7SSS

Structure of the NADH-bound human COQ7:COQ9 complex by single-particle electron cryo-microscopy

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A	0006744	biological_process	ubiquinone biosynthetic process
A	0008289	molecular_function	lipid binding
A	0042803	molecular_function	protein homodimerization activity
A	0110142	cellular_component	ubiquinone biosynthesis complex
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B	0006744	biological_process	ubiquinone biosynthetic process
B	0008289	molecular_function	lipid binding
B	0042803	molecular_function	protein homodimerization activity
B	0110142	cellular_component	ubiquinone biosynthesis complex
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
C	0006744	biological_process	ubiquinone biosynthetic process
C	0008289	molecular_function	lipid binding
C	0042803	molecular_function	protein homodimerization activity
C	0110142	cellular_component	ubiquinone biosynthesis complex
D	0005515	molecular_function	protein binding
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
D	0006744	biological_process	ubiquinone biosynthetic process
D	0008289	molecular_function	lipid binding
D	0042803	molecular_function	protein homodimerization activity
D	0110142	cellular_component	ubiquinone biosynthesis complex
E	0004497	molecular_function	monooxygenase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005694	cellular_component	chromosome
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006744	biological_process	ubiquinone biosynthetic process
E	0008340	biological_process	determination of adult lifespan
E	0008682	molecular_function	3-demethoxyubiquinol 3-hydroxylase activity
E	0010468	biological_process	regulation of gene expression
E	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
E	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
E	0046872	molecular_function	metal ion binding
E	0110142	cellular_component	ubiquinone biosynthesis complex
E	2000377	biological_process	regulation of reactive oxygen species metabolic process
F	0004497	molecular_function	monooxygenase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005694	cellular_component	chromosome
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0006744	biological_process	ubiquinone biosynthetic process
F	0008340	biological_process	determination of adult lifespan
F	0008682	molecular_function	3-demethoxyubiquinol 3-hydroxylase activity
F	0010468	biological_process	regulation of gene expression
F	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
F	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
F	0046872	molecular_function	metal ion binding
F	0110142	cellular_component	ubiquinone biosynthesis complex
F	2000377	biological_process	regulation of reactive oxygen species metabolic process
G	0004497	molecular_function	monooxygenase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005694	cellular_component	chromosome
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006744	biological_process	ubiquinone biosynthetic process
G	0008340	biological_process	determination of adult lifespan
G	0008682	molecular_function	3-demethoxyubiquinol 3-hydroxylase activity
G	0010468	biological_process	regulation of gene expression
G	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
G	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
G	0046872	molecular_function	metal ion binding
G	0110142	cellular_component	ubiquinone biosynthesis complex
G	2000377	biological_process	regulation of reactive oxygen species metabolic process
H	0004497	molecular_function	monooxygenase activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005694	cellular_component	chromosome
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006744	biological_process	ubiquinone biosynthetic process
H	0008340	biological_process	determination of adult lifespan
H	0008682	molecular_function	3-demethoxyubiquinol 3-hydroxylase activity
H	0010468	biological_process	regulation of gene expression
H	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
H	0031314	cellular_component	extrinsic component of mitochondrial inner membrane
H	0046872	molecular_function	metal ion binding
H	0110142	cellular_component	ubiquinone biosynthesis complex
H	2000377	biological_process	regulation of reactive oxygen species metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:25339443, ECO:0007744|PDB:4RHP

Chain	Residue	Details
A	TYR241
F	GLU142
F	GLU178
F	HIS181
G	GLU60
G	GLU90
G	HIS93
G	GLU142
G	GLU178
G	HIS181
H	GLU60
B	TYR241
H	GLU90
H	HIS93
H	GLU142
H	GLU178
H	HIS181
C	TYR241
D	TYR241
E	GLU178
E	HIS181
F	GLU60
F	GLU90
F	HIS93

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8K1Z0

Chain	Residue	Details
A	LYS175
B	LYS175
C	LYS175
D	LYS175

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