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PDB: 230 results

5ZG8
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Crystal Structure of TtNRS
Descriptor: Asparagine--tRNA ligase
Authors:Mutharasappan, N, Jain, V, Sharma, A, Manickam, Y, Jeyaraman, J.
Deposit date:2018-03-08
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of TtNRS
To be published
4Z9W
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Structural studies on a non-toxic homologue of type II RIPs from Momordica charantia (bitter gourd)-Native-2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chandran, T, Sharma, A, Vijayan, M.
Deposit date:2015-04-12
Release date:2016-03-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural studies on a non-toxic homologue of type II RIPs from bitter gourd: Molecular basis of non-toxicity, conformational selection and glycan structure.
J.Biosci., 40, 2015
5ZKH
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BU of 5zkh by Molmil
Crystal Structure of N-terminal Domain of Plasmodium falciparum p43
Descriptor: Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43
Authors:Manickam, Y, Sharma, A, Khan, S.
Deposit date:2018-03-23
Release date:2019-04-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.991 Å)
Cite:Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
4ZGR
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Structural studies on a non-toxic homologue of type II RIPs from Momordica charantia (bitter gourd) in complex with T-Antigen.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Chandran, T, Sharma, A, Vijayan, M.
Deposit date:2015-04-23
Release date:2016-03-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural studies on a non-toxic homologue of type II RIPs from bitter gourd: Molecular basis of non-toxicity, conformational selection and glycan structure.
J.Biosci., 40, 2015
6AA0
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BU of 6aa0 by Molmil
Crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in Apo Form
Descriptor: GLYCEROL, Prolyl-tRNA synthetase (ProRS)
Authors:Mishra, S, Kumari, S, Sharma, A, Yogavel, M.
Deposit date:2018-07-16
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational heterogeneity in apo and drug-bound structures of Toxoplasma gondii prolyl-tRNA synthetase.
Acta Crystallogr.,Sect.F, 75, 2019
5XIP
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BU of 5xip by Molmil
Crystal Structure of Eimeria tenella Prolyl-tRNA Synthetase (EtPRS) in complex with Halofuginone
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Jain, V, Manickam, Y, Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5ZDK
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BU of 5zdk by Molmil
Crystal Structure Analysis of TtQRS in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CESIUM ION, CHLORIDE ION, ...
Authors:Mutharasappan, N, Jain, V, Sharma, A, Manickam, Y, Jeyaraman, J.
Deposit date:2018-02-23
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and functional analysis of Glutaminyl-tRNA synthetase (TtGlnRS) from Thermus thermophilus HB8 and its complexes
Int. J. Biol. Macromol., 120, 2018
5X6N
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BU of 5x6n by Molmil
Structure of P. Knowlesi DBL Domain Capable of binding Human Duffy Antigen
Descriptor: Duffy binding protein, SULFATE ION, octyl beta-D-glucopyranoside
Authors:Singh, S.K, Hora, R, Belrhali, H, Chitnis, C, Sharma, A.
Deposit date:2017-02-22
Release date:2017-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain
Nature, 439, 2006
5XIF
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BU of 5xif by Molmil
Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Toxoplasma gondii
Descriptor: CHLORIDE ION, Prolyl-tRNA synthetase (ProRS)
Authors:Jain, V, Manickam, Y, Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIQ
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BU of 5xiq by Molmil
Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with Halofuginone
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Jain, V, Manickam, Y, Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XII
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Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with inhibitor 6
Descriptor: 1,2-ETHANEDIOL, 6-chloranyl-7-fluoranyl-3-[3-[(2R)-3-oxidanylidenepiperidin-2-yl]propyl]quinazolin-4-one, CHLORIDE ION, ...
Authors:Jain, V, Manickam, Y, Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
4JFA
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BU of 4jfa by Molmil
Crystal Structure of Plasmodium falciparum Tryptophanyl-tRNA synthetase
Descriptor: BETA-MERCAPTOETHANOL, POTASSIUM ION, TRYPTOPHAN, ...
Authors:Khan, S, Garg, A, Manickam, Y, Sharma, A.
Deposit date:2013-02-28
Release date:2014-01-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An appended domain results in an unusual architecture for malaria parasite tryptophanyl-tRNA synthetase
Plos One, 8, 2013
6IPA
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BU of 6ipa by Molmil
C-terminal EMAP II-like domain of p43 refined against twinned data
Descriptor: aminoacyl-tRNA synthetase-interacting multifunctional protein p43
Authors:Manickam, Y, Harlos, K, Gupta, S, Sharma, A.
Deposit date:2018-11-02
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein.
Acta Crystallogr D Struct Biol, 76, 2020
5IO9
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X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-08
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IP4
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BU of 5ip4 by Molmil
X-RAY STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin, XA4551 NANOBODY AGAINST C-DCX
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-09
Release date:2016-05-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IN7
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BU of 5in7 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-07
Release date:2016-03-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IOI
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BU of 5ioi by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-08
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
4TWA
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BU of 4twa by Molmil
Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Plasmodium falciparum
Descriptor: CHLORIDE ION, Proline--tRNA ligase, SULFATE ION
Authors:Jain, V, Yogavel, M, Sharma, A.
Deposit date:2014-06-30
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase.
J. Struct. Funct. Genomics, 15, 2014
1OIS
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BU of 1ois by Molmil
YEAST DNA TOPOISOMERASE I, N-TERMINAL FRAGMENT
Descriptor: DNA TOPOISOMERASE I
Authors:Lue, N, Sharma, A, Mondragon, A, Wang, J.C.
Deposit date:1996-09-14
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications.
Structure, 3, 1995
5NCK
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BU of 5nck by Molmil
The Crystal Structure of N-acetylmannosamine kinase in Fusobacterium nucleatum
Descriptor: N-acetylmannosamine kinase
Authors:Caing-Carlsson, R, Sharma, A, Friemann, R, Ramaswamy, S.
Deposit date:2017-03-06
Release date:2017-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structure of N-acetylmannosamine kinase from Fusobacterium nucleatum.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2WZ7
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BU of 2wz7 by Molmil
Crystal structure of the N-terminal domain of E.coli YbgF
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
Authors:Krachler, A.M, Sharma, A, Kleanthous, C.
Deposit date:2009-11-24
Release date:2010-09-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Tola Modulates the Oligomeric Status of Ybgf in the Bacterial Periplasm.
J.Mol.Biol., 403, 2010
3FS3
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BU of 3fs3 by Molmil
Crystal structure of malaria parasite Nucleosome Assembly Protein (NAP)
Descriptor: Nucleosome assembly protein 1, putative
Authors:Gill, J, Yogavel, M, Kumar, A, Belrhali, H, Sharma, A.
Deposit date:2009-01-09
Release date:2009-01-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of malaria parasite nucleosome assembly protein: distinct modes of protein localization and histone recognition.
J.Biol.Chem., 284, 2009
1FFN
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BU of 1ffn by Molmil
CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M)
Descriptor: BETA-2 MICROGLOBULIN, BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A.
Deposit date:2000-07-25
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
2XDJ
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Crystal structure of the N-terminal domain of E.coli YbgF
Descriptor: ACETATE ION, SODIUM ION, UNCHARACTERIZED PROTEIN YBGF
Authors:Krachler, A.M, Sharma, A, Kleanthous, C.
Deposit date:2010-05-04
Release date:2010-09-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Tola Modulates the Oligomeric Status of Ybgf in the Bacterial Periplasm.
J.Mol.Biol., 403, 2010
1FFO
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BU of 1ffo by Molmil
CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH SYNTHETIC PEPTIDE GP33 (C9M/K1A)
Descriptor: BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ...
Authors:Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A.
Deposit date:2000-07-25
Release date:2002-12-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Peptidic termini play a significant role in TCR recognition.
J.Immunol., 169, 2002

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