1AJ8
 
 | | CITRATE SYNTHASE FROM PYROCOCCUS FURIOSUS | | Descriptor: | CITRATE SYNTHASE, CITRIC ACID, COENZYME A | | Authors: | Russell, R.J.M, Ferguson, J.M.C, Hough, D.W, Danson, M.J, Taylor, G.L. | | Deposit date: | 1997-05-16 | | Release date: | 1997-11-19 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The crystal structure of citrate synthase from the hyperthermophilic archaeon pyrococcus furiosus at 1.9 A resolution,.
Biochemistry, 36, 1997
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1A59
 | | COLD-ACTIVE CITRATE SYNTHASE | | Descriptor: | CITRATE SYNTHASE, CITRIC ACID, COENZYME A | | Authors: | Russell, R.J.M, Gerike, U, Danson, M.J, Hough, D.W, Taylor, G.L. | | Deposit date: | 1998-02-20 | | Release date: | 1999-03-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium.
Structure, 6, 1998
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1O9M
 | | The Complex of a novel antibiotic with the Aminoacyl Site of the Bacterial Ribosome Revealed by X-Ray Crystallography. | | Descriptor: | 1-(AMINOETHYL)AMINO-4-AMINOBUTANE, 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose, 4-AMINO-2-HYDROXYBUTANOIC ACID, ... | | Authors: | Russell, R, Murray, J.B. | | Deposit date: | 2002-12-17 | | Release date: | 2003-03-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Complex of a Designer Antibiotic with a Model Aminoacyl Site of the 30S Ribosomal Subunit Revealed by X-Ray Crystallography
J.Am.Chem.Soc., 125, 2003
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1TI8
 | | H7 Haemagglutinin | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... | | Authors: | Russell, R.J, Gamblin, S.J, Haire, L.F, Stevens, D.J, Xaio, B, Ha, Y, Skehel, J.J. | | Deposit date: | 2004-06-02 | | Release date: | 2005-06-21 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.
Virology, 325, 2004
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3EYM
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | Descriptor: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | Authors: | Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2008-10-21 | | Release date: | 2009-01-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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3EYK
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | Descriptor: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | Authors: | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2008-10-21 | | Release date: | 2009-01-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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3O9K
 | | Influenza NA in complex with compound 6 | | Descriptor: | 5-acetamido-2,6-anhydro-3,5-dideoxy-3-[(2E)-3-(4-methylphenyl)prop-2-en-1-yl]-D-glycero-D-galacto-non-2-enonic acid, Neuraminidase | | Authors: | Russell, R.J, Kerry, P.S. | | Deposit date: | 2010-08-04 | | Release date: | 2010-12-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.4945 Å) | | Cite: | Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
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3O9J
 | | Influenza NA in complex with compound 5 | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 5-acetamido-2,6-anhydro-3,5-dideoxy-3-prop-2-en-1-yl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | | Authors: | Russell, R.J, Kerry, P.S. | | Deposit date: | 2010-08-04 | | Release date: | 2010-12-15 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.0002 Å) | | Cite: | Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
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3EYJ
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | Descriptor: | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | Authors: | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinahuer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2008-10-21 | | Release date: | 2009-01-13 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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2HU0
 | | N1 neuraminidase in complex with oseltamivir 1 | | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTY
 | | N1 neuraminidase | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HT8
 | | N8 neuraminidase in complex with oseltamivir | | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTV
 | | N4 neuraminidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTQ
 | | N8 neuraminidase in complex with zanamivir | | Descriptor: | Neuraminidase, ZANAMIVIR | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HT5
 | | N8 Neuraminidase | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-05 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTR
 | | N8 neuraminidase in complex with DANA | | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTU
 | | N8 neuraminidase in complex with peramivir | | Descriptor: | 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HT7
 | | N8 neuraminidase in open complex with oseltamivir | | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTW
 | | N4 neuraminidase in complex with DANA | | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HU4
 | | N1 neuraminidase in complex with oseltamivir 2 | | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | Authors: | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-05 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2F4V
 | | 30S ribosome + designer antibiotic | | Descriptor: | (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ... | | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | | Deposit date: | 2005-11-24 | | Release date: | 2006-07-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
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3CKZ
 | | N1 Neuraminidase H274Y + Zanamivir | | Descriptor: | CALCIUM ION, Neuraminidase, ZANAMIVIR | | Authors: | Colllins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | Deposit date: | 2008-03-18 | | Release date: | 2008-05-20 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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7U8K
 | | Magic Angle Spinning NMR Structure of Human Cofilin-2 Assembled on Actin Filaments | | Descriptor: | Actin, alpha skeletal muscle, Cofilin-2 | | Authors: | Kraus, J, Russell, R, Kudryashova, E, Xu, C, Katyal, N, Kudryashov, D, Perilla, J.R, Polenova, T. | | Deposit date: | 2022-03-08 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-23 | | Method: | SOLID-STATE NMR | | Cite: | Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode.
Nat Commun, 13, 2022
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4D8S
 | | Influenza NA in complex with antiviral compound | | Descriptor: | CALCIUM ION, Neuraminidase, pentan-3-yl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid | | Authors: | Kerry, P.S, Russell, R.J.M.R. | | Deposit date: | 2012-01-11 | | Release date: | 2013-02-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.398 Å) | | Cite: | Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.
J.Med.Chem., 55, 2012
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8CX6
 | | TPX2 Minimal Active Domain on Microtubules | | Descriptor: | Targeting protein for Xklp2-A | | Authors: | Guo, C, Alfaro-Aco, R, Russell, R, Zhang, C, Petry, S, Polenova, T. | | Deposit date: | 2022-05-19 | | Release date: | 2023-06-28 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Structural basis of protein condensation on microtubules underlying branching microtubule nucleation.
Nat Commun, 14, 2023
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