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PDB: 57 results

2F9D
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BU of 2f9d by Molmil
2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M.
Deposit date:2005-12-05
Release date:2006-01-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
3ENB
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BU of 3enb by Molmil
Crystal Structure of PRP8 core domain IV
Descriptor: Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
Deposit date:2008-09-25
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Nat.Struct.Mol.Biol., 15, 2008
2F9J
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BU of 2f9j by Molmil
3.0 angstrom resolution structure of a Y22M mutant of the spliceosomal protein p14 bound to a region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, MacMillan, A.M.
Deposit date:2005-12-06
Release date:2006-01-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
3LQV
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BU of 3lqv by Molmil
Branch Recognition by SF3b14
Descriptor: ADENINE, Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, MacMillan, A.M.
Deposit date:2010-02-10
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Branch Recognition by SF3b14
Rna, 17, 2011
3LRU
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BU of 3lru by Molmil
hPRP8 Non-Native Subdomain
Descriptor: Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
Deposit date:2010-02-11
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Context-dependent remodeling of structure in two large protein fragments.
J.Mol.Biol., 402, 2010
5TVP
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BU of 5tvp by Molmil
SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-11-09
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Science, 357, 2017
3QRR
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BU of 3qrr by Molmil
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex
Descriptor: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*(23G))-3')
Authors:Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.099 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
3QRP
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BU of 3qrp by Molmil
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product mimic complex
Descriptor: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*(PGP))-3'), RNA (5'-R(P*(U5P)P*GP*UP*GP*GP*GP*G)-3'), ...
Authors:Schellenberg, M.J, Gesner, E.M, Garside, E.L, MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
3QRQ
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BU of 3qrq by Molmil
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex
Descriptor: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*GP*A)-3')
Authors:Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
5TVQ
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BU of 5tvq by Molmil
Mouse Tdp2 catalytic domain bound to SUMO2
Descriptor: ACETATE ION, CALCIUM ION, Small ubiquitin-related modifier 2, ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-11-09
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Science, 357, 2017
5HT2
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BU of 5ht2 by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA, ...
Authors:Schellenberg, M.J, Vilas, C.K, Williams, R.S.
Deposit date:2016-01-26
Release date:2016-04-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INP
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BU of 5inp by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mn2+ complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), MANGANESE (II) ION, ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.947 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INN
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BU of 5inn by Molmil
Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Schellenberg, M.J, Appel, C.D, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INO
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BU of 5ino by Molmil
Human Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex
Descriptor: DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), SULFATE ION, Tyrosyl-DNA phosphodiesterase 2
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.205 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INL
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BU of 5inl by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with deoxyadenosine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*AP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ...
Authors:Schellenberg, M.J, Vilas, C.K, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INQ
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BU of 5inq by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Ca2+ complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INK
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BU of 5ink by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-abasic/THF-Mg2+ complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*(3DR)P*CP*GP*AP*AP*TP*TP*CP*G)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INM
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BU of 5inm by Molmil
Mouse Tdp2 protein, apo state with variable DNA-binding grasp conformations
Descriptor: GLYCEROL, MAGNESIUM ION, SULFATE ION, ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-03-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
6P0B
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BU of 6p0b by Molmil
Human DNA Ligase 1 (E346A/E592A) Bound to an Adenylated, dideoxy Terminated DNA nick with 200 mM Mg2+
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0A
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BU of 6p0a by Molmil
Human DNA Ligase 1 Bound to an Adenylated, dideoxy Terminated DNA nick with 2 mM Mg2+
Descriptor: ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0D
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BU of 6p0d by Molmil
Human DNA Ligase 1 (E346A/E592A) Bound to an Adenylated, hydroxyl terminated DNA nick
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0C
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BU of 6p0c by Molmil
Human DNA Ligase 1 Bound to an Adenylated, hydroxyl terminated DNA nick in EDTA
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Tumbale, P.S, Riccio, A.A, Williams, R.S.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P09
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BU of 6p09 by Molmil
Human DNA Ligase 1 Bound to an Adenylated, dideoxy Terminated DNA nick with 200 mM Mg2+
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0E
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BU of 6p0e by Molmil
Human DNA Ligase 1 (E346A,E592A) bound to adenylated DNA containing an 8-oxo guanine:adenine base-pair
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6Q00
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BU of 6q00 by Molmil
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1
Descriptor: POTASSIUM ION, Tyrosyl-DNA phosphodiesterase 2, Ubiquitin
Authors:Schellenberg, M.J, Krahn, J.M, Williams, R.S.
Deposit date:2019-08-01
Release date:2020-04-29
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
Nucleic Acids Res., 48, 2020

 

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