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PDB: 611 件

6PES
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Cryo-EM structure of alpha-synuclein H50Q Wide Fibril
分子名称: Alpha-synuclein
著者Boyer, D.R, Li, B, Sawaya, M.R, Jiang, L, Eisenberg, D.S.
登録日2019-06-20
公開日2019-11-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs.
Nat.Struct.Mol.Biol., 26, 2019
6PIL
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Antibody scFv-M204 monomeric state
分子名称: CHLORIDE ION, scFv-M204 antibody
著者Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S.
登録日2019-06-26
公開日2020-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease.
J.Biol.Chem., 295, 2020
6PQ5
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AGAAAA segment 113-118 from human prion
分子名称: MALONATE ION, Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
6PEO
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Cryo-EM structure of alpha-synuclein H50Q Narrow Fibril
分子名称: Alpha-synuclein
著者Boyer, D.R, Li, B, Sawaya, M.R, Jiang, L, Eisenberg, D.S.
登録日2019-06-20
公開日2019-11-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs.
Nat.Struct.Mol.Biol., 26, 2019
6PK8
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BU of 6pk8 by Molmil
Antibody scFv-M204 dimeric state
分子名称: SULFATE ION, scFv-M204 antibody
著者Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S.
登録日2019-06-28
公開日2020-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease.
J.Biol.Chem., 295, 2020
6PQA
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GAVVGG segment 119-124 from human prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
6PSC
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Antibody scFv-M204 trimeric state
分子名称: scFv-M204 antibody
著者Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S.
登録日2019-07-12
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease.
J.Biol.Chem., 295, 2020
6O4J
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BU of 6o4j by Molmil
Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation
分子名称: Amyloid-beta precursor protein
著者Griner, S.L, Sawaya, M.R, Rodriguez, J.A, Cascio, D, Gonen, T.
登録日2019-02-28
公開日2019-10-30
最終更新日2024-10-23
実験手法ELECTRON CRYSTALLOGRAPHY (1.402 Å)
主引用文献Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau.
Elife, 8, 2019
2A4T
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Crystal structure of spin labeled T4 Lysozyme (V131R7)
分子名称: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
著者Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
登録日2005-06-29
公開日2006-06-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of spin labeled T4 Lysozyme (V131R7
To be Published
1ZUR
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Crystal structure of spin labeled T4 Lysozyme (V131R1F)
分子名称: CHLORIDE ION, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
登録日2005-05-31
公開日2006-10-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of spin labeled T4 Lysozyme (V131R1F)
To be Published
1ZWN
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Crystal structure of spin labeled T4 Lysozyme (V131R1B)
分子名称: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
著者Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
登録日2005-06-03
公開日2006-10-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of spin labeled T4 Lysozyme (V131R1B)
To be Published
2PY8
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BU of 2py8 by Molmil
RbcX
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CHLORIDE ION, Hypothetical protein rbcX
著者Tanaka, S, Sawaya, M.R, Kerfeld, C.A, Yeates, T.O.
登録日2007-05-15
公開日2007-10-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the RuBisCO chaperone RbcX from Synechocystis sp. PCC6803.
Acta Crystallogr.,Sect.D, 63, 2007
2RCF
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BU of 2rcf by Molmil
Carboxysome Shell protein, OrfA from H. Neapolitanus
分子名称: CHLORIDE ION, GLYCEROL, Unidentified carboxysome polypeptide
著者Kerfeld, C.A, Sawaya, M.R, Yeates, T.O.
登録日2007-09-19
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Atomic-level models of the bacterial carboxysome shell.
Science, 319, 2008
2RIF
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BU of 2rif by Molmil
CBS domain protein PAE2072 from Pyrobaculum aerophilum complexed with AMP
分子名称: ADENOSINE MONOPHOSPHATE, CESIUM ION, Conserved protein with 2 CBS domains
著者Lee, T.M, King, N.P, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2007-10-10
公開日2008-06-17
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures and Functional Implications of an AMP-Binding Cystathionine beta-Synthase Domain Protein from a Hyperthermophilic Archaeon.
J.Mol.Biol., 380, 2008
6T19
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BU of 6t19 by Molmil
Structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals soaked with DTT at pH 7
分子名称: SODIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
6T1A
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BU of 6t1a by Molmil
Structure of mosquitocidal Cyt1Aa protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 10
分子名称: CALCIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
6T1C
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BU of 6t1c by Molmil
Structure of the C7S mutant of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7
分子名称: SODIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
6T14
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BU of 6t14 by Molmil
Native structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7
分子名称: SODIUM ION, Type-1Aa cytolytic delta-endotoxin
著者Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P.
登録日2019-10-03
公開日2020-10-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
1F1F
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BU of 1f1f by Molmil
CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM ARTHROSPIRA MAXIMA
分子名称: CYTOCHROME C6, HEME C
著者Kerfeld, C.A, Serag, A.A, Sawaya, M.R, Krogmann, D.W, Yeates, T.O.
登録日2000-05-18
公開日2001-08-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima.
Biochemistry, 40, 2001
7ICE
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BU of 7ice by Molmil
DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CACL2
分子名称: DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), DNA (5'-D(P*CP*AP*GP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
1F1C
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CRYSTAL STRUCTURE OF CYTOCHROME C549
分子名称: CYTOCHROME C549, HEME C
著者Kerfeld, C.A, Sawaya, M.R, Yeates, T.O, Krogmann, D.W.
登録日2000-05-18
公開日2001-08-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima.
Biochemistry, 40, 2001
2RIH
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BU of 2rih by Molmil
CBS domain protein PAE2072 from Pyrobaculum aerophilum
分子名称: ACETIC ACID, Conserved protein with 2 CBS domains, SULFATE ION
著者Lee, T.M, King, N.P, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2007-10-10
公開日2008-06-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures and Functional Implications of an AMP-Binding Cystathionine beta-Synthase Domain Protein from a Hyperthermophilic Archaeon
J.Mol.Biol., 380, 2008
2QW7
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BU of 2qw7 by Molmil
Carboxysome Subunit, CcmL
分子名称: Carbon dioxide concentrating mechanism protein ccmL, GLYCEROL
著者Tanaka, S, Sawaya, M.R, Kerfeld, C.A, Yeates, T.O.
登録日2007-08-09
公開日2008-03-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atomic-level models of the bacterial carboxysome shell.
Science, 319, 2008
1Y67
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BU of 1y67 by Molmil
Crystal Structure of Manganese Superoxide Dismutase from Deinococcus radiodurans
分子名称: FE (III) ION, Manganese Superoxide dismutase
著者Chan, S, Tanaka, S, Sawaya, M.R, Perry, L.J.
登録日2004-12-03
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献Crystal Structure of Manganese Superoxide Dismutase from Deinococcus radiodurans
To be Published
1YJO
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Structure of NNQQNY from yeast prion Sup35 with zinc acetate
分子名称: ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION
著者Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
登録日2005-01-15
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005

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件を2024-11-06に公開中

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