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PDB: 6 件
7ZQY
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BU of 7zqy by Molmil
Chaetomium thermophilum Rad50 Zn hook
分子名称: DH domain-containing protein, ZINC ION
著者Lammens, K, Rotheneder, M, Stakyte, K.
登録日2022-05-03
公開日2022-12-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
8BAH
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BU of 8bah by Molmil
Human Mre11-Nbs1 complex
分子名称: Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin
著者Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P.
登録日2022-10-11
公開日2023-01-11
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (4.13 Å)
主引用文献Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
7ZR1
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BU of 7zr1 by Molmil
Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure)
分子名称: DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ...
著者Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P.
登録日2022-05-03
公開日2023-01-11
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
7NI4
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BU of 7ni4 by Molmil
Human ATM kinase domain with bound M4076 inhibitor
分子名称: 8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoranyl-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-imidazo[4,5-c]quinolin-2-one, Serine-protein kinase ATM, ZINC ION
著者Stakyte, K, Rotheneder, M.
登録日2021-02-11
公開日2021-09-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis of human ATM kinase inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7NI5
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BU of 7ni5 by Molmil
Human ATM kinase with bound inhibitor KU-55933
分子名称: 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one, Serine-protein kinase ATM, ZINC ION
著者Bartho, J.D, Stakyte, K, Rotheneder, M, Lammens, K, Hopfner, K.P.
登録日2021-02-11
公開日2021-09-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Molecular basis of human ATM kinase inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7NI6
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BU of 7ni6 by Molmil
Human ATM kinase with bound ATPyS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM, ...
著者Stakyte, K, Rotheneder, M, Lammens, K, Bartho, J.D.
登録日2021-02-11
公開日2021-09-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular basis of human ATM kinase inhibition.
Nat.Struct.Mol.Biol., 28, 2021

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件を2024-10-30に公開中

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