami, H, Yamashita, K, Hirata, K, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M.
登録日2017-08-09
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5F
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Structure of cytochrome P450nor in NO-bound state: damaged by low-dose (0.72 MGy) X-ray
分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ...
著者Tosha, T, Nomura, T, Nishida, T, Ueno, G, Murakami, H, Yamashita, K, Hirata, K, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M.
登録日2017-08-09
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5YZC
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Crystal structure of the prefusion form of measles virus fusion protein in complex with a fusion inhibitor compound (AS-48)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitro-2-[(phenylacetyl)amino]benzamide, ...
著者Hashiguchi, T, Fukuda, Y, Matsuoka, R, Kuroda, D, Kubota, M, Shirogane, Y, Watanabe, S, Tsumoto, K, Kohda, D, Plemper, R.K, Yanagi, Y.
登録日2017-12-14
公開日2018-02-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.334 Å)
主引用文献Structures of the prefusion form of measles virus fusion protein in complex with inhibitors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6JLG
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Crystal Structure of HasAp with Co-9,10,19,20-Tetraphenylporphycene
分子名称: GLYCEROL, Heme acquisition protein HasA, PHOSPHATE ION, ...
著者Sakakibara, E, Shisaka, Y, Onoda, H, Sugimoto, H, Shiro, Y, Watanabe, Y, Shoji, O.
登録日2019-03-05
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Highly malleable haem-binding site of the haemoprotein HasA permits stable accommodation of bulky tetraphenylporphycenes.
Rsc Adv, 9, 2019
5HWS
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Crystal structure of ketopantoate reductase from Thermococcus kodakarensis complexed with NADP+
分子名称: 2-dehydropantoate 2-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Aikawa, Y, Nishitani, Y, Miki, K.
登録日2016-01-29
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of ketopantoate reductase from Thermococcus kodakarensis complexed with NADP+
Acta Crystallogr.,Sect.F, 72, 2016
3MCH
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Crystal structure of the molybdopterin biosynthesis enzyme MoaB (TTHA0341) from thermus theromophilus HB8
分子名称: 1,2-ETHANEDIOL, Molybdopterin biosynthesis enzyme, MoaB
著者Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Baba, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2010-03-29
公開日2011-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structures, dynamics and functional implications of molybdenum-cofactor biosynthesis protein MogA from two thermophilic organisms
Acta Crystallogr.,Sect.F, 67, 2011
1J1N
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Structure Analysis of AlgQ2, A Macromolecule(Alginate)-Binding Periplasmic Protein Of Sphingomonas Sp. A1., Complexed with an Alginate Tetrasaccharide
分子名称: AlgQ2, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid
著者Momma, K, Mikami, B, Mishima, Y, Hashimoto, W, Murata, K.
登録日2002-12-11
公開日2003-06-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1, complexed with an alginate tetrasaccharide at 1.6-A resolution
J.BIOL.CHEM., 278, 2003
1IPI
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CRYSTAL STRUCTURE OF THE ARCHAEAL HOLLIDAY JUNCTION RESOLVASE HJC FROM PYROCOCCUS FURIOSUS FORM II
分子名称: HOLLIDAY JUNCTION RESOLVASE
著者Nishino, T, Komori, K, Ishino, Y, Morikawa, K.
登録日2001-05-15
公開日2001-11-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Dissection of the regional roles of the archaeal Holliday junction resolvase Hjc by structural and mutational analyses.
J.Biol.Chem., 276, 2001
4DVZ
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Crystal structure of the Helicobacter pylori CagA oncoprotein
分子名称: Cytotoxicity-associated immunodominant antigen
著者Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M.
登録日2012-02-23
公開日2012-07-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA
Cell Host Microbe, 12, 2012
4DVY
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Crystal structure of the Helicobacter pylori CagA oncoprotein
分子名称: Cytotoxicity-associated immunodominant antigen
著者Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M.
登録日2012-02-23
公開日2012-07-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA
Cell Host Microbe, 12, 2012

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