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PDB: 633 results

7JSS
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BU of 7jss by Molmil
ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-15
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes.
Nat Commun, 11, 2020
8EG5
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BU of 8eg5 by Molmil
huCaspase-6 in complex with inhibitor 3a
Descriptor: (3R,5S)-1-(ethanesulfonyl)-5-phenyl-N-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxamide (bound form), 1,2-ETHANEDIOL, Caspase-6 subunit p11, ...
Authors:Zhao, Y, Fan, P, Liu, J, Wang, Y, Van Horn, K, Wang, D, Medina-Cleghorn, D, Lee, P, Bryant, C, Altobelli, C, Jaishankar, P, Ng, R.A, Ambrose, A.J, Tang, Y, Arkin, M.R, Renslo, A.R.
Deposit date:2022-09-11
Release date:2023-05-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6.
J.Am.Chem.Soc., 145, 2023
8DGA
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BU of 8dga by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DFV
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BU of 8dfv by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa
Descriptor: CALCIUM ION, Endoribonuclease Dcr-1, Loquacious, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-22
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DG7
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BU of 8dg7 by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
8DG5
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BU of 8dg5 by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
6TI9
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BU of 6ti9 by Molmil
Human transthyretin (TTR) complexed with (E)-3-(((3,5-dibromo-2-hydroxybenzylidene)amino)oxy)propanoic acid.
Descriptor: 3-[(~{E})-[3,5-bis(bromanyl)-2-oxidanyl-phenyl]methylideneamino]oxypropanoic acid, GLYCEROL, S-1,2-PROPANEDIOL, ...
Authors:Ciccone, L, Nencetti, S, Orlandini, E, Rossello, A, Legrand, P, Shepard, W.
Deposit date:2019-11-22
Release date:2020-10-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis.
Bioorg.Med.Chem., 28, 2020
7JSW
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BU of 7jsw by Molmil
ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes.
Nat Commun, 11, 2020
6TJN
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BU of 6tjn by Molmil
Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid
Descriptor: 3-[(~{E})-(4-hydroxyphenyl)methylideneamino]oxypropanoic acid, Transthyretin
Authors:Ciccone, L, Shepard, W, Nencetti, S, Orlandini, E, Rossello, A.
Deposit date:2019-11-26
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis.
Bioorg.Med.Chem., 28, 2020
8FMA
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BU of 8fma by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer
Descriptor: RNA-directed RNA polymerase
Authors:Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
Deposit date:2022-12-22
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FM9
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BU of 8fm9 by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer
Descriptor: RNA-directed RNA polymerase
Authors:Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
Deposit date:2022-12-22
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FMB
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BU of 8fmb by Molmil
Nodavirus RNA replication protein A polymerase domain, local refinement
Descriptor: RNA-directed RNA polymerase
Authors:Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
Deposit date:2022-12-22
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
7JT2
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BU of 7jt2 by Molmil
70S ribosome stalled on long mRNA with ArfB bound in the A site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020
7K53
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BU of 7k53 by Molmil
Pre-translocation +1-frameshifting(CCC-A) complex (Structure I-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K51
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BU of 7k51 by Molmil
Mid-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K50
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BU of 7k50 by Molmil
Pre-translocation non-frameshifting(CCA-A) complex (Structure I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K55
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BU of 7k55 by Molmil
Near post-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure III-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K54
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BU of 7k54 by Molmil
Mid-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure II-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K52
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BU of 7k52 by Molmil
Near post-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
6HRN
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BU of 6hrn by Molmil
C-Phycocyanin from heterocyst forming filamentous cyanobacterium Nostoc sp. WR13
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha Subunit of Cyanobacterial Phycocyanin protein, Beta Subunit of Cyanobacterial Phycocyanin protein, ...
Authors:Patel, H.M, Roszak, A.W, Madamwar, D, Cogdell, R.J.
Deposit date:2018-09-27
Release date:2019-06-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.513 Å)
Cite:Crystal structure of phycocyanin from heterocyst-forming filamentous cyanobacterium Nostoc sp. WR13.
Int.J.Biol.Macromol., 135, 2019
7JT3
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BU of 7jt3 by Molmil
Rotated 70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound in the A site (+9-IV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-17
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020
7JSZ
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BU of 7jsz by Molmil
ArfB Rescue of a 70S Ribosome stalled on truncated mRNA with a partial A-site codon (+2-IV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes.
Nat Commun, 11, 2020
7L6G
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BU of 7l6g by Molmil
MbnP from Methylosinus trichosporium
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, COPPER (II) ION, ...
Authors:Manesis, A.C, Rosenzweig, A.C.
Deposit date:2020-12-23
Release date:2021-05-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Copper binding by a unique family of metalloproteins is dependent on kynurenine formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7TRJ
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BU of 7trj by Molmil
The eukaryotic translation initiation factor 2B from Homo sapiens with a H160D mutation in the beta subunit
Descriptor: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
Authors:Wang, L, Schoof, M, Lawrence, R, Boone, M, Frost, A, Walter, P.
Deposit date:2022-01-29
Release date:2022-04-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation.
Elife, 11, 2022
7JT1
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BU of 7jt1 by Molmil
70S ribosome stalled on long mRNA with ArfB-1 and ArfB-2 bound (+9-III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020

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