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PDB: 9 件
5DJ4
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BU of 5dj4 by Molmil
Leucine-bound Sestrin2 from Homo sapiens
分子名称: LEUCINE, Sestrin-2
著者Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
登録日2015-09-01
公開日2015-11-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Science, 351, 2016
5I2C
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BU of 5i2c by Molmil
Arginine-bound CASTOR1 from Homo sapiens
分子名称: ACETATE ION, ARGININE, GATS-like protein 3
著者Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
登録日2016-02-08
公開日2016-08-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Nature, 536, 2016
5T0N
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BU of 5t0n by Molmil
Pseudo-apo structure of Sestrin2 at 3.0 angstrom resolution
分子名称: LEUCINE, Sestrin-2
著者Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
登録日2016-08-16
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献The apo-structure of the leucine sensor Sestrin2 is still elusive.
Sci.Signal., 9, 2016
6WEO
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BU of 6weo by Molmil
IL-22 Signaling Complex with IL-22R1 and IL-10Rbeta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Saxton, R.A, Jude, K.M, Henneberg, L.T, Garcia, K.C.
登録日2020-04-02
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.
Immunity, 54, 2021
6X93
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BU of 6x93 by Molmil
Interleukin-10 signaling complex with IL-10RA and IL-10RB
分子名称: Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta
著者Saxton, R.A, Tsutsumi, N, Gati, C, Garcia, K.C.
登録日2020-06-02
公開日2021-03-17
最終更新日2021-03-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.
Science, 371, 2021
8DHA
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BU of 8dha by Molmil
Leptin-bound leptin receptor complex- focused interaction
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8DH8
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BU of 8dh8 by Molmil
Leptin-bound leptin receptor complex-full ECD
分子名称: Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8DH9
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BU of 8dh9 by Molmil
Leptin-bound leptin receptor complex-D3-D7
分子名称: Leptin, Leptin receptor
著者Saxton, R.A, Caveney, N.A, Garcia, K.C.
登録日2022-06-25
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural insights into the mechanism of leptin receptor activation.
Nat Commun, 14, 2023
8EWY
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BU of 8ewy by Molmil
Structure of Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain
分子名称: ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Interferon lambda receptor 1, ...
著者Caveney, N.A, Saxton, R.A, Waghray, D, Garcia, K.C.
登録日2022-10-24
公開日2023-03-08
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structural basis of Janus kinase trans-activation.
Cell Rep, 42, 2023

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件を2024-07-24に公開中

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