4WA8
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8U9Y
| CryoEM structure of neutralizing antibody HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2_New interface | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | 著者 | Shahid, S, Liqun, J, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-09-20 | 公開日 | 2024-09-25 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | CryoEM structure of neutralizing antibody HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2_New interface To Be Published
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8TGV
| CryoEM structure of Fab HC84.26-HCV E2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HC84.26 Heavy chain, ... | 著者 | Shahid, S, Liqun, J, LIu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-07-13 | 公開日 | 2024-07-24 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | CryoEM structure of Fab HC84.26-HCV E2 complex To Be Published
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8TGZ
| CryoEM structure of neutralizing antibody HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HC84.26 Heavy chain, ... | 著者 | Shahid, S, Liqun, J, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-07-13 | 公開日 | 2024-07-24 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | CryoEM structure of neutralizing antibody HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
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8THZ
| CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CBH-7 Heavy chain, ... | 著者 | Shahid, S, Jiang, L, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-07-18 | 公開日 | 2024-07-24 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
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8TXQ
| CryoEM structure of non-neutralizing antibody CBH-4B in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | CBH-4B Heavy chain, CBH-4B Light chain, envelope glycoprotein E2 | 著者 | Shahid, S, Liqun, J, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-08-24 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | CryoEM structure of non-neutralizing antibody CBH-4B in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
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8TZY
| CryoEM structure of non-neutralizing bivalent antibody CBH-4B in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | CBH4B Heavy chain, CBH4B Light chain, envelope glycoprotein E2 | 著者 | Shahid, S, Liqun, J, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-08-28 | 公開日 | 2024-09-04 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | CryoEM structure of non-neutralizing bivalent antibody CBH-4B in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
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5B6J
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5ZK0
| Crystal structure of Peptidyl-tRNA hydrolase mutant -M71A from Vibrio cholerae | 分子名称: | Peptidyl-tRNA hydrolase, SODIUM ION | 著者 | Shahid, S, Kabra, A, Pal, R.K, Arora, A. | 登録日 | 2018-03-22 | 公開日 | 2018-06-06 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Role of methionine 71 in substrate recognition and structural integrity of bacterial peptidyl-tRNA hydrolase. Biochim. Biophys. Acta, 1866, 2018
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5IKE
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5IMB
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4Z86
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4ZXP
| Crystal structure of Peptidyl- tRNA Hydrolase from Vibrio cholerae | 分子名称: | CITRATE ANION, Peptidyl-tRNA hydrolase | 著者 | Shahid, S, Pal, R.K, Kabra, A, Yadav, R, Kumar, A, Arora, A. | 登録日 | 2015-05-20 | 公開日 | 2016-06-22 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Unraveling the stereochemical and dynamic aspects of the catalytic site of bacterial peptidyl-tRNA hydrolase. RNA, 23, 2017
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6X9X
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5GVZ
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5IVP
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5EKT
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8TFE
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4CV3
| Crystal structure of E. coli FabI in complex with NADH and PT166 | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-hexyl-1-methyl-5-(2-methylphenoxy)pyridin-4(1H)-one, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] | 著者 | Eltschkner, S, Schiebel, J, Chang, A, Shah, S, Tonge, P.J, Kisker, C. | 登録日 | 2014-03-22 | 公開日 | 2014-04-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Rational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (Acp) Reductase Inhibitor. J.Biol.Chem., 289, 2014
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4CV0
| Crystal structure of S. aureus FabI in complex with NADPH and CG400549 (small unit cell) | 分子名称: | 1,2-ETHANEDIOL, 1-(3-amino-2-methylbenzyl)-4-[2-(thiophen-2-yl)ethoxy]pyridin-2(1H)-one, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], ... | 著者 | Schiebel, J, Chang, A, Shah, S, Tonge, P.J, Kisker, C. | 登録日 | 2014-03-22 | 公開日 | 2014-04-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Rational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (Acp) Reductase Inhibitor. J.Biol.Chem., 289, 2014
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4CUZ
| Crystal structure of S. aureus FabI in complex with NADPH and PT173 | 分子名称: | 1-(3-amino-2-methylbenzyl)-4-hexylpyridin-2(1H)-one, ENOYL-ACP REDUCTASE MOLECULE ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiebel, J, Chang, A, Shah, S, Tonge, P.J, Kisker, C. | 登録日 | 2014-03-22 | 公開日 | 2014-04-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Rational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (Acp) Reductase Inhibitor. J.Biol.Chem., 289, 2014
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1CE5
| BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZAMIDINE | 分子名称: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Ota, N, Stroupe, C, Ferreira-Da-Silva, J.M.S, Shah, S.S, Mares-Guia, M, Brunger, A.T. | 登録日 | 1999-03-16 | 公開日 | 1999-03-23 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: relative free energy of binding of trypsin to benzamidine and benzylamine. Proteins, 37, 1999
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2BZA
| BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZYLAMINE | 分子名称: | BENZYLAMINE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Ota, N, Stroupe, C, Ferreira-Da-Silva, J.M.S, Shah, S.S, Mares-Guia, M, Brunger, A.T. | 登録日 | 1999-03-16 | 公開日 | 1999-03-23 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: relative free energy of binding of trypsin to benzamidine and benzylamine. Proteins, 37, 1999
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3L24
| Crystal Structure of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase in Complex with Inhibitors | 分子名称: | GLYCOLIC ACID, MANGANESE (II) ION, Xaa-Pro dipeptidase | 著者 | Vyas, N.K, Nichitenko, A, Rastogi, V.K, Shah, S.S, Quiocho, F.A. | 登録日 | 2009-12-14 | 公開日 | 2010-01-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase. Biochemistry, 49, 2010
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3OV6
| CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) | 分子名称: | 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J. | 登録日 | 2010-09-15 | 公開日 | 2011-01-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation Immunity, 33, 2010
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