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PDB: 2547 results

8UHG
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BU of 8uhg by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Vos, S.M, Su, B.G.
Deposit date:2023-10-09
Release date:2024-03-20
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
4Q7V
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BU of 4q7v by Molmil
Crystal structure of 1-hydroxy-5-methylpyridine-2(1H)-thione bound to human carbonic anhydrase II
Descriptor: 1-hydroxy-5-methylpyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Martin, D.P, Cohen, S.M.
Deposit date:2014-04-25
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q83
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BU of 4q83 by Molmil
Crystal structure of 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II
Descriptor: 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ...
Authors:Martin, D.P, Cohen, S.M.
Deposit date:2014-04-25
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q8X
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BU of 4q8x by Molmil
Crystal structure of 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II
Descriptor: 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Martin, D.P, Cohen, S.M.
Deposit date:2014-04-28
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
8UIS
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BU of 8uis by Molmil
Structure of transcription complex Pol II-DSIF-NELF-TFIIS
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Su, B.G, Vos, S.M.
Deposit date:2023-10-10
Release date:2024-03-20
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
8UHA
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BU of 8uha by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - tilted
Descriptor: DNA (28-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ...
Authors:Vos, S.M, Su, B.G.
Deposit date:2023-10-08
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
3GQV
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BU of 3gqv by Molmil
Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP
Descriptor: Enoyl reductase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ames, B.D, Smith, P.T, Ma, S.M, Kaake, R, Wong, E.W, Wong, S.K, Xie, X, Li, J.W, Vederas, J.C, Tang, Y, Tsai, S.-C.
Deposit date:2009-03-24
Release date:2009-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:biosynthesis of Lovastatin: Crystal structure and biochemical studies of LOVC, A trans-acting polyketide enoyl reductase
To be Published
8UHD
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BU of 8uhd by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
Authors:Su, B.G, Vos, S.M.
Deposit date:2023-10-08
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
2BG7
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BU of 2bg7 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Descriptor: BETA-LACTAMASE II, GLYCEROL, SULFATE ION, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-17
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2F9C
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BU of 2f9c by Molmil
Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6
Descriptor: CESIUM ION, Hypothetical protein YDCK
Authors:Benach, J, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, H, Cooper, B, Acton, X.T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-12-05
Release date:2005-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of YDCK from Salmonella cholerae NESG target SCR6.
To be Published
3LS0
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BU of 3ls0 by Molmil
Crystal Structure of Cyanobacterial PsbQ from Synechocystis sp. PCC 6803
Descriptor: Sll1638 protein
Authors:Jackson, S.A, Fagerlund, R.D, Wilbanks, S.M, Eaton-Rye, J.J.
Deposit date:2010-02-12
Release date:2010-03-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of PsbQ from Synechocystis sp. PCC 6803 at 1.8 A: Implications for Binding and Function in Cyanobacterial Photosystem II
Biochemistry, 49, 2010
2BGG
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BU of 2bgg by Molmil
The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex.
Descriptor: 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ...
Authors:Parker, J.S, Roe, S.M, Barford, D.
Deposit date:2004-12-22
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex
Nature, 434, 2005
3HRU
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BU of 3hru by Molmil
Crystal Structure of ScaR with bound Zn2+
Descriptor: Metalloregulator ScaR, SULFATE ION, ZINC ION
Authors:Stoll, K.E, Draper, W.E, Kliegman, J.I, Golynskiy, M.V, Brew-Appiah, R.A.T, Brown, H.K, Breyer, W.A, Jakubovics, N.S, Jenkinson, H.F, Brennan, R.B, Cohen, S.M, Glasfeld, A.
Deposit date:2009-06-09
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
4MLX
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BU of 4mlx by Molmil
Structure of a bidentate 3-hydroxy-4H-pyran-4-thione ligand bound to hCAII
Descriptor: 5-hydroxy-2-methyl-4H-pyran-4-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Martin, D.P, Cohen, S.M.
Deposit date:2013-09-06
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:'Unconventional' coordination chemistry by metal chelating fragments in a metalloprotein active site.
J.Am.Chem.Soc., 136, 2014
2HDK
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BU of 2hdk by Molmil
Crystal Structure of Cys315Ala-Cys318Ala Mutant of Human Mitochondrial Branched Chain Aminotransferase
Descriptor: 2-OXO-4-METHYLPENTANOIC ACID, ACETIC ACID, Branched-chain-amino-acid aminotransferase, ...
Authors:Yennawar, N.H, Hutson, S.M.
Deposit date:2006-06-20
Release date:2006-10-24
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS.
J.Biol.Chem., 281, 2006
4Q99
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BU of 4q99 by Molmil
Crystal structure of 2-mercapto-4-methylphenol bound to human carbonic anhydrase II
Descriptor: 4-methyl-2-sulfanylphenol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Martin, D.P, Cohen, S.M.
Deposit date:2014-04-29
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
2GWL
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BU of 2gwl by Molmil
Crystal structure of the Salmonella SpvB ATR Domain in complex with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 65 kDa virulence protein
Authors:Stebbins, C.E, Margarit, S.M.
Deposit date:2006-05-04
Release date:2006-08-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
1SKT
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BU of 1skt by Molmil
SOLUTION STRUCTURE OF APO N-DOMAIN OF TROPONIN C, NMR, 40 STRUCTURES
Descriptor: TROPONIN-C
Authors:Tsuda, S, Miura, A, Gagne, S.M, Spyracopoulos, L, Sykes, B.D.
Deposit date:1998-04-06
Release date:1998-12-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Low-temperature-induced structural changes in the Apo regulatory domain of skeletal muscle troponin C.
Biochemistry, 38, 1999
2BG2
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BU of 2bg2 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in the buffer. 1mM DTT and 1mM TCEP- HCl were used as reducing agents. Cys221 is reduced.
Descriptor: BETA-LACTAMASE II, CHLORIDE ION, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-16
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism.
Biochemistry, 44, 2005
2FFG
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BU of 2ffg by Molmil
Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360.
Descriptor: ykuJ
Authors:Kuzin, A.P, Abashidze, M, Forouhar, F, Vorobiev, S.M, Ho, C.K, Janjua, H, Cunningham, K, Conover, K, Ma, L.C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-12-19
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360.
To be Published
2BFZ
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BU of 2bfz by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
Descriptor: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
Authors:Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
Deposit date:2004-12-16
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
4Q6A
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BU of 4q6a by Molmil
Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH
Descriptor: ACETATE ION, Dihydrofolate reductase, GLYCEROL, ...
Authors:Reeve, S.M, Anderson, A.C.
Deposit date:2014-04-21
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Protein design algorithms predict viable resistance to an experimental antifolate.
Proc.Natl.Acad.Sci.USA, 112, 2015
2EW0
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BU of 2ew0 by Molmil
X-ray Crystal Structure of Protein Q6FF54 from Acinetobacter sp. ADP1. Northeast Structural Genomics Consortium Target AsR1.
Descriptor: SULFATE ION, hypothetical protein ACIAD0353
Authors:Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Forouhar, F, Acton, T, Xiao, R, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-11-01
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel x-ray structure of hypothetical protein Q6FF54 at the resolution 1.4 A. Northeast Structural Genomics target AsR1.
TO BE PUBLISHED
3MAN
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BU of 3man by Molmil
MANNOHEXAOSE COMPLEX OF THERMOMONOSPORA FUSCA BETA-MANNANASE
Descriptor: PROTEIN (BETA-MANNANASE), beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose
Authors:Hilge, M, Gloor, S.M, Piontek, K.
Deposit date:1998-08-12
Release date:1999-08-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution native and complex structures of thermostable beta-mannanase from Thermomonospora fusca - substrate specificity in glycosyl hydrolase family 5.
Structure, 6, 1998
3IG4
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BU of 3ig4 by Molmil
Structure of a putative aminopeptidase P from Bacillus anthracis
Descriptor: MANGANESE (II) ION, SULFATE ION, Xaa-pro aminopeptidase
Authors:Anderson, S.M, Wawrzak, Z, Skarina, T, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-07-27
Release date:2009-08-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of a putative aminopeptidase P from Bacillus anthracis
To be Published

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數據於2024-07-24公開中

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