3WAW
| Crystal Structure of Autotaxin in Complex with 2BoA | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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5T00
| Human CTCF ZnF3-7 and methylated DNA complex | 分子名称: | DNA (5'-GCCAGCAGGGGG(5CM)GCTA-3'), DNA (5'-TAG(5CM)GCCCCCTGCTGGC-3'), Transcriptional repressor CTCF, ... | 著者 | Hashimoto, H, Wang, D, Cheng, X. | 登録日 | 2016-08-15 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
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8JF5
| Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAS1440 | 分子名称: | 4-[5-[(3~{R})-3-azanylpyrrolidin-1-yl]carbonyl-2-[2-fluoranyl-4-(2-methyl-2-oxidanyl-propyl)phenyl]phenyl]-2-fluoranyl-benzenecarbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Fukushima, H, Machida, T, Yamashita, S, Suzuki, T. | 登録日 | 2023-05-17 | 公開日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | TAS1440, a histone H3 competitive LSD1 inhibitor, activates both TGF-beta and notch signaling pathways via INSM1 dissociation in neuroendocrine small cell lung cancer To Be Published
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5ZFS
| Crystal structure of Arthrobacter globiformis M30 sugar epimerase which can produce D-allulose from D-fructose | 分子名称: | ACETATE ION, D-allulose-3-epimerase, MANGANESE (II) ION | 著者 | Yoshida, H, Yoshihara, A, Gullapalli, P.K, Ohtani, K, Akimitsu, K, Izumori, K, Kamitori, S. | 登録日 | 2018-03-07 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D-allulose from D-fructose. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5T0U
| CTCF ZnF2-7 and DNA complex structure | 分子名称: | DNA (5'-D(*CP*CP*TP*CP*AP*CP*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*AP*GP*TP*GP*AP*GP*G)-3'), Transcriptional repressor CTCF, ... | 著者 | Hashimoto, H, Wang, D, Cheng, X. | 登録日 | 2016-08-16 | 公開日 | 2017-05-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.199 Å) | 主引用文献 | Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
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3WAX
| Crystal Structure of Autotaxin in Complex with 3BoA | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAY
| Crystal Structure of Autotaxin in Complex with 4BoA | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.746 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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3WAV
| Crystal Structure of Autotaxin in Complex with Compound 10 | 分子名称: | (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
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1J1T
| Alginate lyase from Alteromonas sp.272 | 分子名称: | Alginate Lyase, CALCIUM ION, SULFATE ION | 著者 | Motoshima, H, Iwatomo, Y, Watanabe, K, Oda, T, Muramatsu, T. | 登録日 | 2002-12-14 | 公開日 | 2004-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Alginate Lyase from Alteromonas sp.272 To be published
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3VUX
| Crystal structure of A20 ZF7 in complex with linear ubiquitin, form II | 分子名称: | 1,2-ETHANEDIOL, POTASSIUM ION, Polyubiquitin-C, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2012-07-09 | 公開日 | 2013-02-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | 主引用文献 | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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3WXR
| Yeast 20S proteasome with a mutation of alpha7 subunit | 分子名称: | Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | 著者 | Yashiroda, H, Toda, Y, Otsu, S, Takagi, K, Mizushima, T, Murata, S. | 登録日 | 2014-08-06 | 公開日 | 2014-10-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | N-terminal alpha 7 deletion of the proteasome 20S core particle substitutes for yeast PI31 function Mol.Cell.Biol., 35, 2015
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5XG3
| Crystal structure of the ATPgS-engaged Smc head domain with an extended coiled coil bound to the C-terminal domain of ScpA derived from Bacillus subtilis | 分子名称: | COBALT (II) ION, Chromosome partition protein Smc, MAGNESIUM ION, ... | 著者 | Shin, H.-C, Lee, H, Oh, B.-H. | 登録日 | 2017-04-11 | 公開日 | 2017-06-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization Mol. Cell, 67, 2017
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3VUY
| Crystal structure of A20 ZF7 in complex with linear tetraubiquitin | 分子名称: | POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2012-07-09 | 公開日 | 2013-02-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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3VYV
| Crystal structure of subtilisin NAT at 1.36 | 分子名称: | CALCIUM ION, GLYCEROL, Subtilisin NAT | 著者 | Ushijima, H, Fuchita, N, Kajiwara, T, Motoshima, H, Ueno, G, Watanabe, K. | 登録日 | 2012-10-03 | 公開日 | 2013-10-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Crystal structure of subtilisin NAT at 1.36 TO BE PUBLISHED
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3VUW
| Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I | 分子名称: | POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2012-07-09 | 公開日 | 2013-02-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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2MQE
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5XAW
| Parallel homodimer structures of voltage-gated sodium channel beta4 for cell-cell adhesion | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, Sodium channel subunit beta-4, ... | 著者 | Shimizu, H, Yokoyama, S. | 登録日 | 2017-03-15 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta 4 subunit explain its role in cell-cell adhesion J. Biol. Chem., 292, 2017
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1UF8
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine | 分子名称: | D-[(AMINO)CARBONYL]PHENYLALANINE, N-carbamyl-D-amino acid amidohydrolase | 著者 | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | 登録日 | 2003-05-26 | 公開日 | 2004-06-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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5YD8
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3W2T
| Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with vildagliptin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(1r,3s,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]decan-1-yl]amino}-1-{(2S)-2-[(E)-iminomethyl]pyrrolidin-1-yl}ethan-1-o ne, ... | 著者 | Kishida, H, Nabeno, M, Miyaguchi, I, Tanaka, Y, Katou, R, Akahoshi, F. | 登録日 | 2012-12-04 | 公開日 | 2013-05-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site Biochem.Biophys.Res.Commun., 434, 2013
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1UF4
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase | 分子名称: | N-carbamyl-D-amino acid amidohydrolase | 著者 | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | 登録日 | 2003-05-23 | 公開日 | 2004-06-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid To be published
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5XGC
| Crystal structure of SmgGDS-558 | 分子名称: | Rap1 GTPase-GDP dissociation stimulator 1 | 著者 | Shimizu, H, Toma-Fukai, S, Shimizu, T. | 登録日 | 2017-04-13 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding J. Biol. Chem., 292, 2017
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1UF7
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-valine | 分子名称: | 3-METHYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | 著者 | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | 登録日 | 2003-05-26 | 公開日 | 2004-06-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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1UF5
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine | 分子名称: | 1,2-ETHANEDIOL, 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | 著者 | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | 登録日 | 2003-05-23 | 公開日 | 2004-06-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of C171A/V236A mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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1V6R
| Solution Structure of Endothelin-1 with its C-terminal Folding | 分子名称: | Endothelin-1 | 著者 | Takashima, H, Mimura, N, Ohkubo, T, Yoshida, T, Tamaoki, H, Kobayashi, Y. | 登録日 | 2003-12-03 | 公開日 | 2004-03-16 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Distributed Computing and NMR Constraint-Based High-Resolution Structure
Determination: Applied for Bioactive Peptide Endothelin-1 To Determine C-Terminal
Folding J.Am.Chem.Soc., 126, 2004
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