1MQ1
 
 | | Ca2+-S100B-TRTK-12 complex | | Descriptor: | F-actin capping protein alpha-1 subunit, S-100 protein, beta chain | | Authors: | McClintock, K.A, Shaw, G.S. | | Deposit date: | 2002-09-13 | | Release date: | 2002-12-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A novel S100 target conformation is revealed by the solution structure of the Ca2+-S100B-TRTK-12 complex.
J.Biol.Chem., 278, 2003
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1YYM
 | | crystal structure of F23, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), ... | | Authors: | Huang, C.C, Stricher, F, Martin, L, Decker, J.M, Majeed, S, Barthe, P, Hendrickson, W.A, Robinson, J, Roumestand, C, Sodroski, J, Wyatt, R, Shaw, G.M, Vita, C, Kwong, P.D. | | Deposit date: | 2005-02-25 | | Release date: | 2005-05-03 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Structure, 13, 2005
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2JMO
 | | IBR domain of Human Parkin | | Descriptor: | Parkin, ZINC ION | | Authors: | Beasley, S.A, Hristova, V.A, Shaw, G.S. | | Deposit date: | 2006-11-24 | | Release date: | 2007-02-27 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease.
Proc.Natl.Acad.Sci.USA, 104, 2007
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4DRW
 | | Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide | | Descriptor: | Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein | | Authors: | Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S. | | Deposit date: | 2012-02-17 | | Release date: | 2012-10-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of an asymmetric ternary protein complex provides insight for membrane interaction.
Structure, 20, 2012
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4M2Z
 | | Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE) | | Descriptor: | CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA10, ... | | Authors: | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | | Deposit date: | 2013-08-05 | | Release date: | 2013-12-11 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | RNase III: Genetics and Function; Structure and Mechanism.
Annu. Rev. Genet., 47, 2013
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8T0S
 | | Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position | | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2 | | Authors: | Wang, C, Shaw, G.X, Shi, G, Ji, X. | | Deposit date: | 2023-06-01 | | Release date: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position
To be published
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4M30
 | | Crystal structure of RNASE III complexed with double-stranded RNA AND AMP (TYPE II CLEAVAGE) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | | Deposit date: | 2013-08-05 | | Release date: | 2013-12-11 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | RNase III: Genetics and Function; Structure and Mechanism.
Annu. Rev. Genet., 47, 2013
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1FXT
 | | STRUCTURE OF A CONJUGATING ENZYME-UBIQUITIN THIOLESTER COMPLEX | | Descriptor: | UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2-24 KDA | | Authors: | Hamilton, K.S, Shaw, G.S, Williams, R.S, Huzil, J.T, McKenna, S, Ptak, C, Glover, M, Ellison, M.J. | | Deposit date: | 2000-09-26 | | Release date: | 2001-10-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.
Structure, 9, 2001
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1HMA
 | | THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER | | Descriptor: | HMG-D | | Authors: | Jones, D.N.M, Searles, M.A, Shaw, G.L, Churchill, M.E.A, Ner, S.S, Keeler, J, Travers, A.A, Neuhaus, D. | | Deposit date: | 1994-05-12 | | Release date: | 1994-07-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster.
Structure, 2, 1994
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2NUF
 | | Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.5-Angstrom Resolution | | Descriptor: | 28-MER, MAGNESIUM ION, Ribonuclease III | | Authors: | Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X. | | Deposit date: | 2006-11-09 | | Release date: | 2007-11-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
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2NUG
 | | Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 1.7-Angstrom Resolution | | Descriptor: | 5'-R(P*AP*AP*GP*GP*UP*CP*AP*UP*UP*CP*G)-3', 5'-R(P*AP*GP*UP*GP*GP*CP*CP*UP*UP*GP*C)-3', MAGNESIUM ION, ... | | Authors: | Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X. | | Deposit date: | 2006-11-09 | | Release date: | 2007-11-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
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2PRU
 | | NMR Structure of Human apoS100B at 10C | | Descriptor: | Protein S100-B | | Authors: | Malik, S, Shaw, G.S, Revington, M. | | Deposit date: | 2007-05-04 | | Release date: | 2008-04-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Analysis of the structure of human apo-S100B at low temperature indicates a unimodal conformational distribution is adopted by calcium-free S100 proteins.
Proteins, 73, 2008
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1F6V
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2NUE
 | | Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.9-Angstrom Resolution | | Descriptor: | 46-MER, Ribonuclease III | | Authors: | Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X. | | Deposit date: | 2006-11-09 | | Release date: | 2007-11-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
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2PCX
 | | Crystal structure of p53DBD(R282Q) at 1.54-angstrom Resolution | | Descriptor: | Cellular tumor antigen p53, ZINC ION | | Authors: | Tu, C, Shaw, G, Ji, X. | | Deposit date: | 2007-03-30 | | Release date: | 2008-04-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Impact of low-frequency hotspot mutation R282Q on the structure of p53 DNA-binding domain as revealed by crystallography at 1.54 angstroms resolution.
Acta Crystallogr.,Sect.D, 64, 2008
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5TR5
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2LGY
 | | Ubiquitin-like domain from HOIL-1 | | Descriptor: | RanBP-type and C3HC4-type zinc finger-containing protein 1 | | Authors: | Beasley, S.A, Shaw, G.S. | | Deposit date: | 2011-08-03 | | Release date: | 2012-06-20 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the E3 ligase HOIL-1 Ubl domain.
Protein Sci., 21, 2012
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2LGV
 | | Rbx1 | | Descriptor: | E3 ubiquitin-protein ligase RBX1, ZINC ION | | Authors: | Spratt, D.E, Shaw, G.S. | | Deposit date: | 2011-08-02 | | Release date: | 2012-03-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase.
J.Biol.Chem., 287, 2012
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2M48
 | | Solution Structure of IBR-RING2 Tandem Domain from Parkin | | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION | | Authors: | Noh, Y.J, Mercier, P, Spratt, D.E, Shaw, G.S. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
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2LWR
 | | Solution Structure of RING2 Domain from Parkin | | Descriptor: | SD01679p, ZINC ION | | Authors: | Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S. | | Deposit date: | 2012-08-06 | | Release date: | 2013-06-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
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2M9Y
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7JOF
 | | Calcium-bound C2A Domain from Human Dysferlin | | Descriptor: | CALCIUM ION, Isoform 6 of Dysferlin | | Authors: | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | | Deposit date: | 2020-08-06 | | Release date: | 2021-06-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Biochem.J., 478, 2021
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7K6B
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7KRB
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4UU9
 | | Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody | | Descriptor: | COMPLEMENT C5, MEDI7814, SULFATE ION | | Authors: | Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T. | | Deposit date: | 2014-07-25 | | Release date: | 2015-08-12 | | Last modified: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
MAbs, 10, 2018
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