3IPO
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![BU of 3ipo by Molmil](/molmil-images/mine/3ipo) | Crystal structure of YnjE | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... | Authors: | Haenzelmann, P, Kuper, J, Schindelin, H. | Deposit date: | 2009-08-18 | Release date: | 2009-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains. Protein Sci., 18, 2009
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3IPP
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![BU of 3ipp by Molmil](/molmil-images/mine/3ipp) | crystal structure of sulfur-free YnjE | Descriptor: | GLYCEROL, PHOSPHATE ION, Putative thiosulfate sulfurtransferase ynjE, ... | Authors: | Haenzelmann, P, Kuper, J, Schindelin, H. | Deposit date: | 2009-08-18 | Release date: | 2009-12-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains. Protein Sci., 18, 2009
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5L6H
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![BU of 5l6h by Molmil](/molmil-images/mine/5l6h) | Uba1 in complex with Ub-ABPA3 covalent adduct | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2016-05-30 | Release date: | 2017-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme. Structure, 25, 2017
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5L6I
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![BU of 5l6i by Molmil](/molmil-images/mine/5l6i) | Uba1 in complex with Ub-MLN4924 covalent adduct | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2016-05-30 | Release date: | 2017-06-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme. Structure, 25, 2017
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6ZHU
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![BU of 6zhu by Molmil](/molmil-images/mine/6zhu) | Yeast Uba1 in complex with Ubc3 and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2020-06-23 | Release date: | 2022-01-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system To Be Published
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5L6J
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![BU of 5l6j by Molmil](/molmil-images/mine/5l6j) | Uba1 in complex with Ub-MLN7243 covalent adduct | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2016-05-30 | Release date: | 2017-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme. Structure, 25, 2017
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6ZQH
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![BU of 6zqh by Molmil](/molmil-images/mine/6zqh) | Yeast Uba1 in complex with ubiquitin | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2020-07-09 | Release date: | 2020-11-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chemistry, 27, 2021
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6YK0
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![BU of 6yk0 by Molmil](/molmil-images/mine/6yk0) | |
6YJZ
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![BU of 6yjz by Molmil](/molmil-images/mine/6yjz) | |
6YK1
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![BU of 6yk1 by Molmil](/molmil-images/mine/6yk1) | |
6ZHS
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![BU of 6zhs by Molmil](/molmil-images/mine/6zhs) | Uba1 bound to two E2 (Ubc13) molecules | Descriptor: | GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2020-06-23 | Release date: | 2022-01-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
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6ZHT
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![BU of 6zht by Molmil](/molmil-images/mine/6zht) | Uba1-Ubc13 disulfide mediated complex | Descriptor: | CHLORIDE ION, GLYCEROL, Ubiquitin-activating enzyme E1 1, ... | Authors: | Schaefer, A, Misra, M, Schindelin, H. | Deposit date: | 2020-06-23 | Release date: | 2022-01-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
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3BOA
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![BU of 3boa by Molmil](/molmil-images/mine/3boa) | |
3M63
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![BU of 3m63 by Molmil](/molmil-images/mine/3m63) | |
3M62
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![BU of 3m62 by Molmil](/molmil-images/mine/3m62) | |
5YPW
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![BU of 5ypw by Molmil](/molmil-images/mine/5ypw) | Crystal structure of IlvN.Val-1b | Descriptor: | Acetolactate synthase isozyme 1 small subunit, VALINE | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | Deposit date: | 2017-11-03 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
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7PUX
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![BU of 7pux by Molmil](/molmil-images/mine/7pux) | Structure of p97 N-D1(L198W) in complex with Fragment TROLL2 | Descriptor: | (1S)-2-amino-1-(4-bromophenyl)ethan-1-ol, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bothe, S, Schindelin, H. | Deposit date: | 2021-10-01 | Release date: | 2022-12-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97 Commun Chem, 5, 2022
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3GAE
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![BU of 3gae by Molmil](/molmil-images/mine/3gae) | Crystal Structure of PUL | Descriptor: | CHLORIDE ION, GLYCEROL, Protein DOA1 | Authors: | Zhao, G, Schindelin, H, Lennarz, W.J. | Deposit date: | 2009-02-17 | Release date: | 2009-12-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation Proc.Natl.Acad.Sci.USA, 106, 2009
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3CMM
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![BU of 3cmm by Molmil](/molmil-images/mine/3cmm) | Crystal Structure of the Uba1-Ubiquitin Complex | Descriptor: | PROLINE, Ubiquitin, Ubiquitin-activating enzyme E1 1 | Authors: | Lee, I, Schindelin, H. | Deposit date: | 2008-03-23 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes. Cell(Cambridge,Mass.), 134, 2008
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5C1A
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![BU of 5c1a by Molmil](/molmil-images/mine/5c1a) | p97-N750D/R753D/M757D/Q760D in complex with ATP-gamma-S | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | Authors: | Haenzelmann, P, Schindelin, H. | Deposit date: | 2015-06-13 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97. Structure, 24, 2016
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4NNJ
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![BU of 4nnj by Molmil](/molmil-images/mine/4nnj) | |
5YPP
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![BU of 5ypp by Molmil](/molmil-images/mine/5ypp) | Crystal structure of IlvN.Val-1a | Descriptor: | ACETATE ION, Acetolactate synthase isozyme 1 small subunit, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | Deposit date: | 2017-11-02 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
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6FGC
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![BU of 6fgc by Molmil](/molmil-images/mine/6fgc) | Crystal structure of Gephyrin E domain in complex with Artesunate | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | Authors: | Kasaragod, V.B, Schindelin, H. | Deposit date: | 2018-01-10 | Release date: | 2019-01-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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6GXY
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![BU of 6gxy by Molmil](/molmil-images/mine/6gxy) | Tryparedoxin from Trypanosoma brucei in complex with CFT | Descriptor: | 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, Tryparedoxin | Authors: | Bader, N, Wagner, A, Hellmich, U, Schindelin, H. | Deposit date: | 2018-06-27 | Release date: | 2019-01-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes. Angew. Chem. Int. Ed. Engl., 58, 2019
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6FGD
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![BU of 6fgd by Molmil](/molmil-images/mine/6fgd) | |