7SSS

Structure of the NADH-bound human COQ7:COQ9 complex by single-particle electron cryo-microscopy

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006744	biological_process	ubiquinone biosynthetic process
A	0008047	molecular_function	enzyme activator activity
A	0008289	molecular_function	lipid binding
A	0019840	molecular_function	isoprenoid binding
A	0042803	molecular_function	protein homodimerization activity
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006744	biological_process	ubiquinone biosynthetic process
B	0008047	molecular_function	enzyme activator activity
B	0008289	molecular_function	lipid binding
B	0019840	molecular_function	isoprenoid binding
B	0042803	molecular_function	protein homodimerization activity
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006744	biological_process	ubiquinone biosynthetic process
C	0008047	molecular_function	enzyme activator activity
C	0008289	molecular_function	lipid binding
C	0019840	molecular_function	isoprenoid binding
C	0042803	molecular_function	protein homodimerization activity
D	0005515	molecular_function	protein binding
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0006744	biological_process	ubiquinone biosynthetic process
D	0008047	molecular_function	enzyme activator activity
D	0008289	molecular_function	lipid binding
D	0019840	molecular_function	isoprenoid binding
D	0042803	molecular_function	protein homodimerization activity
E	0004497	molecular_function	monooxygenase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005694	cellular_component	chromosome
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006744	biological_process	ubiquinone biosynthetic process
E	0008340	biological_process	determination of adult lifespan
E	0016491	molecular_function	oxidoreductase activity
E	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
E	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
E	0046872	molecular_function	metal ion binding
E	0160224	molecular_function	3-demethoxyubiquinone 3-hydroxylase (NADH) activity
E	2000377	biological_process	regulation of reactive oxygen species metabolic process
F	0004497	molecular_function	monooxygenase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005694	cellular_component	chromosome
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0006744	biological_process	ubiquinone biosynthetic process
F	0008340	biological_process	determination of adult lifespan
F	0016491	molecular_function	oxidoreductase activity
F	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
F	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
F	0046872	molecular_function	metal ion binding
F	0160224	molecular_function	3-demethoxyubiquinone 3-hydroxylase (NADH) activity
F	2000377	biological_process	regulation of reactive oxygen species metabolic process
G	0004497	molecular_function	monooxygenase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005694	cellular_component	chromosome
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006744	biological_process	ubiquinone biosynthetic process
G	0008340	biological_process	determination of adult lifespan
G	0016491	molecular_function	oxidoreductase activity
G	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
G	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
G	0046872	molecular_function	metal ion binding
G	0160224	molecular_function	3-demethoxyubiquinone 3-hydroxylase (NADH) activity
G	2000377	biological_process	regulation of reactive oxygen species metabolic process
H	0004497	molecular_function	monooxygenase activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005694	cellular_component	chromosome
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006744	biological_process	ubiquinone biosynthetic process
H	0008340	biological_process	determination of adult lifespan
H	0016491	molecular_function	oxidoreductase activity
H	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
H	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
H	0046872	molecular_function	metal ion binding
H	0160224	molecular_function	3-demethoxyubiquinone 3-hydroxylase (NADH) activity
H	2000377	biological_process	regulation of reactive oxygen species metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25339443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30661980","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AWL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8K1Z0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	324
Details	Repeat: {"description":"1"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	348
Details	Repeat: {"description":"2"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	676
Details	Region: {"description":"2 X approximate tandem repeats"}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36306796","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SSS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03194","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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