7WT1

human glyoxalase I (with C-ter His tag) in inhibitor-free form

Summary for 7WT1

Entry DOI	10.2210/pdb7wt1/pdb
Descriptor	Lactoylglutathione lyase, ZINC ION (3 entities in total)
Functional Keywords	glyoxalase i, zinc metalloenzyme, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	43880.56
Authors	Usami, M.,Shibuya, A.,Yokoyama, H. (deposition date: 2022-02-03, release date: 2022-04-13, Last modification date: 2023-11-29)
Primary citation	Usami, M.,Ando, K.,Shibuya, A.,Takasawa, R.,Yokoyama, H. Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference. Febs Lett., 596:1458-1467, 2022 Cited by PubMed: 35363883 DOI: 10.1002/1873-3468.14344 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation