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PDB: 2547 件

8UHG
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BU of 8uhg by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Vos, S.M, Su, B.G.
登録日2023-10-09
公開日2024-03-20
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
4Q7V
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BU of 4q7v by Molmil
Crystal structure of 1-hydroxy-5-methylpyridine-2(1H)-thione bound to human carbonic anhydrase II
分子名称: 1-hydroxy-5-methylpyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Martin, D.P, Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q83
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Crystal structure of 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II
分子名称: 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ...
著者Martin, D.P, Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q8X
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BU of 4q8x by Molmil
Crystal structure of 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione bound to human carbonic anhydrase II
分子名称: 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Martin, D.P, Cohen, S.M.
登録日2014-04-28
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
8UIS
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BU of 8uis by Molmil
Structure of transcription complex Pol II-DSIF-NELF-TFIIS
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Su, B.G, Vos, S.M.
登録日2023-10-10
公開日2024-03-20
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
8UHA
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BU of 8uha by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - tilted
分子名称: DNA (28-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ...
著者Vos, S.M, Su, B.G.
登録日2023-10-08
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
3GQV
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BU of 3gqv by Molmil
Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP
分子名称: Enoyl reductase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Ames, B.D, Smith, P.T, Ma, S.M, Kaake, R, Wong, E.W, Wong, S.K, Xie, X, Li, J.W, Vederas, J.C, Tang, Y, Tsai, S.-C.
登録日2009-03-24
公開日2009-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献biosynthesis of Lovastatin: Crystal structure and biochemical studies of LOVC, A trans-acting polyketide enoyl reductase
To be Published
8UHD
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BU of 8uhd by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ...
著者Su, B.G, Vos, S.M.
登録日2023-10-08
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 2024
2BG7
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BU of 2bg7 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
分子名称: BETA-LACTAMASE II, GLYCEROL, SULFATE ION, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-17
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2F9C
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BU of 2f9c by Molmil
Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6
分子名称: CESIUM ION, Hypothetical protein YDCK
著者Benach, J, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, H, Cooper, B, Acton, X.T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2005-12-05
公開日2005-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of YDCK from Salmonella cholerae NESG target SCR6.
To be Published
3LS0
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BU of 3ls0 by Molmil
Crystal Structure of Cyanobacterial PsbQ from Synechocystis sp. PCC 6803
分子名称: Sll1638 protein
著者Jackson, S.A, Fagerlund, R.D, Wilbanks, S.M, Eaton-Rye, J.J.
登録日2010-02-12
公開日2010-03-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of PsbQ from Synechocystis sp. PCC 6803 at 1.8 A: Implications for Binding and Function in Cyanobacterial Photosystem II
Biochemistry, 49, 2010
2BGG
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BU of 2bgg by Molmil
The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex.
分子名称: 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ...
著者Parker, J.S, Roe, S.M, Barford, D.
登録日2004-12-22
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex
Nature, 434, 2005
3HRU
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BU of 3hru by Molmil
Crystal Structure of ScaR with bound Zn2+
分子名称: Metalloregulator ScaR, SULFATE ION, ZINC ION
著者Stoll, K.E, Draper, W.E, Kliegman, J.I, Golynskiy, M.V, Brew-Appiah, R.A.T, Brown, H.K, Breyer, W.A, Jakubovics, N.S, Jenkinson, H.F, Brennan, R.B, Cohen, S.M, Glasfeld, A.
登録日2009-06-09
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
4MLX
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BU of 4mlx by Molmil
Structure of a bidentate 3-hydroxy-4H-pyran-4-thione ligand bound to hCAII
分子名称: 5-hydroxy-2-methyl-4H-pyran-4-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Martin, D.P, Cohen, S.M.
登録日2013-09-06
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献'Unconventional' coordination chemistry by metal chelating fragments in a metalloprotein active site.
J.Am.Chem.Soc., 136, 2014
2HDK
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BU of 2hdk by Molmil
Crystal Structure of Cys315Ala-Cys318Ala Mutant of Human Mitochondrial Branched Chain Aminotransferase
分子名称: 2-OXO-4-METHYLPENTANOIC ACID, ACETIC ACID, Branched-chain-amino-acid aminotransferase, ...
著者Yennawar, N.H, Hutson, S.M.
登録日2006-06-20
公開日2006-10-24
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS.
J.Biol.Chem., 281, 2006
4Q99
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BU of 4q99 by Molmil
Crystal structure of 2-mercapto-4-methylphenol bound to human carbonic anhydrase II
分子名称: 4-methyl-2-sulfanylphenol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Martin, D.P, Cohen, S.M.
登録日2014-04-29
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
2GWL
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BU of 2gwl by Molmil
Crystal structure of the Salmonella SpvB ATR Domain in complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 65 kDa virulence protein
著者Stebbins, C.E, Margarit, S.M.
登録日2006-05-04
公開日2006-08-29
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
1SKT
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BU of 1skt by Molmil
SOLUTION STRUCTURE OF APO N-DOMAIN OF TROPONIN C, NMR, 40 STRUCTURES
分子名称: TROPONIN-C
著者Tsuda, S, Miura, A, Gagne, S.M, Spyracopoulos, L, Sykes, B.D.
登録日1998-04-06
公開日1998-12-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Low-temperature-induced structural changes in the Apo regulatory domain of skeletal muscle troponin C.
Biochemistry, 38, 1999
2BG2
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BU of 2bg2 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in the buffer. 1mM DTT and 1mM TCEP- HCl were used as reducing agents. Cys221 is reduced.
分子名称: BETA-LACTAMASE II, CHLORIDE ION, GLYCEROL, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-16
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism.
Biochemistry, 44, 2005
2FFG
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BU of 2ffg by Molmil
Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360.
分子名称: ykuJ
著者Kuzin, A.P, Abashidze, M, Forouhar, F, Vorobiev, S.M, Ho, C.K, Janjua, H, Cunningham, K, Conover, K, Ma, L.C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2005-12-19
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360.
To be Published
2BFZ
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BU of 2bfz by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
分子名称: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-16
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
4Q6A
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BU of 4q6a by Molmil
Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH
分子名称: ACETATE ION, Dihydrofolate reductase, GLYCEROL, ...
著者Reeve, S.M, Anderson, A.C.
登録日2014-04-21
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Protein design algorithms predict viable resistance to an experimental antifolate.
Proc.Natl.Acad.Sci.USA, 112, 2015
2EW0
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BU of 2ew0 by Molmil
X-ray Crystal Structure of Protein Q6FF54 from Acinetobacter sp. ADP1. Northeast Structural Genomics Consortium Target AsR1.
分子名称: SULFATE ION, hypothetical protein ACIAD0353
著者Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Forouhar, F, Acton, T, Xiao, R, Northeast Structural Genomics Consortium (NESG)
登録日2005-11-01
公開日2005-12-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Novel x-ray structure of hypothetical protein Q6FF54 at the resolution 1.4 A. Northeast Structural Genomics target AsR1.
TO BE PUBLISHED
3MAN
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BU of 3man by Molmil
MANNOHEXAOSE COMPLEX OF THERMOMONOSPORA FUSCA BETA-MANNANASE
分子名称: PROTEIN (BETA-MANNANASE), beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose
著者Hilge, M, Gloor, S.M, Piontek, K.
登録日1998-08-12
公開日1999-08-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution native and complex structures of thermostable beta-mannanase from Thermomonospora fusca - substrate specificity in glycosyl hydrolase family 5.
Structure, 6, 1998
3IG4
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BU of 3ig4 by Molmil
Structure of a putative aminopeptidase P from Bacillus anthracis
分子名称: MANGANESE (II) ION, SULFATE ION, Xaa-pro aminopeptidase
著者Anderson, S.M, Wawrzak, Z, Skarina, T, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-07-27
公開日2009-08-04
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure of a putative aminopeptidase P from Bacillus anthracis
To be Published

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件を2024-07-24に公開中

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