2H59
| Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose | Descriptor: | (2S,3S,4R,5S)-2-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-4,5-DIHYDROXYTETRAHYDROFURAN-3-YL ACETATE, ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, ... | Authors: | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | Deposit date: | 2006-05-25 | Release date: | 2006-09-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
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2H4H
| Sir2 H116Y mutant-p53 peptide-NAD | Descriptor: | Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | Deposit date: | 2006-05-24 | Release date: | 2006-09-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
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2H4J
| Sir2-deacetylated peptide (from enzymatic turnover in crystal) | Descriptor: | 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, NAD-dependent deacetylase, ... | Authors: | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | Deposit date: | 2006-05-24 | Release date: | 2006-09-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
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2H4F
| Sir2-p53 peptide-NAD+ | Descriptor: | Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | Deposit date: | 2006-05-24 | Release date: | 2006-09-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
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