3VVS

Crystal structure of MATE in complex with MaD3S

Summary for 3VVS

• Entry DOI: 10.2210/pdb3vvs/pdb
• Related: 3VVN 3VVO 3VVP 3VVQ 3VVR
• Descriptor: Putative uncharacterized protein, macrocyclic peptide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total)
• Functional Keywords: mate, multidrug transporter, macrocyclic peptide, transport protein, transport protein-inhibitor complex, transport protein/inhibitor
• Biological source: Pyrococcus furiosus; More
• Total number of polymer chains: 2
• Total formula weight: 54744.16

Authors

Tanaka, Y.,Ishitani, R.,Nureki, O. (deposition date: 2012-07-27, release date: 2013-04-03, Last modification date: 2023-11-08)

• Primary citation: Tanaka, Y.,Hipolito, C.J.,Maturana, A.D.,Ito, K.,Kuroda, T.,Higuchi, T.,Katoh, T.,Kato, H.E.,Hattori, M.,Kumazaki, K.,Tsukazaki, T.,Ishitani, R.,Suga, H.,Nureki, O.; Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.; Nature, 496:247-251, 2013; PubMed: 23535598; DOI: 10.1038/nature12014

Experimental method

X-RAY DIFFRACTION (2.6 Å)