7SSS

Structure of the NADH-bound human COQ7:COQ9 complex by single-particle electron cryo-microscopy

Summary for 7SSS

Entry DOI	10.2210/pdb7sss/pdb
EMDB information	25413
Descriptor	Ubiquinone biosynthesis protein COQ9, mitochondrial, 5-demethoxyubiquinone hydroxylase, mitochondrial, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ... (6 entities in total)
Functional Keywords	hydroxylase, complex, lipid, enzyme, nadh, coenzymeq, isoprene, opp, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	266375.46
Authors	Aydin, H.,Frost, A. (deposition date: 2021-11-11, release date: 2022-11-02, Last modification date: 2024-06-05)
Primary citation	Manicki, M.,Aydin, H.,Abriata, L.A.,Overmyer, K.A.,Guerra, R.M.,Coon, J.J.,Dal Peraro, M.,Frost, A.,Pagliarini, D.J. Structure and functionality of a multimeric human COQ7:COQ9 complex. Mol.Cell, 82:4307-4323.e10, 2022 Cited by PubMed: 36306796 DOI: 10.1016/j.molcel.2022.10.003 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.4 Å)

Structure validation