5DJ4

Leucine-bound Sestrin2 from Homo sapiens

Summary for 5DJ4

Entry DOI	10.2210/pdb5dj4/pdb
Descriptor	Sestrin-2, LEUCINE (3 entities in total)
Functional Keywords	mtor, leucine, amino-acid, sensing, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	5
Total formula weight	273458.70
Authors	Saxton, R.A.,Knockenhauer, K.E.,Schwartz, T.U. (deposition date: 2015-09-01, release date: 2015-11-25, Last modification date: 2024-03-06)
Primary citation	Saxton, R.A.,Knockenhauer, K.E.,Wolfson, R.L.,Chantranupong, L.,Pacold, M.E.,Wang, T.,Schwartz, T.U.,Sabatini, D.M. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. Science, 351:53-58, 2016 Cited by PubMed: 26586190 DOI: 10.1126/science.aad2087 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.697 Å)

Structure validation