3L24

Crystal Structure of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase in Complex with Inhibitors

Summary for 3L24

• Entry DOI: 10.2210/pdb3l24/pdb
• Descriptor: Xaa-Pro dipeptidase, MANGANESE (II) ION, GLYCOLIC ACID, ... (4 entities in total)
• Functional Keywords: pita-bread, detoxification, dipeptidase, hydrolase, manganese, metal-binding, metalloprotease, protease
• Biological source: Alteromonas sp.
• Total number of polymer chains: 3
• Total formula weight: 178278.21

Authors

Vyas, N.K.,Nichitenko, A.,Rastogi, V.K.,Shah, S.S.,Quiocho, F.A. (deposition date: 2009-12-14, release date: 2010-01-26, Last modification date: 2023-11-15)

• Primary citation: Vyas, N.K.,Nickitenko, A.,Rastogi, V.K.,Shah, S.S.,Quiocho, F.A.; Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase.; Biochemistry, 49:547-559, 2010; PubMed: 20000741; DOI: 10.1021/bi9011989

Experimental method

X-RAY DIFFRACTION (2.3 Å)