7EVN
 
 | | The cryo-EM structure of the DDX42-SF3b complex | | 分子名称: | ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2021-05-21 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
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8Y6P
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5YLZ
 | | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | | 登録日 | 2017-10-20 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017
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5Y88
 | | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... | | 著者 | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | | 登録日 | 2017-08-20 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae
Cell(Cambridge,Mass.), 171, 2017
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7EP7
 | | The complex structure of Gpsm2 and Whirlin | | 分子名称: | G-protein-signaling modulator 2, Whirlin | | 著者 | Lin, L, Shi, Y, Wang, C, Zhu, J. | | 登録日 | 2021-04-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia.
Sci Adv, 8, 2022
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5YGH
 | | Crystal Structure of the Capsid Protein from Zika Virus | | 分子名称: | Capsid protein | | 著者 | Shang, Z, Song, H, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2017-09-23 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.884 Å) | | 主引用文献 | Crystal Structure of the Capsid Protein from Zika Virus.
J. Mol. Biol., 430, 2018
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6IYC
 | | Recognition of the Amyloid Precursor Protein by Human gamma-secretase | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhou, R, Yang, G, Guo, X, Zhou, Q, Lei, J, Shi, Y. | | 登録日 | 2018-12-14 | | 公開日 | 2019-01-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Recognition of the amyloid precursor protein by human gamma-secretase.
Science, 363, 2019
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4QY0
 | | Structure of H10 from human-infecting H10N8 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | | 著者 | Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F. | | 登録日 | 2014-07-23 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
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4RDO
 | | Structure of YTH-YTHDF2 in the free state | | 分子名称: | SULFATE ION, YTH domain-containing family protein 2 | | 著者 | Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y. | | 登録日 | 2014-09-19 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
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8JOL
 | | cryo-EM structure of the CED-4/CED-3 holoenzyme | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 3, Cell death protein 4, ... | | 著者 | Li, Y, Tian, L, Zhang, Y, Shi, Y. | | 登録日 | 2023-06-07 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into CED-3 activation.
Life Sci Alliance, 6, 2023
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4RDN
 | | Structure of YTH-YTHDF2 in complex with m6A | | 分子名称: | N-methyladenosine, SULFATE ION, YTH domain-containing family protein 2 | | 著者 | Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y. | | 登録日 | 2014-09-19 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
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4QY2
 | | Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin | | 著者 | Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F. | | 登録日 | 2014-07-23 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
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6XYO
 | | Multiple system atrophy Type I alpha-synuclein filament | | 分子名称: | Alpha-synuclein | | 著者 | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2020-01-30 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
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6XYQ
 | | Multiple system atrophy Type II-2 alpha-synuclein filament | | 分子名称: | Alpha-synuclein | | 著者 | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2020-01-30 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
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6XYP
 | | Multiple system atrophy Type II-1 alpha-synuclein filament | | 分子名称: | Alpha-synuclein | | 著者 | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2020-01-30 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
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8Y6O
 | | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. | | 登録日 | 2024-02-02 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
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8X52
 | | Cryo-EM structure of human gamma-secretase in complex with Abeta49 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | | 登録日 | 2023-11-16 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
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8X54
 | | Cryo-EM structure of human gamma-secretase in complex with APP-C99 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | | 登録日 | 2023-11-16 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
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8X53
 | | Cryo-EM structure of human gamma-secretase in complex with Abeta46 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | | 登録日 | 2023-11-16 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
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4QY1
 | | Structure of H10 from human-infecting H10N8 in complex with avian receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F. | | 登録日 | 2014-07-23 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | | 主引用文献 | Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
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4R8W
 | | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ... | | 著者 | Wu, Y, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2014-09-03 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.795 Å) | | 主引用文献 | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Nat Commun, 6, 2015
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8JO0
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8JNS
 | | cryo-EM structure of a CED-4 hexamer | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 4, MAGNESIUM ION | | 著者 | Li, Y, Shi, Y. | | 登録日 | 2023-06-06 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insights into CED-3 activation.
Life Sci Alliance, 6, 2023
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4QVC
 | | E.coli Hfq in complex with RNA Aus | | 分子名称: | RNA (5'-R(*AP*U*AP*AP*CP*UP*A)-3'), RNA-binding protein Hfq | | 著者 | Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y. | | 登録日 | 2014-07-14 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
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4R12
 | | Crystal structure of the gamma-secretase component Nicastrin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Xie, T, Yan, C, Zhou, R, Zhao, Y, Sun, L, Yang, G, Lu, P, Ma, D, Shi, Y. | | 登録日 | 2014-08-03 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the gamma-secretase component nicastrin.
Proc.Natl.Acad.Sci.USA, 111, 2014
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