3WAV
| Crystal Structure of Autotaxin in Complex with Compound 10 | 分子名称: | (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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7D5V
| Structure of the C646A mutant of peptidylarginine deiminase type III (PAD3) | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein-arginine deiminase type-3 | 著者 | Akimoto, M, Mashimo, R, Unno, M. | 登録日 | 2020-09-28 | 公開日 | 2021-06-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708, 2021
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5XSZ
| Crystal structure of zebrafish lysophosphatidic acid receptor LPA6 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Lysophosphatidic acid receptor 6a,Endolysin,Lysophosphatidic acid receptor 6a | 著者 | Taniguchi, R, Nishizawa, T, Ishitani, R, Nureki, O. | 登録日 | 2017-06-16 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 Nature, 548, 2017
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3VQX
| Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in triclinic crystal form | 分子名称: | ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Pyrrolysine--tRNA ligase, ... | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2012-04-02 | 公開日 | 2013-01-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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3VVP
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3VQW
| Crystal structure of the SeMet substituted catalytic domain of pyrrolysyl-tRNA synthetase | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2012-04-01 | 公開日 | 2013-01-02 | 最終更新日 | 2013-09-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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3VQY
| Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and AMPPNP (form 2) | 分子名称: | MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2012-04-02 | 公開日 | 2013-01-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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3VVR
| Crystal structure of MATE in complex with MaD5 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative uncharacterized protein, macrocyclic peptide | 著者 | Tanaka, Y, Ishitani, R, Nureki, O. | 登録日 | 2012-07-27 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3VWA
| Crystal structure of Cex1p | 分子名称: | Cytoplasmic export protein 1 | 著者 | Nozawa, K, Ishitani, R, Nureki, O. | 登録日 | 2012-08-13 | 公開日 | 2013-06-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm Nucleic Acids Res., 41, 2013
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3VVS
| Crystal structure of MATE in complex with MaD3S | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative uncharacterized protein, macrocyclic peptide | 著者 | Tanaka, Y, Ishitani, R, Nureki, O. | 登録日 | 2012-07-27 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3VVO
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3VVN
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3WO7
| Crystal structure of YidC from Bacillus halodurans (form II) | 分子名称: | COPPER (II) ION, Membrane protein insertase YidC 2 | 著者 | Kumazaki, K, Tsukazaki, T, Ishitani, R, Nureki, O. | 登録日 | 2013-12-20 | 公開日 | 2014-04-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | Structural basis of Sec-independent membrane protein insertion by YidC. Nature, 509, 2014
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3WBN
| Crystal structure of MATE in complex with MaL6 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MaL6, Putative uncharacterized protein | 著者 | Tanaka, Y, Ishitani, R, Nureki, O. | 登録日 | 2013-05-20 | 公開日 | 2013-06-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3WO6
| Crystal structure of YidC from Bacillus halodurans (form I) | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CADMIUM ION, Membrane protein insertase YidC 2 | 著者 | Kumazaki, K, Tsukazaki, T, Ishitani, R, Nureki, O. | 登録日 | 2013-12-20 | 公開日 | 2014-04-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Structural basis of Sec-independent membrane protein insertion by YidC. Nature, 509, 2014
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3W4T
| Crystal structure of MATE P26A mutant | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative uncharacterized protein | 著者 | Tanaka, Y, Ishitani, R, Nureki, O. | 登録日 | 2013-01-16 | 公開日 | 2013-04-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.096 Å) | 主引用文献 | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3UG9
| Crystal Structure of the Closed State of Channelrhodopsin | 分子名称: | Archaeal-type opsin 1, Archaeal-type opsin 2, OLEIC ACID, ... | 著者 | Kato, H.E, Ishitani, R, Nureki, O. | 登録日 | 2011-11-02 | 公開日 | 2012-01-25 | 最終更新日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the channelrhodopsin light-gated cation channel Nature, 482, 2012
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3W9H
| Structural basis for the inhibition of bacterial multidrug exporters | 分子名称: | Acriflavine resistance protein B, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | 著者 | Sakurai, K, Nagata, C, Nakashima, R, Yamaguchi, A. | 登録日 | 2013-04-04 | 公開日 | 2013-07-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters Nature, 500, 2013
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3WQH
| Crystal Structure of human DPP-IV in complex with Anagliptin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide | 著者 | Watanabe, Y.S, Okada, S, Motoyama, T, Takahashi, R, Adachi, H, Oka, M. | 登録日 | 2014-01-27 | 公開日 | 2015-07-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Anagliptin, a potent dipeptidyl peptidase IV inhibitor: its single-crystal structure and enzyme interactions. J Enzyme Inhib Med Chem, 30, 2015
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2ZBZ
| Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D3 | 分子名称: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | 登録日 | 2007-10-30 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
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2ZBY
| Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) | 分子名称: | Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | 登録日 | 2007-10-30 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
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5ZSU
| Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms | 分子名称: | Volume-regulated anion channel subunit LRRC8A | 著者 | Kasuya, G, Nakane, T, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | 登録日 | 2018-04-29 | 公開日 | 2018-08-15 | 最終更新日 | 2018-09-26 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Cryo-EM structures of the human volume-regulated anion channel LRRC8. Nat. Struct. Mol. Biol., 25, 2018
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2ZBX
| Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (wild type) with imidazole bound | 分子名称: | Cytochrome P450-SU1, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | 登録日 | 2007-10-30 | 公開日 | 2008-04-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
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2YWH
| Crystal structure of GDP-bound LepA from Aquifex aeolicus | 分子名称: | GTP-binding protein LepA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Kawazoe, M, Takemoto, C, Kaminishi, T, Nishino, A, Nakayama-Ushikoshi, R, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-20 | 公開日 | 2008-04-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal structures of GTP-binding protein LepA from Aquifex aeolicus. To be Published
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2YWF
| Crystal structure of GMPPNP-bound LepA from Aquifex aeolicus | 分子名称: | GTP-binding protein lepA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Kawazoe, M, Takemoto, C, Kaminishi, T, Nishino, A, Nakayama-Ushikoshi, R, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-20 | 公開日 | 2008-04-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal structures of GTP-binding protein LepA from Aquifex aeolicus To be Published
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