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PDB: 10 件
1JSU
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BU of 1jsu by Molmil
P27(KIP1)/CYCLIN A/CDK2 COMPLEX
分子名称: CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ...
著者Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
登録日1996-07-03
公開日1997-07-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Nature, 382, 1996
1JST
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PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE-2, ...
著者Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
登録日1996-07-03
公開日1997-01-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of cyclin-dependent kinase activation by phosphorylation.
Nat.Struct.Biol., 3, 1996
1BI7
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BU of 1bi7 by Molmil
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX
分子名称: CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR
著者Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
登録日1998-06-22
公開日1999-01-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BI8
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MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX
分子名称: CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR
著者Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
登録日1998-06-22
公開日1999-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BYQ
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BU of 1byq by Molmil
HSP90 N-TERMINAL DOMAIN BOUND TO ADP-MG
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (HEAT SHOCK PROTEIN 90)
著者Russo, A.A, Pavletich, N.P.
登録日1998-10-19
公開日1998-10-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis.
J.Cell Biol., 143, 1998
1FIN
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BU of 1fin by Molmil
CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE 2
著者Jeffrey, P.D, Russo, A.A, Pavletich, N.P.
登録日1996-07-14
公開日1997-01-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Nature, 376, 1995
1GUX
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BU of 1gux by Molmil
RB POCKET BOUND TO E7 LXCXE MOTIF
分子名称: ONCOPROTEIN, RETINOBLASTOMA PROTEIN
著者Lee, J.O, Russo, A.A, Pavletich, N.P.
登録日1997-11-15
公開日1998-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7.
Nature, 391, 1998
1YES
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BU of 1yes by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "OPEN" CONFORMATION
分子名称: HEAT SHOCK PROTEIN 90
著者Stebbins, C.E, Russo, A.A, Pavletich, N.P.
登録日1997-03-25
公開日1998-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1YER
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BU of 1yer by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION
分子名称: HEAT SHOCK PROTEIN 90
著者Stebbins, C.E, Russo, A.A, Pavletich, N.P.
登録日1997-03-25
公開日1998-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1YET
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GELDANAMYCIN BOUND TO THE HSP90 GELDANAMYCIN-BINDING DOMAIN
分子名称: GELDANAMYCIN, HEAT SHOCK PROTEIN 90
著者Stebbins, C.E, Russo, A.A, Pavletich, N.P.
登録日1997-03-25
公開日1998-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997

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