7PJF

Inhibiting parasite proliferation using a rationally designed anti-tubulin agent

Summary for 7PJF

• Entry DOI: 10.2210/pdb7pjf/pdb
• Descriptor: Tubulin alpha-1B chain, Tubulin beta-3 chain, Designed ankyrin repeat protein (DARPIN) D1, ... (6 entities in total)
• Functional Keywords: tubulin, microtubules, protozoa, apicomplexa, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 118443.84

Authors

Sharma, A.,Gaillard, N.,Ehrhard, V.A.,Steinmetz, M.O. (deposition date: 2021-08-24, release date: 2021-09-22, Last modification date: 2024-01-31)

• Primary citation: Gaillard, N.,Sharma, A.,Abbaali, I.,Liu, T.,Shilliday, F.,Cook, A.D.,Ehrhard, V.,Bangera, M.,Roberts, A.J.,Moores, C.A.,Morrissette, N.,Steinmetz, M.O.; Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.; Embo Mol Med, 13:e13818-e13818, 2021; PubMed: 34661376; DOI: 10.15252/emmm.202013818

Experimental method

X-RAY DIFFRACTION (1.862 Å)