7WT1
human glyoxalase I (with C-ter His tag) in inhibitor-free form
Summary for 7WT1
Entry DOI | 10.2210/pdb7wt1/pdb |
Descriptor | Lactoylglutathione lyase, ZINC ION (3 entities in total) |
Functional Keywords | glyoxalase i, zinc metalloenzyme, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 43880.56 |
Authors | Usami, M.,Shibuya, A.,Yokoyama, H. (deposition date: 2022-02-03, release date: 2022-04-13, Last modification date: 2023-11-29) |
Primary citation | Usami, M.,Ando, K.,Shibuya, A.,Takasawa, R.,Yokoyama, H. Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference. Febs Lett., 596:1458-1467, 2022 Cited by PubMed: 35363883DOI: 10.1002/1873-3468.14344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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