7QNE
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![BU of 7qne by Molmil](/molmil-images/mine/7qne) | Cryo-EM structure of human full-length synaptic alpha1beta3gamma2 GABA(A)R in complex with Ro15-4513 and megabody Mb38 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QNC
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![BU of 7qnc by Molmil](/molmil-images/mine/7qnc) | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with THIP (gaboxadol), histamine and nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN5
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![BU of 7qn5 by Molmil](/molmil-images/mine/7qn5) | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with nanobody Nb25 | 分子名称: | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN7
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![BU of 7qn7 by Molmil](/molmil-images/mine/7qn7) | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25 | 分子名称: | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QND
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![BU of 7qnd by Molmil](/molmil-images/mine/7qnd) | Cryo-EM structure of human full-length extrasynaptic beta3delta GABA(A)R in complex with THIP (gaboxadol), histamine and nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QNB
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![BU of 7qnb by Molmil](/molmil-images/mine/7qnb) | Cryo-EM structure of human full-length beta3gamma2 GABA(A)R in complex with GABA and nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QNA
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![BU of 7qna by Molmil](/molmil-images/mine/7qna) | Cryo-EM structure of human full-length alpha4beta3gamma2 GABA(A)R in complex with GABA and nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN8
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![BU of 7qn8 by Molmil](/molmil-images/mine/7qn8) | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with histamine and nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN6
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![BU of 7qn6 by Molmil](/molmil-images/mine/7qn6) | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN9
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![BU of 7qn9 by Molmil](/molmil-images/mine/7qn9) | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25 in a pre-open/closed state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7A5V
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![BU of 7a5v by Molmil](/molmil-images/mine/7a5v) | CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | 登録日 | 2020-08-22 | 公開日 | 2020-11-18 | 最終更新日 | 2020-11-25 | 実験手法 | ELECTRON MICROSCOPY (1.7 Å) | 主引用文献 | Single-particle cryo-EM at atomic resolution. Nature, 587, 2020
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7A4M
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![BU of 7a4m by Molmil](/molmil-images/mine/7a4m) | Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A | 分子名称: | FE (III) ION, Ferritin heavy chain, ZINC ION | 著者 | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | 登録日 | 2020-08-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (1.22 Å) | 主引用文献 | Single-particle cryo-EM at atomic resolution. Nature, 587, 2020
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