5ZFS
 
 | | Crystal structure of Arthrobacter globiformis M30 sugar epimerase which can produce D-allulose from D-fructose | | 分子名称: | ACETATE ION, D-allulose-3-epimerase, MANGANESE (II) ION | | 著者 | Yoshida, H, Yoshihara, A, Gullapalli, P.K, Ohtani, K, Akimitsu, K, Izumori, K, Kamitori, S. | | 登録日 | 2018-03-07 | | 公開日 | 2018-10-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D-allulose from D-fructose.
Acta Crystallogr F Struct Biol Commun, 74, 2018
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7VBV
 | | Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 7 | | 分子名称: | ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Orita, T, Doi, S, Iwanaga, T, Fujishima, A, Adachi, T. | | 登録日 | 2021-09-01 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors.
Bioorg.Med.Chem., 52, 2021
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5OLA
 | | Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM | | 分子名称: | DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ... | | 著者 | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | | 登録日 | 2017-07-27 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.904 Å) | | 主引用文献 | Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
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5OL9
 | | Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain | | 分子名称: | ACETATE ION, Transcription elongation factor, mitochondrial | | 著者 | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | | 登録日 | 2017-07-27 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | | 主引用文献 | Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
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5ODW
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7WT1
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5XOY
 | | Crystal structure of LysK from Thermus thermophilus in complex with Lysine | | 分子名称: | LYSINE, SULFATE ION, [LysW]-lysine hydrolase | | 著者 | Tomita, T, Fujita, S, Hasebe, F, Cho, S.-H, Yoshida, A, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2017-05-31 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW
Biochem. Biophys. Res. Commun., 491, 2017
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7VBX
 | | Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 20 | | 分子名称: | (3~{S})-3-[5-(8-cyclopropyl-2-methyl-9~{H}-pyrido[2,3-b]indol-3-yl)-1,3,4-oxadiazol-2-yl]-4-methyl-~{N}-[(1~{R})-1-phenylethyl]pentanamide, ACETATE ION, CHLORIDE ION, ... | | 著者 | Orita, T, Doi, S, Iwanaga, T, Fujishima, A, Adachi, T. | | 登録日 | 2021-09-01 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors.
Bioorg.Med.Chem., 52, 2021
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2D1X
 | | The crystal structure of the cortactin-SH3 domain and AMAP1-peptide complex | | 分子名称: | SULFATE ION, cortactin isoform a, proline rich region from development and differentiation enhancing factor 1 | | 著者 | Hashimoto, S, Hirose, M, Hashimoto, A, Morishige, M, Yamada, A, Hosaka, H, Akagi, K, Ogawa, E, Oneyama, C, Agatsuma, T, Okada, M, Kobayashi, H, Wada, H, Nakano, H, Ikegami, T, Nakagawa, A, Sabe, H. | | 登録日 | 2005-09-01 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1X2R
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, Nuclear factor erythroid 2 related factor 2, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-26 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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2NCY
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2CZL
 | | Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8 (Cys11 modified with beta-mercaptoethanol) | | 分子名称: | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, L(+)-TARTARIC ACID, POTASSIUM ION, ... | | 著者 | Arai, R, Nishino, A, Nagano, K, Kamo-Uchikubo, T, Nishimoto, M, Toyama, M, Terada, T, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-13 | | 公開日 | 2006-01-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8.
J.Struct.Biol., 168, 2009
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2E0I
 | | Crystal structure of archaeal photolyase from Sulfolobus tokodaii with two FAD molecules: Implication of a novel light-harvesting cofactor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 432aa long hypothetical deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Fujihashi, M, Numoto, N, Kobayashi, Y, Mizushima, A, Tsujimura, M, Nakamura, A, Kawarabayashi, Y, Miki, K. | | 登録日 | 2006-10-10 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Archaeal Photolyase from Sulfolobus tokodaii with Two FAD Molecules: Implication of a Novel Light-harvesting Cofactor
J.Mol.Biol., 365, 2007
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2NCX
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5X6Y
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1X2J
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-25 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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2DUK
 | | Crystal structure of MS0616 | | 分子名称: | MS0616 | | 著者 | Hosaka, T, Nishino, A, Uchikubo, K.-T, Kishishita, S, Murayama, K, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-07-24 | | 公開日 | 2007-01-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Crystal structure of MS0616
To be Published
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5ZFG
 | | Crystal structure of a diazinon-metabolizing glutathione S-transferase in the silkworm, Bombyx mori | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Glutathione S-transferase | | 著者 | Yamamoto, K, Higashiura, A, Nakagawa, A. | | 登録日 | 2018-03-06 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Characterisation of a diazinon-metabolising glutathione S-transferase in the silkworm Bombyx mori by X-ray crystallography and genome editing analysis.
Sci Rep, 8, 2018
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5ZF1
 | | Molecular structure of a novel 5,10-methylenetetrahydrofolate dehydrogenase from the silkworm, Bombyx mori | | 分子名称: | 1,2-ETHANEDIOL, 5,10-methylenetetrahydrofolate dehydrogenase, SULFATE ION | | 著者 | Haque, R, Higashiura, A, Nakagawa, A, Yamamoto, K. | | 登録日 | 2018-03-02 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular structure of a 5,10-methylenetetrahydrofolate dehydrogenase from the silkwormBombyx mori.
FEBS Open Bio, 9, 2019
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2CWN
 | | Crystal structure of mouse transaldolase | | 分子名称: | Transaldolase | | 著者 | Handa, N, Arai, R, Nishino, A, Uchikubo, T, Takemoto, C, Morita, S, Kinoshita, Y, Nagano, Y, Uda, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-06-22 | | 公開日 | 2005-12-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of mouse transaldolase
To be Published
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5X6Z
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1UG9
 | | Crystal Structure of Glucodextranase from Arthrobacter globiformis I42 | | 分子名称: | CALCIUM ION, GLYCEROL, glucodextranase | | 著者 | Mizuno, M, Tonozuka, T, Suzuki, S, Uotsu-Tomita, R, Ohtaki, A, Kamitori, S, Nishikawa, A, Sakano, Y. | | 登録日 | 2003-06-16 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into substrate specificity and function of glucodextranase
J.Biol.Chem., 279, 2004
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5Y9T
 | | Crystal Structure of EGFR T790M mutant in complex with naquotinib | | 分子名称: | 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-2-carboxamide, Epidermal growth factor receptor | | 著者 | Mimasu, S, Tomimoto, Y, Maiko, I, Yasushi, A, Tatsuya, N. | | 登録日 | 2017-08-28 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, inEGFR-Mutated Non-Small Cell Lung Cancer.
Mol. Cancer Ther., 17, 2018
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2ZJU
 | | Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein (Ls-AChBP) Complexed with Imidacloprid | | 分子名称: | (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, Acetylcholine-binding protein | | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Morimoto, T, Matsuda, K. | | 登録日 | 2008-03-10 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin
Invert.Neurosci., 8, 2008
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1VB9
 | | Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) complexed with transglycosylated product | | 分子名称: | CALCIUM ION, alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-[alpha-D-glucopyranose-(1-6)]alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-amylase II | | 著者 | Mizuno, M, Tonozuka, T, Uechi, A, Ohtaki, A, Ichikawa, K, Kamitori, S, Nishikawa, A, Sakano, Y. | | 登録日 | 2004-02-25 | | 公開日 | 2005-03-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) complexed with transglycosylated product
EUR.J.BIOCHEM., 271, 2004
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