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PDB: 10 results

1JSU
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BU of 1jsu by Molmil
P27(KIP1)/CYCLIN A/CDK2 COMPLEX
Descriptor: CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ...
Authors:Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1996-07-03
Release date:1997-07-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Nature, 382, 1996
1JST
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BU of 1jst by Molmil
PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE-2, ...
Authors:Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1996-07-03
Release date:1997-01-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of cyclin-dependent kinase activation by phosphorylation.
Nat.Struct.Biol., 3, 1996
1BI7
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BU of 1bi7 by Molmil
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX
Descriptor: CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR
Authors:Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BI8
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BU of 1bi8 by Molmil
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX
Descriptor: CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR
Authors:Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BYQ
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BU of 1byq by Molmil
HSP90 N-TERMINAL DOMAIN BOUND TO ADP-MG
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (HEAT SHOCK PROTEIN 90)
Authors:Russo, A.A, Pavletich, N.P.
Deposit date:1998-10-19
Release date:1998-10-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis.
J.Cell Biol., 143, 1998
1FIN
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BU of 1fin by Molmil
CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE 2
Authors:Jeffrey, P.D, Russo, A.A, Pavletich, N.P.
Deposit date:1996-07-14
Release date:1997-01-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Nature, 376, 1995
1GUX
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BU of 1gux by Molmil
RB POCKET BOUND TO E7 LXCXE MOTIF
Descriptor: ONCOPROTEIN, RETINOBLASTOMA PROTEIN
Authors:Lee, J.O, Russo, A.A, Pavletich, N.P.
Deposit date:1997-11-15
Release date:1998-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7.
Nature, 391, 1998
1YES
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BU of 1yes by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "OPEN" CONFORMATION
Descriptor: HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1YER
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BU of 1yer by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION
Descriptor: HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1YET
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BU of 1yet by Molmil
GELDANAMYCIN BOUND TO THE HSP90 GELDANAMYCIN-BINDING DOMAIN
Descriptor: GELDANAMYCIN, HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997

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