1ZKY
 
 | | Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-3M and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide | | 分子名称: | 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 | | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Hahm, J.B, Nettles, K.W, Greene, G.L. | | 登録日 | 2005-05-04 | | 公開日 | 2006-05-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
J.Biol.Chem., 281, 2006
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2I1Y
 | | Crystal structure of the phosphatase domain of human PTP IA-2 | | 分子名称: | GLYCEROL, Receptor-type tyrosine-protein phosphatase | | 著者 | Faber-Barata, J, Patskovsky, Y, Alvarado, J, Smith, D, Koss, J, Wasserman, S.R, Ozyurt, S, Atwell, S, Powell, A, Kearins, M.C, Maletic, M, Rooney, I, Bain, K.T, Freeman, M, Russell, J.C, Thompson, D.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-08-15 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structural genomics of protein phosphatases
J.STRUCT.FUNCT.GENOM., 8, 2007
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2IA1
 | | Crystal structure of protein BH3703 from Bacillus halodurans, Pfam DUF600 | | 分子名称: | BH3703 protein, GLYCEROL, SULFATE ION | | 著者 | Ramagopal, U.A, Russell, M, Toro, R, Freeman, J.C, Reyes, C, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-09-06 | | 公開日 | 2006-10-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structure of hypothetical protein BH3703 from Bacillus halodurans
To be Published
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2HY3
 | | Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate | | 分子名称: | Receptor-type tyrosine-protein phosphatase gamma, VANADATE ION | | 著者 | Jin, X, Min, T, Bera, A, Mu, H, Sauder, J.M, Freeman, J.C, Reyes, C, Smith, D, Wasserman, S.R, Burley, S.K, Shapiro, L, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-08-04 | | 公開日 | 2006-09-05 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
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2I44
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2HXP
 | | Crystal Structure of the human phosphatase (DUSP9) | | 分子名称: | Dual specificity protein phosphatase 9, PHOSPHATE ION | | 著者 | Madegowda, M, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-08-03 | | 公開日 | 2006-08-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
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2HZT
 | | Crystal Structure of a putative HTH-type transcriptional regulator ytcD | | 分子名称: | Putative HTH-type transcriptional regulator ytcD | | 著者 | Madegowda, M, Eswaramoorthy, S, Desigan, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-08-09 | | 公開日 | 2006-08-29 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of a putative HTH-type transcription regulator ytcD
To be Published
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2K3V
 | | Solution Structure of a Tetrahaem Cytochrome from Shewanella Frigidimarina | | 分子名称: | HEME C, Tetraheme cytochrome c-type | | 著者 | Paixao, V.B, Turner, D.L, Salgueiro, C.A, Brennan, L, Reid, G.A, Chapman, S.K. | | 登録日 | 2008-05-19 | | 公開日 | 2009-03-31 | | 最終更新日 | 2019-10-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of a tetraheme cytochrome from Shewanella frigidimarina reveals a novel family structural motif
Biochemistry, 47, 2008
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1ZSH
 | | Crystal structure of bovine arrestin-2 in complex with inositol hexakisphosphate (IP6) | | 分子名称: | Beta-arrestin 1, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION | | 著者 | Milano, S.K, Kim, Y.M, Stefano, F.P, Benovic, J.L, Brenner, C. | | 登録日 | 2005-05-24 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding
J.Biol.Chem., 281, 2006
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2GU1
 | | Crystal structure of a zinc containing peptidase from vibrio cholerae | | 分子名称: | SODIUM ION, ZINC ION, Zinc peptidase | | 著者 | Sugadev, R, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-04-28 | | 公開日 | 2006-07-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a putative lysostaphin peptidase from Vibrio cholerae.
Proteins, 72, 2008
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2GVC
 | | Crystal structure of flavin-containing monooxygenase (FMO)from S.pombe and substrate (methimazole) complex | | 分子名称: | 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Eswaramoorthy, S, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-05-02 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Mechanism of action of a flavin-containing monooxygenase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZY4
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form. | | 分子名称: | GLYCEROL, Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZZW
 | | Crystal Structure of catalytic domain of Human MAP Kinase Phosphatase 5 | | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein phosphatase 10, SULFATE ION | | 著者 | Jeong, D.G, Yoon, T.S, Kim, J.H, Shim, M.Y, Jeong, S.K, Son, J.H, Ryu, S.E, Kim, S.J. | | 登録日 | 2005-06-14 | | 公開日 | 2006-07-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase.
J.Mol.Biol., 360, 2006
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1ZYC
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form. | | 分子名称: | Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZXM
 | | Human Topo IIa ATPase/AMP-PNP | | 分子名称: | DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, ... | | 著者 | Wei, H, Ruthenburg, A.J, Bechis, S.K, Verdine, G.L. | | 登録日 | 2005-06-08 | | 公開日 | 2005-08-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase.
J.Biol.Chem., 280, 2005
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1ZY5
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with AMPPNP. | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase GCN2 | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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1ZXE
 | | Crystal Structure of eIF2alpha Protein Kinase GCN2: D835N Inactivating Mutant in Apo Form | | 分子名称: | GLYCEROL, Serine/threonine-protein kinase | | 著者 | Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K. | | 登録日 | 2005-06-07 | | 公開日 | 2005-06-21 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
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2ADU
 | | Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor | | 分子名称: | 4-(3-METHYLPHENYL)-1H-1,2,3-TRIAZOLE, COBALT (II) ION, Methionine aminopeptidase 2 | | 著者 | Kallander, L.S, Lu, Q, Chen, W, Tomaszek, T, Yang, G, Tew, D, Meek, T.D, Hofmann, G.A, Schulz-Pritchard, C.K, Smith, W.W, Janson, C.A, Ryan, M.D, Zhang, G.F, Johanson, K.O, Kirkpatrick, R.B, Ho, T.F, Fisher, P.W, Mattern, M.R, Johnson, R.K, Hansbury, M.J, Winkler, J.D, Ward, K.W, Veber, D.F, Thompson, S.K. | | 登録日 | 2005-07-20 | | 公開日 | 2005-09-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | 4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo
J.Med.Chem., 48, 2005
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2GOK
 | | Crystal structure of the imidazolonepropionase from Agrobacterium tumefaciens at 1.87 A resolution | | 分子名称: | CHLORIDE ION, FE (III) ION, GLYCEROL, ... | | 著者 | Tyagi, R, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-04-13 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | X-ray structure of imidazolonepropionase from Agrobacterium tumefaciens at 1.87 A resolution.
Proteins, 69, 2007
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2A65
 | | Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters | | 分子名称: | CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ... | | 著者 | Yamashita, A, Singh, S.K, Kawate, T, Jin, Y, Gouaux, E. | | 登録日 | 2005-07-01 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters.
Nature, 437, 2005
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2KKI
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2PMQ
 | | Crystal structure of a mandelate racemase/muconate lactonizing enzyme from Roseovarius sp. HTCC2601 | | 分子名称: | MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme | | 著者 | Bonanno, J.B, Rutter, M, Bain, K.T, Lau, C, Sridhar, V, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-04-23 | | 公開日 | 2007-05-08 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Discovery of new enzymes and metabolic pathways by using structure and genome context.
Nature, 502, 2013
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2Q08
 | | Crystal structure of the protein BH0493 from Bacillus halodurans C-125 complexed with ZN | | 分子名称: | BH0493 protein, ZINC ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Patskovsky, Y, Sauder, J.M, Burley, S.K, Raushel, F, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-05-21 | | 公開日 | 2007-06-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of Glucoronate Isomerase from Bacillus halodurans.
To be Published
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2POF
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3KEP
 | | Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae | | 分子名称: | 1,2-ETHANEDIOL, Nucleoporin NUP145 | | 著者 | Sampathkumar, P, Ozyurt, S.A, Do, J, Bain, K, Dickey, M, Gheyi, T, Sali, A, Kim, S.J, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Rout, M, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-10-26 | | 公開日 | 2009-12-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.
Proteins, 78, 2010
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