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PDB: 655 results

6D64
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BU of 6d64 by Molmil
Crystal Structure of Human CD1b in Complex with POPC
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-ETHANEDIOL, Beta-2-microglobulin, ...
Authors:Shahine, A.E, Rossjohn, J.
Deposit date:2018-04-20
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10, 2019
6D2T
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BU of 6d2t by Molmil
HLA-B*57:01 presenting LALLTGVRW
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2018-04-13
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
6C3R
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BU of 6c3r by Molmil
Cricket paralysis virus RNAi suppressor protein CrPV-1A
Descriptor: Cricket paralysis virus 1A protein
Authors:Nayak, A, Kim, D.Y, Andino, R, Gross, J.
Deposit date:2018-01-10
Release date:2018-10-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
Cell Host Microbe, 24, 2018
6BXQ
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BU of 6bxq by Molmil
Crystal Structure of HLA-B*57:01 with an HIV peptide RKV
Descriptor: Beta-2-microglobulin, HIV peptide RKV, MHC class I antigen
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-12-18
Release date:2018-02-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.
Proteomics, 18, 2018
2AK4
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BU of 2ak4 by Molmil
Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide
Descriptor: Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ...
Authors:Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J.
Deposit date:2005-08-03
Release date:2005-10-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
2ARL
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The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding
Descriptor: ACETIC ACID, CHLORIDE ION, GFP-like non-fluorescent chromoprotein, ...
Authors:Wilmann, P.G, Battad, J, Beddoe, T, Olsen, S, Smith, S.C, Dove, S, Devenish, R.J, Rossjohn, J, Prescott, M.
Deposit date:2005-08-19
Release date:2006-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding
Photochem.Photobiol., 82, 2006
2AXF
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BU of 2axf by Molmil
The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
Descriptor: 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ...
Authors:Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2005-09-05
Release date:2005-11-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
J.Exp.Med., 202, 2005
2ESV
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BU of 2esv by Molmil
Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Hoare, H.L, Rossjohn, J.
Deposit date:2005-10-27
Release date:2006-03-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for a major histocompatibility complex class Ib-restricted T cell response
Nat.Immunol., 7, 2006
6AVG
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BU of 6avg by Molmil
Crystal structure of the KFJ37 TCR-NY-ESO-1-HLA-B*07:02 complex
Descriptor: ALA-PRO-ARG-GLY-PRO-HIS-GLY-GLY-ALA-ALA-SER-GLY-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gully, B.S, Gras, S, Rossjohn, J.
Deposit date:2017-09-02
Release date:2018-02-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018
1SNG
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BU of 1sng by Molmil
Structure of a Thermophilic Serpin in the Native State
Descriptor: COG4826: Serine protease inhibitor, SULFATE ION
Authors:Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C.
Deposit date:2004-03-10
Release date:2004-12-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.
J.Biol.Chem., 280, 2005
6ARQ
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BU of 6arq by Molmil
Crystal structure of CD96 (D1) bound to CD155/necl-5 (D1-3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, T-cell surface protein tactile, ...
Authors:Deuss, F.A, Watson, G.M, Rossjohn, J, Berry, R.
Deposit date:2017-08-23
Release date:2018-11-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Structure, 27, 2019
7M72
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BU of 7m72 by Molmil
MHC-like protein complex structure
Descriptor: (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxy-15-methylhexadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Thirunavukkarasu, P, Le Nours, J, Rossjohn, J.
Deposit date:2021-03-26
Release date:2021-11-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
3P4M
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BU of 3p4m by Molmil
Crystal Structure of H2-Kb in complex with the NP205-LCMV epitope YTVKYPNL, an 8-mer peptide from the LCMV
Descriptor: ACETYL GROUP, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Gras, S, Guillonneau, C, Rossjohn, J.
Deposit date:2010-10-06
Release date:2011-10-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of H2-Kb in complex with the NP205-LCMV epitope YTVKYPNL, an 8-mer peptide from the LCMV
To be Published
3SDA
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BU of 3sda by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-beta-galactosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Clarke, A.J, Rossjohn, J.
Deposit date:2011-06-08
Release date:2011-10-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
3SDC
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BU of 3sdc by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-globotrihexosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Clarke, A.J, Rossjohn, J.
Deposit date:2011-06-09
Release date:2011-10-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
3SJV
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BU of 3sjv by Molmil
Crystal structure of the RL42 TCR in complex with HLA-B8-FLR
Descriptor: Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J.
Deposit date:2011-06-22
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
J.Immunol., 188, 2012
6BIV
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BU of 6biv by Molmil
HLA-DRB1 in complex with citrullinated LL37 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-11-03
Release date:2018-01-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BIX
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BU of 6bix by Molmil
HLA-DRB1 in complex with citrullinated LL37 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II DR-beta (HLA-DR B), HLA class II histocompatibility antigen, ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-11-03
Release date:2018-01-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BIL
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BU of 6bil by Molmil
HLA-DRB1 in complex with citrullinated fibrinogen peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 74cit69-81, HLA class II histocompatibility antigen, ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-11-02
Release date:2018-01-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BIJ
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BU of 6bij by Molmil
HLA-DRB1 in complex with citrullinated fibrinogen peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Citrullinated Fibrinogen 72,74Cit69-81, HLA class II histocompatibility antigen, ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-11-02
Release date:2018-01-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BIY
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BU of 6biy by Molmil
HLA-DRB1 in complex with Histone 2B peptide
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II DR-beta (HLA-DR B), ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-11-03
Release date:2018-01-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.050049 Å)
Cite:The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BIR
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BU of 6bir by Molmil
HLA-DRB1 in complex with citrullinated Vimentin peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-11-02
Release date:2018-01-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
3P9L
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BU of 3p9l by Molmil
Crystal Structure of H2-Kb in complex with the chicken ovalbumin epitope OVA
Descriptor: Beta-2-microglobulin, CALCIUM ION, H-2 class I histocompatibility antigen, ...
Authors:Wesselingh, R, Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J.
Deposit date:2010-10-18
Release date:2011-10-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses
J.Immunol., 187, 2011
6V2O
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BU of 6v2o by Molmil
HLA-B*57:01 presenting the peptide ASLNLPAVSW
Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ...
Authors:Maclachlan, B, Rossjohn, J, Vivian, J.P.
Deposit date:2019-11-25
Release date:2020-05-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6V80
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Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
Authors:Shahine, A, Rossjohn, J.
Deposit date:2019-12-10
Release date:2020-09-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response.
Nat Cancer, 2020

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