7A3Q
| Crystal structure of dengue 4 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10 | Descriptor: | (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | Deposit date: | 2020-08-18 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184, 2021
|
|
5ITZ
| |
3UL3
| |
7PJF
| Inhibiting parasite proliferation using a rationally designed anti-tubulin agent | Descriptor: | Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Sharma, A, Gaillard, N, Ehrhard, V.A, Steinmetz, M.O. | Deposit date: | 2021-08-24 | Release date: | 2021-09-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.862 Å) | Cite: | Inhibiting parasite proliferation using a rationally designed anti-tubulin agent. Embo Mol Med, 13, 2021
|
|
7PJE
| Inhibiting parasite proliferation using a rationally designed anti-tubulin agent | Descriptor: | Darpin D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Sharma, A, Gaillard, N, Ehrhard, V.A, Steinmetz, M.O. | Deposit date: | 2021-08-24 | Release date: | 2021-09-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Inhibiting parasite proliferation using a rationally designed anti-tubulin agent. Embo Mol Med, 13, 2021
|
|
1FNH
| CRYSTAL STRUCTURE OF HEPARIN AND INTEGRIN BINDING SEGMENT OF HUMAN FIBRONECTIN | Descriptor: | PROTEIN (FIBRONECTIN) | Authors: | Sharma, A, Askari, J, Humphries, M, Jones, E.Y, Stuart, D.I. | Deposit date: | 1999-01-28 | Release date: | 1999-03-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a heparin- and integrin-binding segment of human fibronectin. EMBO J., 18, 1999
|
|
3STK
| |
2W8B
| Crystal structure of processed TolB in complex with Pal | Descriptor: | ACETATE ION, GLYCEROL, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, ... | Authors: | Sharma, A, Bonsor, D.A, Kleanthous, C. | Deposit date: | 2009-01-15 | Release date: | 2009-02-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins. Embo J., 28, 2009
|
|
3STN
| Structure of human LFABP (apo-LFABP) | Descriptor: | Fatty acid-binding protein, liver | Authors: | Sharma, A, Sharma, A. | Deposit date: | 2011-07-11 | Release date: | 2011-08-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.595 Å) | Cite: | Fatty acid induced remodeling within the Human liver fatty acid binding protein J.Biol.Chem., 2011
|
|
3STM
| |
6FLK
| |
6FLJ
| |
1VCC
| |
5M7J
| Blastochloris viridis photosynthetic reaction center structure using best crystal approach | Descriptor: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL A, ... | Authors: | Sharma, A.S, Johansson, L, Dunevall, E, Wahlgren, W.Y, Neutze, R, Katona, G. | Deposit date: | 2016-10-28 | Release date: | 2017-02-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Asymmetry in serial femtosecond crystallography data. Acta Crystallogr A Found Adv, 73, 2017
|
|
5M7K
| Blastochloris viridis photosynthetic reaction center - RC_vir_xfel | Descriptor: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL A, ... | Authors: | Sharma, A.S, Johansson, L, Dunevall, E, Wahlgren, W.Y, Neutze, R, Katona, G. | Deposit date: | 2016-10-28 | Release date: | 2017-02-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Asymmetry in serial femtosecond crystallography data. Acta Crystallogr A Found Adv, 73, 2017
|
|
5M7L
| Blastochloris viridis photosynthetic reaction center synchrotron structure | Descriptor: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL A, ... | Authors: | Sharma, A.S, Johansson, L, Dunevall, E, Wahlgren, W.Y, Neutze, R, Katona, G. | Deposit date: | 2016-10-28 | Release date: | 2017-02-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Asymmetry in serial femtosecond crystallography data. Acta Crystallogr A Found Adv, 73, 2017
|
|
4PG3
| Crystal structure of KRS complexed with inhibitor | Descriptor: | LYSINE, Lysine--tRNA ligase, cladosporin | Authors: | Sharma, A, Yogavel, M, Khan, S, Sharma, A, Belrhali, H. | Deposit date: | 2014-05-01 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin. J. Struct. Funct. Genomics, 15, 2014
|
|
2K84
| Solution Structure of the equine infectious anemia virus p9 GAG protein | Descriptor: | P9 | Authors: | Sharma, A, Bruns, K, Roeder, R, Henklein, P, Votteler, J, Wray, V, Sharma, U. | Deposit date: | 2008-09-02 | Release date: | 2009-09-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Equine Infectious Anemia Virus p9 protein: a rationalization of its different ALIX binding requirements compared to the analogous HIV-p6 protein Bmc Struct.Biol., 9, 2009
|
|
4HR6
| Crystal structure of snake gourd (Trichosanthes anguina) seed lectin, a three chain homologue of type II RIPs | Descriptor: | LECTIN, methyl alpha-D-galactopyranoside | Authors: | Sharma, A, Pohlentz, G, Bobbili, K.B, Jeyaprakash, A.A, Chandran, T, Mormann, M, Swamy, M.J, Vijayan, M. | Deposit date: | 2012-10-26 | Release date: | 2013-08-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The sequence and structure of snake gourd (Trichosanthes anguina) seed lectin, a three-chain nontoxic homologue of type II RIPs. Acta Crystallogr.,Sect.D, 69, 2013
|
|
4IR1
| Polymerase-DNA Complex | Descriptor: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Sharma, A, Nair, D.T. | Deposit date: | 2013-01-14 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
|
|
4IR9
| Polymerase-DNA complex | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(P*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Sharma, A, Nair, D.T. | Deposit date: | 2013-01-14 | Release date: | 2013-04-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
|
|
3TED
| Crystal structure of the Chd1 DNA-binding domain in complex with a DNA duplex | Descriptor: | 5'-D(*CP*CP*AP*TP*AP*TP*AP*TP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*AP*TP*AP*TP*AP*TP*GP*G)-3', Chromo domain-containing protein 1 | Authors: | Sharma, A, Jenkins, K.R, Heroux, A, Bowman, G.D. | Deposit date: | 2011-08-12 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | DNA-binding domain of Chd1 in complex with a DNA duplex J.Biol.Chem., 2011
|
|
6S8K
| Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes | Descriptor: | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Sharma, A, Olieric, N, Steinmetz, M. | Deposit date: | 2019-07-10 | Release date: | 2019-11-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes Chem, 5, 2019
|
|
5NR4
| Crystal structure of Clasp2 TOG1 domain | Descriptor: | CLIP-associating protein 2 | Authors: | Sharma, A, Olieric, N, Weinert, T, Olieric, V, Steinmetz, M.O. | Deposit date: | 2017-04-21 | Release date: | 2018-05-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.198 Å) | Cite: | CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain. Dev. Cell, 46, 2018
|
|
5NJH
| Triazolopyrimidines stabilize microtubules by binding to the vinca inhibitor site of tubulin | Descriptor: | 5-chloranyl-7-[(1~{R},5~{S})-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl]-6-[2,4,6-tris(fluoranyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sharma, A, Calvo, G.S, Prota, A.E, Diaz, J.F, Steinmetz, M.O. | Deposit date: | 2017-03-28 | Release date: | 2017-06-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin. Cell Chem Biol, 24, 2017
|
|