5YN6
 
 | | Crystal structure of MERS-CoV nsp10/nsp16 complex bound to SAM | | 分子名称: | S-ADENOSYLMETHIONINE, ZINC ION, nsp10 protein, ... | | 著者 | Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P. | | 登録日 | 2017-10-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.947 Å) | | 主引用文献 | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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5YNN
 | | Crystal structure of MERS-CoV nsp16/nsp10complex bound to sinefungin and m7GpppG | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, SINEFUNGIN, ZINC ION, ... | | 著者 | Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P. | | 登録日 | 2017-10-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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1U68
 | | DHNA 7,8 DIHYDRONEOPTERIN COMPLEX | | 分子名称: | 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, Dihydroneopterin aldolase | | 著者 | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | | 登録日 | 2004-07-29 | | 公開日 | 2004-10-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.
J.MED.CHEM., 47, 2004
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6LNT
 | | Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab | | 分子名称: | Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ... | | 著者 | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | | 登録日 | 2020-01-02 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
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6TZT
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1KJI
 | | Crystal structure of glycinamide ribonucleotide transformylase in complex with Mg-AMPPCP | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | 著者 | Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. | | 登録日 | 2001-12-04 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site.
J.Biol.Chem., 277, 2002
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6U7I
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6CQY
 | | Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with EMPA and HI-6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ... | | 著者 | Bester, S.M, Guelta, M.A, Pegan, S.D, Height, J.J. | | 登録日 | 2018-03-16 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.449 Å) | | 主引用文献 | Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6.
Chem. Res. Toxicol., 31, 2018
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1TXO
 | | Crystal structure of the Mycobacterium tuberculosis serine/threonine phosphatase PstP/Ppp at 1.95 A. | | 分子名称: | MANGANESE (II) ION, Putative Bacterial Enzyme | | 著者 | Pullen, K.E, Ng, H.L, Sung, P.Y, Good, M.C, Smith, S.M, Alber, T, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2004-07-05 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | An Alternate Conformation and a Third Metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr Protein Phosphatase.
Structure, 12, 2004
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1U21
 | | transthyretin with tethered inhibitor on one monomer. | | 分子名称: | 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID, Transthyretin | | 著者 | Wiseman, R.L, Johnson, S.M, Kelker, M.S, Foss, T, Wilson, I.A, Kelly, J.W. | | 登録日 | 2004-07-16 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Kinetic stabilization of an oligomeric protein by a single ligand binding event
J.Am.Chem.Soc., 127, 2005
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3H2Y
 | | Crystal structure of YqeH GTPase from Bacillus anthracis with dGDP bound | | 分子名称: | 2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, GTPase family protein | | 著者 | Brunzelle, J.S, Anderson, S.M, Xu, X, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-04-15 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of YqeH GTPase from Bacillus anthracis with dGDP Bound
To be Published
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3GQQ
 | | Crystal structure of the human retinal protein 4 (unc-119 homolog A). Northeast Structural Genomics Consortium target HR3066a | | 分子名称: | Protein unc-119 homolog A, UNKNOWN LIGAND | | 著者 | Vorobiev, S.M, Chen, Y, Seetharaman, J, Shastry, R, Foote, E.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-03-24 | | 公開日 | 2009-04-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | | 主引用文献 | Crystal structure of the human retinal protein 4 (unc-119 homolog A).
To be Published
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8ELD
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8EM6
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6CF0
 | | Sperm Whale Myoglobin H64V Mutant with Nitrite | | 分子名称: | GLYCEROL, Myoglobin, NITRITE ION, ... | | 著者 | Powell, S.M, Wang, B, Thomas, L.M, Richter-Addo, G.B. | | 登録日 | 2018-02-13 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and Quantum Mechanics and Molecular Mechanics Theoretical Investigations of Preferred Fe -NO Ligand Orientations in Myoglobin Distal Pockets.
Biochemistry, 57, 2018
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6M7H
 | | Structure of calmodulin with KN93 | | 分子名称: | CALCIUM ION, Calmodulin-1, N-[2-[[[3-(4'-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4'-methoxybenzenesulfonamide | | 著者 | Damo, S.M, Pattanayek, R, Johnson, C.N. | | 登録日 | 2018-08-20 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function.
Cell Calcium, 82, 2019
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8ES4
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5YNI
 | | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYLMETHIONINE, ZINC ION, ... | | 著者 | Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P. | | 登録日 | 2017-10-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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5YNQ
 | | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppG | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | | 著者 | Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P. | | 登録日 | 2017-10-25 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.958 Å) | | 主引用文献 | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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6UQC
 | | Mouse IgG2a Bispecific Fc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, F, Tsai, J.C, Davis, J.H, West, S.M, Strop, P. | | 登録日 | 2019-10-18 | | 公開日 | 2020-01-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models.
Mabs, 12, 2019
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5YN5
 | | Crystal structure of MERS-CoV nsp10/nsp16 complex | | 分子名称: | ZINC ION, nsp10 protein, nsp16 protein | | 著者 | Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P. | | 登録日 | 2017-10-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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5YNF
 | | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppA | | 分子名称: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ZINC ION, nsp10 protein, ... | | 著者 | Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y. | | 登録日 | 2017-10-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | | 主引用文献 | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
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3FVW
 | | Crystal structure of the Q8DWD8_STRMU protein from Streptococcus mutans. Northeast Structural Genomics Consortium target SmR99. | | 分子名称: | Putative NAD(P)H-dependent FMN reductase | | 著者 | Vorobiev, S.M, Abashidze, M, Belote, R.L, Foote, E.L, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-01-16 | | 公開日 | 2009-02-10 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the Q8DWD8_STRMU protein from Streptococcus mutans.
To be Published
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3LS1
 | | Crystal Structure of Cyanobacterial PsbQ from Synechocystis sp. PCC 6803 complexed with Zn2+ | | 分子名称: | Sll1638 protein, ZINC ION | | 著者 | Jackson, S.A, Fagerlund, R.D, Wilbanks, S.M, Eaton-Rye, J.J. | | 登録日 | 2010-02-12 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of PsbQ from Synechocystis sp. PCC 6803 at 1.8 A: Implications for Binding and Function in Cyanobacterial Photosystem II
Biochemistry, 49, 2010
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4O96
 | | 2.60 Angstrom resolution crystal structure of a protein kinase domain of type III effector NleH2 (ECs1814) from Escherichia coli O157:H7 str. Sakai | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, type III effector protein kinase | | 著者 | Anderson, S.M, Halavaty, A.S, Wawrzak, Z, Kudritska, M, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-01-01 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Type III Effector NleH2 from Escherichia coli O157:H7 str. Sakai Features an Atypical Protein Kinase Domain.
Biochemistry, 53, 2014
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